Protocol - Axial Spondyloarthritis (AxSpA)
Description
The six-item, self-administered, Likert-style index includes patient-reported levels of back pain, fatigue, peripheral joint pain and swelling, localized tenderness, and the duration and severity of morning stiffness in the last week.
Specific Instructions
None
Availability
Protocol
Please tick the box which represents your answer.
All questions refer to last week.
- How would you describe the overall level of fatigue/tiredness you have experienced?
None | 0 | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | Very severe |
- How would you describe the overall level of AS neck, back or hip pain you have had?
None | 0 | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | Very severe |
- How would you describe the overall level of pain/swelling in joints other than neck, back or hips you have had?
None | 0 | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | Very severe |
- How would you describe the overall level of discomfort you have had from any areas tender to touch or pressure?
None | 0 | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | Very severe |
- How would you describe the overall level of morning stiffness you have had from the time you wake up?
None | 0 | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | Very severe |
- How long does your morning stiffness last from the time you wake up?
0 | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 |
0 hrs | 1 hr | 2 or more hrs |
Recommendations to score:
The scores for questions 5 and 6 (severity and duration of morning stiffness) are averaged; the result is then averaged with the remaining 4 question scores to give a final score out of 10.
Score Interpretation
Ranges from 0 (no disease activity) to 10 (maximal disease activity).
Cut-off points
Define: A cut off of ≥ 4 is used to define active disease. Reference percentile charts have been published. A 50% or 2 units (0-10) improvement in BASDAI with an intervention has been defined as a response to that intervention.
Personnel and Training Required
None
Equipment Needs
None
Requirements
| Requirement Category | Required |
|---|---|
| Major equipment | No |
| Specialized training | No |
| Specialized requirements for biospecimen collection | No |
| Average time of greater than 15 minutes in an unaffected individual | No |
Mode of Administration
Self-administered questionnaire
Lifestage
Adolescent, Adult, Senior
Participants
Cross-section of adolescent and/or adult patients, including inpatients receiving 3 weeks of intensive physiotherapy treatment, and hospital outpatients.
Selection Rationale
The instrument was first published in 1994 and is validated and widely used in clinical practice and research. It is user friendly, reliable, sensitive to change, and reflects the entire spectrum of ankylosing spondylitis (AS)/axial spondyloarthritis (AxSpA).
Language
English
Standards
| Standard | Name | ID | Source |
|---|
Derived Variables
None
Process and Review
Not applicable.
Protocol Name from Source
Bath Ankylosing Spondylitis Disease Activity Index (BASDAI)
Source
Garrett, S., Jenkinson, T., Kennedy, L. G., Whitelock, H., Gaisford, P., & Calin, A. (1994). A new approach to defining disease status in ankylosing spondylitis: The Bath Ankylosing Spondylitis Disease Activity Index. Journal of Rheumatology, 21(12), 2286–2291.
General References
Auleley, G.-R., Benbouazza, K., Spoorenberg, A., Collantes, E., Hajjaj-Hassouni, N., van der Heijde, & Dougados, M. (2002). Evaluation of the smallest detectable difference in outcome or process variables in ankylosing spondylitis. Arthritis and Rheumatism, 47(6), 582–587.
Dougados, M., Luo, M. P., Maksymowych, W. P., Chmiel, J. J., Chen, N., Wong, R. L., . . . van der Heijde, D.; ATLAS Study Group. (2008). Evaluation of the patient acceptable symptom state as an outcome measure in patients with ankylosing spondylitis: Data from a randomized controlled trial. Arthritis and Rheumatism, 59(4), 553–560.
Kviatovsky, M. J., Ramiro, S., Landewé, R., Dougados, M., Tubach, F., Bellamy, N., . . . van der Heijde, D. (2016). Journal of Rheumatology, 43(9), 1680–1686.
Madsen, O. R., Rytter, A., Hansen, L. B., Suetta, C., & Egsmone, C. (2010). Reproducibility of the Bath Ankylosing Spondylitis Indices of disease activity (BASDAI), functional status (BASFI) and overall well-being (BAS-G) in anti-tumour necrosis factor-treated spondyloarthropathy patients. Clinical Rheumatology, 29(8), 849–854.
