Inhibitors |
Factor IX Activity in Plasma |
Factor VIII Activity in Plasma |
Quantitative Measure of Factor IX Inhibitor Activity |
Quantitative Measure of Factor VIII Inhibitor Activity |
Quantitative Measure of Factor VIII Inhibitor Activity in the Presence of Emicizumab |
Bleeding |
Counts of Acute Bleeds in Hemophilia |
Outcome measures to evaluate effectiveness of therapy |
Response to Factor IX Infusion - Individual Pharmacokinetic Study |
Response to Factor IX Infusion - Population-based Pharmacokinetic Study |
Response to Factor VIII Infusion - Individual Pharmacokinetic Study |
Response to Factor VIII Infusion - Population-based Pharmacokinetic Study |
Response to Factor VIII Infusion in the Presence of Emicizumab - Individual Pharmacokinetic Study |
Response to Factor VIII Infusion in the Presence of Emicizumab - Population-based Pharmacokinetic Study |
Patient reported outcomes |
School and Work Attendance |
Disease-specific Health-related Quality of Life in Hemophilia |
Physical activity and function |
Hemophilia-specific Functional Activity |
Joint health Score |
Adherence to treatment |
Patient Recall of Clotting Factor Administration |
Utilization of health care |
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