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Protocol - Family History of Heart Attack

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Description:

This measure assesses if the respondent's biological parents, siblings, and children have had a heart attack.

Protocol:

For these questions, please think about full-blooded relatives only. Do not think about half-sisters or half-brothers, or relatives who are related to you by marriage or adoption. Full-blooded sisters and brothers are those who had the same two parents as you. If you are adopted or are not sure about some relatives' health history, please include any family history that you know about.

1. Did your mother, father, full-blooded sisters, full-blooded brothers, daughters, or sons ever have a heart attack or myocardial infarction?

[] 0 No

[] 1 Yes

[] 9 Don't Know

If Yes, continue to 2. If No or Don't Know, end of protocol.

Please answer the following questions for each of your relatives, starting with those who had a heart attack. If you do not have a full-blooded sister, full-blooded brother, daughter, or son, leave the spaces blank.

2. Did this relative have a heart attack?

No
(0)
Yes
How old was he or she when the first heart attack occurred?
Don't know if he or she had a heart attack
(9)
Less than 55
(1)
55-64
(2)
65 or older
(3)
Don't know age
(4)
Mother
Father
Sister
Sister
Sister
Brother
Brother
Brother
Daughter
Daughter
Son
Son

Diagnostic Criteria:

The definition of a positive family history of coronary heart disease is father, brother, or son with coronary disease onset at age <55 years and mother, sister, or daughter with coronary disease onset at age <65 years.

Protocol Name from Source:

The Expert Review Panel has not reviewed this measure yet.

Availability:

Publicly available

Personnel and Training Required

An interviewer who is trained to conduct personal interviews with individuals from the general population is required. The interviewer must be trained and found to be competent (i.e., tested by an expert) at the completion of personal interviews.* The interviewer should be trained to prompt respondents further if a "don't know" response is provided.

* There are multiple modes to administer this question (e.g., paper-and-pencil and computer-assisted interviews).

Equipment Needs

None

Requirements
Requirement CategoryRequired
Major equipment No
Specialized training No
Specialized requirements for biospecimen collection No
Average time of greater than 15 minutes in an unaffected individual No
Mode of Administration

Interviewer-administered questionnaire

Life Stage:

Adult

Participants:

Women ages 50–79 years old

Note: This protocol has been reliably used with women ages 50–79 years old. However, the Cardiovascular Working Group suggests that the same methodology be used for men and women below age 50 years old.

Specific Instructions:

If the respondent answers "yes" to the first question, then the interviewer will proceed to the next question, which asks about history of heart attack for specific biological relatives.

Selection Rationale

This protocol was selected because it obtains the age at which the heart attack occurred, which is a vital part of identifying a positive family history. It was also used on a major U.S. health study and captures a thorough picture of family history through the inclusion of several family member categories (i.e., mother, father, sisters, brothers, daughters, sons).

Language

English, Spanish

Standards
StandardNameIDSource
Common Data Elements (CDE) Person Family Medical History Myocardial Infarction Indicator 2935311 CDE Browser
Logical Observation Identifiers Names and Codes (LOINC) Fam hx heart attack proto 62390-0 LOINC
Process and Review

The Expert Review Panel has not reviewed this measure yet.

Source

U.S. Department of Health and Human Services. National Institutes of Health. National Heart, Lung and Blood Institute. Women's Health Initiative (WHI). Form 32&emdash;Family History Questionnaire. Version 3. Page 4. Question 8 (source for questions 1 and 2 in Protocol Text).

National Cholesterol Education Program (NCEP) Adult Treatment Panel (ATP) III Guidelines. http://www.nhlbi.nih.gov/guidelines/cholesterol/atp3full.pdf (source for Diagnostic Criteria).

General References

None

Protocol ID:

40101

Variables:
Export Variables
Variable NameVariable IDVariable DescriptionVersiondbGaP Mapping
PX040101_Brother_1_Heart_Attack_History PX040101020600 Did your brother have a heart attack? 4 N/A
PX040101_Brother_2_Heart_Attack_History PX040101020700 Did your brother have a heart attack? 4 N/A
PX040101_Brother_3_Heart_Attack_History PX040101020800 Did your brother have a heart attack? 4 N/A
PX040101_Daughter_1_Heart_Attack_History PX040101020900 Did your daughter have a heart attack? 4 N/A
PX040101_Daughter_2_Heart_Attack_History PX040101021000 Did your daughter have a heart attack? 4 N/A
PX040101_Family_Ever_Have_Heart_Attack PX040101010000 Did your mother, father, full-blooded sisters, full-blooded brothers, daughters, or sons ever have a heart attack or myocardial infarction? 4 N/A
PX040101_Father_Heart_Attack_History PX040101020200 Did your father have a heart attack? 4 N/A
PX040101_Mother_Heart_Attack_History PX040101020100 Did your mother have a heart attack? 4 N/A
PX040101_Sister_1_Heart_Attack_History PX040101020300 Did your sister have a heart attack? 4 N/A
PX040101_Sister_2_Heart_Attack_History PX040101020400 Did your sister have a heart attack? 4 N/A
PX040101_Sister_3_Heart_Attack_History PX040101020500 Did your sister have a heart attack? 4 N/A
PX040101_Son_1_Heart_Attack_History PX040101021100 Did your son have a heart attack? 4 N/A
PX040101_Son_2_Heart_Attack_History PX040101021200 Did your son have a heart attack? 4 N/A
Research Domain Information
Measure Name:

Family History of Heart Attack

Release Date:

September 9, 2009

Definition

Measure to assess whether respondent's biological parents, siblings, and children have had a heart attack.

Purpose

Family history is used to assess the presence and age of onset of heart attack in all first-degree relatives. A positive family history for heart attack in a first-degree relative (parent, siblings, or offspring) at a relatively young age is a major risk factor for coronary heart disease.

Keywords

Cardiovascular, Women's Health Initiative, WHI, National Cholesterol Education Program, NCEP, Heart attack, myocardial infarction, coronary heart disease, CHD, cardiovascular disease, cardiovascular, Family History, Family History of Heart Attack