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Protocol - Substance Abuse and Dependence - Past Year - Alcohol

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Description

In a face-to-face interview, the respondent is asked several questions about alcohol abuse and dependence during the past 12 months. These responses correspond with criteria from the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5). The questions encompass marijuana and several prescription and other illicit drug categories.

Specific Instructions

The Alcohol Use Disorder and Associated Disabilities Interview Schedule-Diagnostic and Statistical Manual of Mental Disorders-Fifth Edition Version (AUDADIS-5) Alcohol and Drug Use Disorders Scoring Algorithms are provided for data interpretation. Please click here to access the scoring algorithm document. The algorithms were constructed by Yoanna McDowell, M.A, under the supervision of Dr. Kenneth Sher (University of Missouri) in 2017 and posted here with their permission. They were verified by diagnostic variables available in the NESARC-III data set and published NESARC-III diagnostic and severity prevalence data. Users are solely responsible for the use and interpretation of the algorithms and results.

Due to the complexity of the algorithms and associated analysis, Expert Review Panel 3 recommends analysis be performed by a statistician who has experience using NESARC datasets,

The Alcohol Use Disorder and Associated Disabilities Interview Schedule-Diagnostic and Statistical Manual of Mental Disorders-Fifth Edition Version (AUDADIS-5) is a complex diagnostic instrument that likely requires expertise with SAS and the NESARC dataset in order to successfully implement scoring algorithms. Investigators interested in briefer, screening-level assessments of alcohol and other substance use disorders are encouraged to review assessments of this collection:

http://grants1.nih.gov/grants/policy/coc/index.htm).

Availability

Available

Protocol

1b. Did this happen in the last 12 months?

(1) Find that your usual number of drinks had much less effect on you than it once did?

1 [ ] Yes

2 [ ] No

(2) Find that you had to drink much more than you once did to get the effect you wanted?

1 [ ] Yes

2 [ ] No

(3) Drink as much as a fifth of liquor in one day, that would be about 20 drinks, or 3 bottles of wine, or as much as 3 six-packs of beer in a single day?

1 [ ] Yes

2 [ ] No

(4) Increase your drinking because the amount you used to drink didn’t give you the same effect anymore?

1 [ ] Yes

2 [ ] No

(5) More than once WANT to stop or cut down on your drinking?

1 [ ] Yes

2 [ ] No

(6) More than once TRY to stop or cut down on your drinking but found you couldn’t do it?

1 [ ] Yes

2 [ ] No

(7) Have a period when you ended up drinking more than you meant to?

1 [ ] Yes

2 [ ] No

(8) Have a period when you kept on drinking for longer than you had intended to?

1 [ ] Yes

2 [ ] No

The next few questions are about the bad aftereffects of drinking that people may have when the effects of alcohol are wearing off. This includes the morning after drinking or in the first few days after stopping or cutting down.

(9) Have trouble falling asleep or staying asleep (when the effects of alcohol were wearing off)?

1 [ ] Yes

2 [ ] No

(10) Find yourself shaking or your hands trembling?

1 [ ] Yes

2 [ ] No

(11) Feel anxious or nervous?

1 [ ] Yes

2 [ ] No

(12) Feel sick to your stomach or vomit (when the effects of alcohol were wearing off)?

1 [ ] Yes

2 [ ] No

(13) Feel more restless than is usual for you?

1 [ ] Yes

2 [ ] No

(14) Find yourself sweating or your heart beating fast?

1 [ ] Yes

2 [ ] No

(15) See, feel, or hear things that weren’t really there (when the effects of alcohol were wearing off)?

1 [ ] Yes

2 [ ] No

(16) Have fits or seizures?

1 [ ] Yes

2 [ ] No

Check Item 2.11

Are at least 2 items marked "Yes" in column b, items 9-16

1 [ ] Yes

2 [ ] No - SKIP to Check Item 2.12

(17) You just mentioned that you had SOME bad aftereffects when stopping or cutting down on drinking in the last 12 months. Did at least 2 of these experiences happen around the same time DURING the last 12 months?

1 [ ] Yes

2 [ ] No

1b. Did this happen in the last 12 months?

(18) Take a drink or use any drug or medicine, other than aspirin, Advil or Tylenol, to GET OVER any of the bad aftereffects of drinking?

