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Protocol - Alcohol - Lifetime Use

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Description

Measurement of whether respondent has ever consumed alcohol.

Specific Instructions

Alcohol is defined as any type of alcohol (including coolers, beer, wine, champagne) and liquor (e.g., whiskey, rum, gin, vodka, scotch, or liqueurs).

Availability

Available

Protocol

The Working Group acknowledges that the following question may gather sensitive information relating to the use of substances and/or illegal conduct. If the information is released it might be damaging to an individual’s employability, lead to social stigmatization, or other consequences.

For information on obtaining a Certificate of Confidentiality, which helps researchers protect the privacy of human research participants, please go to the National Human Genome Research Institute’s Institutional Review Board website.

The following question is asked of the respondent. Respondents answer yes or no to this question. Read the introductory paragraph to the respondent. If your questionnaire includes multiple questions about alcohol, then the first sentence should be "The next questions are about drinking alcohol."

The next question is about drinking alcohol. This includes coolers, beer, wine, champagne, liquor such as whiskey, rum, gin, vodka, scotch, or liqueurs, and also any other type of alcohol.

In your entire life, have you had at least 1 drink of any kind of alcohol, not counting small tastes or sips?

1[ ]Yes

2[ ]No

Notes to interviewer:

  • Definition of a standard drink: 1 12oz bottle of beer, 1 glass 4oz non-fortified wine, 1 mixed drink with 1oz liquor.
  • If respondent needs a visual reference for the size of a drink, the flashcards from the Wave 1 National Epidemiologic Survey on Alcohol and Related Conditions (NESARC) study are provided below:

Personnel and Training Required

Interviewer must be trained and found to be competent to conduct personal interviews with individuals from the general population. The interviewer should be trained to prompt respondents further if a "don’t know" response is provided.

Equipment Needs

While the Alcohol Use Disorder and Associated Disabilities Interview Schedule-IV (AUDADIS-IV) instrument was developed for administration by computer, the PhenX Working Group acknowledges that this question can be administered in a noncomputerized format. Hasin et al. (1997) and Grant et al. (1995) used the AUDADIS in paper-and-pencil format, while Grant et al. (2003) obtained data with the computerized format.

Requirements
Requirement CategoryRequired
Major equipment No
Specialized training No
Specialized requirements for biospecimen collection No
Average time of greater than 15 minutes in an unaffected individual No
Mode of Administration

Interviewer-administered questionnaire

Lifestage

Adult

Participants

≥18 years of age

Selection Rationale

The protocol from the Alcohol Use Disorder and Associated Disabilities Interview Schedule (AUDADIS) was chosen because it was used in a large epidemiological study of adults of a wide age range and different ethnicities (Wave 1 included 43,093 Americans; in Wave 2, 34,653 members of the original cohort were reinterviewed). The measures from this survey have been validated and psychometrically tested.

Language

Chinese, English, Other languages available at source

Standards
StandardNameIDSource
Logical Observation Identifiers Names and Codes (LOINC) Alcohol lifetime use proto 62543-4 LOINC
Human Phenotype Ontology Alcoholism HP:0030955 HPO
caDSR Form PhenX PX030101 - Alcohol Lifetime Use 5806376 caDSR Form
Derived Variables

None

Process and Review

The Expert Review Panel #3 (ERP 3) reviewed the measures in Alcohol, Tobacco and Other Substances, and Substance Abuse and Addiction domains.

Guidance from ERP 3 includes:

• No significant changes to measure

Back-compatible: NA no changes to Data Dictionary

Previous version in Toolkit archive (link)

Protocol Name from Source

National Epidemiologic Survey on Alcohol and Related Conditions (NESARC), Wave 1

Source

National Institute on Alcohol Abuse and Alcoholism (NIAAA) National Epidemiologic Survey on Alcohol and Related Conditions. Wave 1 (NESARC - WAVE 1). Alcohol Use Disorder and Associated Disabilities Interview Schedule - Diagnostic and Statistical Manual of Mental Disorders. Fourth Edition Version (AUDADIS-IV). Section 2A. Question 1 and Flashcard Booklet, Flashcards 13A-C, 16A-C, and 17A-C.

Grant, B. F., Dawson, D. A., Stinson, F. S., Chou, P. S., Kay, W., & Pickering, R. (2003) The Alcohol Use Disorder and Associated Disabilities Interview Schedule-IV (AUDADIS-IV): Reliability of alcohol consumption, tobacco use, family history of depression and psychiatric diagnostic modules in a general population sample. Drug and Alcohol Dependence, 71(1), 7-16.

