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Essential Measures are only those items that are critical to the collection of the Measure or are necessary for the interpretation of results. Essential Measures are integral to the Measure. Without such information the data collected would be incomplete and/or misleading.
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Browse » Domains » Diabetes » Fasting Serum Insulin

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Measure: Fasting Serum Insulin   #141300

Definition:

A bioassay to measure serum concentration of insulin, a hormone produced by pancreatic beta cells that regulates the body’s ability to metabolize glucose.

Purpose:

Concentrations of serum insulin may help distinguish between type 1 and type 2 diabetes. Type 1, or insulin-dependent, diabetes is characterized by autoimmune destruction of the pancreas and eventually leads to absolute insulin deficiency and very low or no circulating insulin. Type 2, or non-insulin-dependent, diabetes is characterized by insulin resistance and subjects initially have much higher circulating insulin concentrations. This may be followed by decreasing insulin levels due to pancreatic beta cell exhaustion (ADA, 2014). Further, fasting serum insulin alone or combined with fasting plasma glucose can be used as a surrogate estimate of insulin resistance and beta-cell function.

Protocols:

Keywords:

Diabetes, proinsulin, C-peptide, pancreas, hyperglycemia, homeostatic model assessment, HOMA, insulin resistance, NHANES

Measure Release Date: October 1, 2015

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