1 [ ] Yes

2 [ ] No

(19) Take a drink or use any drug or medicine, other than aspirin, Advil or Tylenol, to KEEP FROM having any of these bad aftereffects of drinking?

1 [ ] Yes

2 [ ] No

(20) Have a period when you spent a lot of time drinking?

1 [ ] Yes

2 [ ] No

(21) Have a period when you spent a lot of time being sick or getting over the bad aftereffects of drinking?

1 [ ] Yes

2 [ ] No

(22) Give up or cut down on activities that were important to you in order to drink-like work, school, or associating with friends or relatives?

1 [ ] Yes

2 [ ] No

(23) Give up or cut down on activities that you were interested in or that gave you pleasure in order to drink?

1 [ ] Yes

2 [ ] No

(24) Continue to drink even though you knew it was making you feel depressed, uninterested in things, or suspicious or distrustful of other people?

1 [ ] Yes

2 [ ] No

(25) Continue to drink even though you knew it was causing you a health problem or making a health problem worse?

1 [ ] Yes

2 [ ] No

(26) Continue to drink even though you had experienced a prior blackout, that is, awakened the next day not being able to remember some of the things you did while drinking or after drinking?

1 [ ] Yes

2 [ ] No

(27) Feel a very strong urge or desire to drink?

1 [ ] Yes

2 [ ] No

(28) Want a drink so badly that you couldn’t think of anything else?

1 [ ] Yes

2 [ ] No

(29) Have a period when your drinking or being sick from drinking often interfered with taking care of your home or family?

1 [ ] Yes

2 [ ] No

(30) Have job or school troubles because of your drinking or being sick from drinking-like missing too much work, not doing your work well, being demoted or losing a job, or being suspended, expelled, or dropping out of school?

1 [ ] Yes

2 [ ] No

(31) Continue to drink even though it was causing you problems at school or at work?

1 [ ] Yes

2 [ ] No

(32) More than once drive a car or other vehicle WHILE you were drinking?

1 [ ] Yes

2 [ ] No

(33) Drive a car, motorcycle, truck, boat, or other vehicle and have an accident WHILE you were under the influence of alcohol?

1 [ ] Yes

2 [ ] No

(34) More than once drive a car, motorcycle, truck, boat, or other vehicle AFTER having too much to drink?

1 [ ] Yes

2 [ ] No

(35) Get into situations while drinking or after drinking that increased your chances of getting hurt-like swimming, using machinery, or walking in a dangerous area or around heavy traffic?

1 [ ] Yes

2 [ ] No

(36) Have arguments or problems with your spouse or partner or family or friends because of your drinking?

1 [ ] Yes

2 [ ] No

(37) Continue to drink even though it was causing you trouble with your family or friends?

1 [ ] Yes

2 [ ] No

(38) Get into physical fights while drinking or right after drinking?

1 [ ] Yes

2 [ ] No

3b. Did this happen in the last 12 months?

(2) Ride in a car as a passenger while you were drinking?

1 [ ] Yes

2 [ ] No

(3) Drive a car, motorcycle, truck, or other vehicle and injure yourself or someone else in an accident while you were under the influence of alcohol?

1 [ ] Yes

2 [ ] No

(4) Accidentally injure yourself or someone else in any way other than motor vehicle accidents, like a bad fall or bad cut, while you were under the influence of alcohol?

1 [ ] Yes

2 [ ] No

(5) More than once get arrested, held at a police station, or have any other legal problems because of your drinking?

1 [ ] Yes

2 [ ] No

(6) Ride in a car or other vehicle WHILE the driver was drinking?

1 [ ] Yes

2 [ ] No

Personnel and Training Required

The interviewer must be trained and found competent to conduct personal interviews with individuals from the general population. The interviewer should be trained to prompt respondents further if a "don’t know" response is provided. It is preferable either to read the questionnaire aloud to the respondent or to administer it in an audio-assisted computer interview (ACASI) format. The questions are sensitive in nature, and the interviewer should be trained to react appropriately to emotional responses. If a distressed respondent protocol is adopted, the interviewer should be trained to administer those procedures.

