Protocol - Knee Pain - Past 30 Days
A self-report, three-item series of questions with answer choices for “Yes,” “No,” and “Don’t know.”
If question 1 is answered “No” or “Don’t know/Refused,” do not ask questions 1a or 1b. After question number 1, go to 1a and 1b if “Yes.” If the response is “No” to 1a, you should still go to 1b.
The phrase “During the past 30 days, have you had pain,,, “on most days” indicates pain on 15 or more days out of 30. However, a precise number is not needed. This applies to 1a and 1b.
Although the original questions were administered in a telephone interview, it would be better administered during an interview (to reduce confusion on the part of the subject). The PhenX Bone and Joint Working Group suggests that they may be used as self-administered items. For self-administration, the interviewer needs to introduce it and go over the instructions with the subject and allow subject to then complete.
The MOST datasets can only be obtained through the National Institute on Aging (NIA) Biobank. Those wishing to obtain the MOST datasets please go to the NIH Biobank website at: https://agingresearchbiobank.nia.nih.gov/studies/most/
1. During the past 30 days, have you had any pain, aching or stiffness in or around either knee?
[ ] 1 Yes (Go to 1a & 1b)
[ ] 0 No
[ ] 8 Don’t know/Refused
1a. During the past 30 days, have you had pain, aching or stiffness in or around your right knee on most days?
[ ] 1 Yes
[ ] 0 No
[ ] 8 Don’t know
1b. During the past 30 days, have you had pain, aching or stiffness in or around your left knee on most days?
[ ] 1 Yes
[ ] 0 No
[ ] 8 Don’t know
Personnel and Training Required
The interviewer must be trained to conduct personal interviews with individuals. The interviewer must be trained and found to be competent (i.e., tested by an expert) at the completion of personal interviews. The interviewer should be trained to prompt respondents further if a “Don’t know” response is provided.
|Specialized requirements for biospecimen collection||No|
|Average time of greater than 15 minutes in an unaffected individual||No|
Mode of Administration
Older Americans, men and women aged 50–79 with knee osteoarthritis or at increased risk of developing it. Some of these could be used in a more general population but may not have the same validity. Many in MOST and the Osteoarthritis Initiative (OAI) had no knee symptoms and it worked fine there. This set of questions has also been used in Framingham, a community-based cohort of adults aged 30 and over, mostly without knee pain.
The Multicenter Osteoarthritis Study (MOST) is a longitudinal, prospective, observational study of knee osteoarthritis (OA) with validated, simple questionnaires.
Process and Review
Protocol Name from Source
Multicenter Osteoarthritis Study (MOST) Baseline Telephone Screening Interview, Screening visit, 2003, Grant cycles 1 & 2.
Segal, N. A., Nevitt, M. C., Gross, K. D., Hietpas, J., Glass, N. A., Lewis, C. E., & Torner, J. C. (2013). The Multicenter Osteoarthritis Study: Opportunities for rehabilitation research. PM&R, 5(8), 647–654. https://doi.org/10.1016/j.pmrj.2013.04.014.
Carlesso, L. C., Law, L. F., Wang, N., Nevitt, M., Lewis, C. E., & Neogi, T.; Multicenter Osteoarthritis Study Group. (2022).Association of pain sensitization and conditioned pain modulation to pain patterns in knee osteoarthritis. Arthritis Care & Research, 74(1), 107–112. https://doi.org/10.1002/acr.24437
National Institute on Aging. (2021). MOST public data release: Annotated data collection forms: Baseline dataset. AgingResearch Biobank. https://agingresearchbiobank.nia.nih.gov/studies/most/documents/download/Forms/AnnotatedForms_Baseline.pdf/
Perry, T. A., Segal, N. A., Bowen, C., Gates, L., Arden, N., & Nevitt, M. C. (2021). Foot and ankle pain and risk of incident knee osteoarthritis and knee pain: Data from the Multicentre Osteoarthritis Study. Osteoarthritis and Cartilage Open, 3(4), 100210. https://doi.org/10.1016/j.ocarto.2021.100210
|Variable Name||Variable ID||Variable Description||dbGaP Mapping|
|PX171501010000||During the past 30 days, have you had any more||N/A|
|PX171501010200||During the past 30 days, have you had pain, more||N/A|
|PX171501010100||During the past 30 days, have you had pain, more||N/A|
Knee Pain - Past 30 Days
October 21, 2022
A questionnaire assessing knee pain in the last 30 days.
This is a screener for knee pain, which is major cause of activity limitation and physical disability in older people.
knee pain - past 30 days, pain, disability index, foot pain, knee injury, osteoarthritis, walking-ambulation objective measure
|Protocol ID||Protocol Name|
|171501||Knee Pain - Past 30 Days|
There are no publications listed for this protocol.