General References

Grant, B. F., Dawson, D. A., Stinson, F. S., Chou, P. S., Kay, W., & Pickering R. (2003). The Alcohol Use Disorder and Associated Disabilities Interview Schedule-IV (AUDADIS-IV): Reliability of alcohol consumption, tobacco use, family history of depression and psychiatric diagnostic modules in a general population sample. Drug and Alcohol Dependence, 71(1), 7-16.

Grant, B. F., Harford, T. C., Dawson, D. A., Chou, P. S., & Pickering, R. P. (1995). The Alcohol Use Disorder and Associated Disabilities Interview Schedule (AUDADIS): Reliability of alcohol and drug modules in a general population sample. Drug and Alcohol Dependence, 39(1), 37-44.

Hasin, D., Carpenter, K. M., McCloud, S., Smith, M., & Grant, B. F. (1997). The Alcohol Use Disorder and Associated Disabilities Interview Schedule (AUDADIS): Reliability of alcohol and drug modules in a clinical sample. Drug and Alcohol Dependence, 44(2-3), 133-141.

For information regarding alcohol consumption among women who are pregnant, please refer to the Centers for Disease Control and Prevention (CDC) National Center on Birth Defects & Developmental Disabilities Fetal Alcohol Syndrome website, the CDC Behavioral Risk Factor Surveillance System website, and the CDC Pregnancy Risk Assessment Monitoring System (PRAMS) website.

Protocol ID

30101

Variables
Export Variables
Variable Name Variable IDVariable DescriptiondbGaP Mapping
PX030101_Lifetime_Use
PX030101010000 In your entire life, have you had at least 1 more
drink of any kind of alcohol, not counting small tastes or sips? show less
N/A
Alcohol, Tobacco and Other Substances
Measure Name

Alcohol - Lifetime Use

Release Date

February 6, 2009

Definition

Question asking the respondent if s/he has ever consumed any alcoholic beverage during his or her entire life.

Purpose

This measure can be used to assess the participant’s lifetime exposure to alcohol. The question is often used as a prelude to more detailed questions about alcohol use to screen out individuals who have ever consumed alcohol.

Keywords

alcohol, alcohol exposure, alcohol use, alcohol abuse, alcohol use, coolers, beer, wine, champagne, liquor, whiskey, rum, gin, vodka, scotch, liqueurs, sherry, cocktail, mixed drink, National Institute on Alcohol Abuse and Alcoholism, NIAAA, National Epidemiologic Survey on Alcohol and Related Conditions, NESARC, Alcohol Use Disorder and Associated Disabilities Interview Schedule, AUDADIS, Diagnostic and Statistical Manual of Mental Disorders, National Survey on Drug Use and Health, NSDUH, gerontology, aging, geriatrics

Measure Protocols
Protocol ID Protocol Name
30101 Alcohol - Lifetime Use
Publications

Barbirou, M., et al. (2020) Western influenced lifestyle and Kv2.1 association as predicted biomarkers for Tunisian colorectal cancer. BMC Cancer. 2020 November; 20: Article Number: 1086. doi: 10.1186/s12885-020-07605-7

Wu, Y., et al. (2020) Short-term exposure to air pollution and its interaction effects with two ABO SNPs on blood lipid levels in northern China: A family-based study. Chemosphere. 2020 June; 249: 8. doi: 10.1016/j.chemosphere.2020.126120

Kwok, R. K., et al. (2017) The GuLF STUDY: A Prospective Study of Persons Involved in the Deepwater Horizon Oil Spill Response and Clean-Up. Environ Health Perspect. 2017 April; 125(4): 570-578. doi: 10.1289/EHP715

Salmoirago-Blotcher, E., et al. (2017) Phone-delivered mindfulness training to promote medication adherence and reduce sexual risk behavior among persons living with HIV: Design and methods. Contemp Clin Trials. 2017 February; 53: 162-170. doi: 10.1016/j.cct.2016.12.016

McCarty, C.A., Berg, R., Rottscheit, C.M., Waudby, C.J., Kitchner, T., Brilliant, M., Ritchie, M.D. (2014) Validation of PhenX measures in the personalized medicine research project for use in gene/environment studies. BMC Med Genomics. 2014 January; 7: 3. doi: 10.1186/1755-8794-7-3