Equipment Needs

While the Alcohol Use Disorder and Associated Disabilities Interview Schedule-5 (AUDADIS-5) instrument was developed for administration by computer, the PhenX WG acknowledges that these questions can be administered in a noncomputerized format. Hasin et al. (1997) and Grant et al. (1995) used the AUDADIS in paper-and-pencil format, while Grant et al. (2003) obtained data with the computerized format.

Requirements
Requirement CategoryRequired
Major equipment No
Specialized training No
Specialized requirements for biospecimen collection No
Average time of greater than 15 minutes in an unaffected individual No
Mode of Administration

Interviewer-administered questionnaire

Lifestage

Adult

Participants

Adults aged 18 years or older

Selection Rationale

The National Epidemiologic Survey on Alcohol and Related Conditions-III (NESARC-III) captures "diagnostic" information via the Alcohol use Disorder and Associated Disabilities Interview Schedule-5 (AUDADIS-5). Therefore, the user can link diagnostic data from the NESARC directly to treatment utilization also collected from the NESARC.

Language

English

Standards
StandardNameIDSource
Human Phenotype Ontology Addictive behavior HP:0030858 HPO
caDSR Form PhenX PX510404 - Substance Abuse And Dependence Past Year Alcohol 6882520 caDSR Form
Derived Variables

None

Process and Review

The Expert Review Panel #3 (ERP3) reviewed the measures in the Alcohol, Tobacco and Other Substances domain, and the Substance Abuse and Addiction Collection.

Guidance from the ERP includes:

  • Updated protocol (same source)

Partially back-compatible (updated/similar protocol which would require some changes to the data dictionary), variable mapping between current and previous protocols can be found here (link)

Protocol Name from Source

National Institute on Alcohol Abuse and Alcoholism (NIAAA), National Epidemiologic Survey on Alcohol and Related Conditions-III (NESARC-III)

Source

National Institute on Alcohol Abuse and Alcoholism (NIAAA). (N.d.). National Epidemiologic Survey on Alcohol and Related Conditions-III (NESARC-III). Rockville, MD: National Institutes of Health. Alcohol use Disorder and Associated Disabilities Interview Schedule-5 (AUDADIS-5), Section 2B - Alcohol Experiences (Questions 1b and 3b).

General References

Grant, B. F., Dawson, D. A., Stinson, F. S., Chou, P. S., Kay, W., & Pickering, R. (2003). The Alcohol Use Disorder and Associated Disabilities Interview Schedule-IV (AUDADIS-IV): Reliability of alcohol consumption, tobacco use, family history of depression and psychiatric diagnostic modules in a general population sample. Drug and Alcohol Dependence, 71(1), 7-16.

Grant, B. F., Goldstein, R. B., Smith, S. M., Jung, J., Zhang, H., Chou, S. P., Pickering, R. P., Ruan, W. J., Huang, B., Saha, T. D., Aivadyan, C., Greenstein, E., & Hasin, D. S. (2015). The Alcohol Use Disorder and Associated Disabilities Interview Schedule-5 (AUDADIS-5): Reliability of substance use and psychiatric disorder modules in a general population sample. Drug and Alcohol Dependence, 148, 27-33.

Grant, B. F., Harford, T. C., Dawson, D. A., Chou, P. S., & Pickering, R. P. (1995). The Alcohol Use Disorder and Associated Disabilities Interview Schedule (AUDADIS): Reliability of alcohol and drug modules in a general population sample. Drug and Alcohol Dependence, 39(1), 37-44.

Hasin, D., Carpenter, K. M., McCloud, S., Smith, M., & Grant, B. F. (1997). The Alcohol Use Disorder and Associated Disabilities Interview Schedule (AUDADIS): Reliability of alcohol and drug modules in a clinical sample. Drug and Alcohol Dependence, 44(2-3), 133-141.