Maksymowych, W. P., Richardson, R., Mallon, C., van der Heijde, D., & Boonen, A. (2007). Evaluation and validation of the patient acceptable symptom state (PASS) in patients with ankylosing spondylitis. Arthritis and Rheumatism, 57(1), 133–139.
Ogdie, A., Duarte-García, A., Hwang, M., Navarro-Compán, V., van der Heijde, D., & Mease, P. (2020). Arthritis Care and Research (Hoboken), 72(Suppl. 20), 47–71.
Pavy, S., Brophy, S., & Calin, A. (2005). Establishment of the minimum clinically important difference for the bath ankylosing spondylitis indices. Journal of Rheumatology, 32(1), 80–85.
Song, I. H., Rudwaleit, M., Listing, J., & Sieper, J. (2009). Comparison of the Bath Ankylosing Spondylitis Disease Activity Index and a modified version of the index in assessing disease activity in patients with ankylosing spondylitis without peripheral manifestations. Annals of the Rheumatic Diseases, 68(11), 1701–1707.
Tubach, F., Pham, T., Skomsvoll, J. F., Mikkelsen, K., Bjorneboe, O., Ravaud, P., . . . Kvien, T. K. (2006). Stability of the patient acceptable symptomatic state over time in outcome criteria in ankylosing spondylitis. Arthritis and Rheumatism, 55(6), 960–963.
van Tubergen, A., Black, P. M., & Coteur, G. (2015). Are patient-reported outcome instruments for ankylosing spondylitis fit for purpose for the axial spondyloarthritis patient? A qualitative and psychometric analysis. Rheumatology (Oxford), 54(10), 1842–1851.
van Tubergen, A., Debats, I., Ryser, L., Londoño, J., Burgos-Vargas, R., Cardiel, M. H., . . . van der Heijde, D. (2002). Use of a numerical rating scale as an answer modality in ankylosing spondylitis–specific questionnaires. Arthritis and Rheumatism, 47(3), 242–248.
Protocol ID
171101
Variables
Export Variables| Variable Name | Variable ID | Variable Description | dbGaP Mapping | |
|---|---|---|---|---|
| PX171101_Axial_Spondyloarthritis_Length_Morning_Stiffness_Last | ||||
| PX171101060000 | How long does your morning stiffness last more | N/A | ||
| PX171101_Axial_Spondyloarthritis_Overall_Level_Discomfort_Areas_Tender_Touch_Pressure | ||||
| PX171101040000 | How would you describe the overall level of more | N/A | ||
| PX171101_Axial_Spondyloarthritis_Overall_Level_Fatigue_Tiredness | ||||
| PX171101010000 | How would you describe the overall level of more | N/A | ||
| PX171101_Axial_Spondyloarthritis_Overall_Level_Morning_Stiffness | ||||
| PX171101050000 | How would you describe the overall level of more | N/A | ||
| PX171101_Axial_Spondyloarthritis_Overall_Level_Neck_Back_Hip_Pain | ||||
| PX171101020000 | How would you describe the overall level of more | N/A | ||
| PX171101_Axial_Spondyloarthritis_Overall_Level_Pain_Swelling_Joints_Not_Neck_Back_Hip | ||||
| PX171101030000 | How would you describe the overall level of more | N/A | ||
Measure Name
Axial Spondyloarthritis (AxSpA)/Ankylosing Spondylitis (AS)
Release Date
October 21, 2022
Definition
A questionnaire used to measure patient-reported disease activity in patients with axial spondyloarthritis (AxSpA), which includes the subsets of patients with non-radiographic AxSpA and radiographic AxSpA (also known as AS).
Purpose
Ongoing monitoring and assessment of change in disease activity is key to appropriate care and treatment for patients with ankylosing spondylitis (AxSpA).
Keywords
Ankylosing spondylitis, AS, axial spondyloarthritis, AxSpA, Bath Ankylosing Spondylitis Disease Activity Index, BASDAI, bone and joint
Measure Protocols
| Protocol ID | Protocol Name |
|---|---|
| 171101 | Axial Spondyloarthritis (AxSpA) |
Publications
There are no publications listed for this protocol.