Protocol ID

510404

Variables
Export Variables
Variable Name Variable IDVariable DescriptiondbGaP Mapping
PX510404_Substance_Abuse_Dependence_Past_Year_After_Effects_Prevention_Drugs
PX510404190000 Did you take a drink or use any drug or more
medicine, other than aspirin, advil or tylenol, to keep from having any of these bad aftereffects of drinking in the last 12 months? show less
N/A
PX510404_Substance_Abuse_Dependence_Past_Year_After_Effects_Recover_Drugs
PX510404180000 Did you take a drink or use any drug or more
medicine, other than aspirin, advil or tylenol, to get over any of the bad aftereffects of drinking in the last 12 months? show less
N/A
PX510404_Substance_Abuse_Dependence_Past_Year_After_Effects_Stop_Drinking
PX510404170200 You just mentioned that you had SOME bad more
aftereffects when stopping or cutting down on drinking in the last 12 months. Did at least 2 of these experiences happen around the same time DURING the last 12 months? show less
N/A
PX510404_Substance_Abuse_Dependence_Past_Year_Anxious_Nervous
PX510404110000 Did you feel anxious or nervous in the last more
12 months? show less
N/A
PX510404_Substance_Abuse_Dependence_Past_Year_Arrested_Multple_Times_Drinking
PX510404420000 Did you more than once get arrested, held at more
a police station, or have any other legal problems because of your drinking in the last 12 months? show less
N/A
PX510404_Substance_Abuse_Dependence_Past_Year_Continue_Drinking_Blackout
PX510404260000 Did you continue to drink even though you more
had experienced a prior blackout, that is, awakened the next day not being able to remember some of the things you did while drinking or after drinking in the last 12 months? show less
N/A
PX510404_Substance_Abuse_Dependence_Past_Year_Continue_Drinking_Depressed
PX510404240000 Did you continue to drink even though you more
knew it was making you feel depressed, uninterested in things, or suspicious or distrustful of other people in the last 12 months? show less
N/A
PX510404_Substance_Abuse_Dependence_Past_Year_Continue_Drinking_Family_Impact
PX510404370000 Did you continue to drink even though it was more
causing you trouble with your family or friends in the last 12 months? show less
N/A
PX510404_Substance_Abuse_Dependence_Past_Year_Continue_Drinking_Health
PX510404250000 Did you continue to drink even though you more
knew it was causing you a health problem or making a health problem worse in the last 12 months? show less
N/A
PX510404_Substance_Abuse_Dependence_Past_Year_Continue_Drinking_School_Work
PX510404310000 Did you continue to drink even though it was more
causing you problems at school or at work in the last 12 months? show less
N/A
PX510404_Substance_Abuse_Dependence_Past_Year_Desire_Stop_Drinking
PX510404270000 Did you feel a very strong urge or desire to more
drink in the last 12 months? show less
N/A
PX510404_Substance_Abuse_Dependence_Past_Year_Drinking_More_Accidentally
PX510404070000 Did you have a period when you ended up more
drinking more than you meant to in the last 12 months? show less
N/A
PX510404_Substance_Abuse_Dependence_Past_Year_Drinking_More_Than_Intended
PX510404080000 Did you have a period when you kept on more
drinking for longer than you had intended to in the last 12 months? show less
N/A
PX510404_Substance_Abuse_Dependence_Past_Year_Drinks_Less_Effect
PX510404010000 Did you find that your usual number of more
drinks had much less effect on you than it once did in the last 12 months? show less
N/A
PX510404_Substance_Abuse_Dependence_Past_Year_Drink_More_Same_Effect
PX510404020000 Did you find that you had to drink much more more
than you once did to get the effect you wanted in the last 12 months? show less
N/A
PX510404_Substance_Abuse_Dependence_Past_Year_Drive_Car_Drinking
PX510404320000 Did you more than once drive a car or other more
vehicle while you were drinking in the last 12 months? show less
N/A
PX510404_Substance_Abuse_Dependence_Past_Year_Family_Impact_Drinking
PX510404290000 Did you have a period when your drinking or more
being sick from drinking often interfered with taking care of your home or family in the last 12 months? show less
N/A
PX510404_Substance_Abuse_Dependence_Past_Year_Fight_Drinking
PX510404380000 Did you get into physical fights while more
drinking or right after drinking in the last 12 months? show less
N/A
PX510404_Substance_Abuse_Dependence_Past_Year_Fits_Seizures
PX510404160000 Did you have fits or seizures in the last 12 more
months? show less
N/A
PX510404_Substance_Abuse_Dependence_Past_Year_Hallucination
PX510404150000 Did you see, feel, or hear things that more
weren't really there when the effects of alcohol were wearing off in the last 12 months? show less
N/A
PX510404_Substance_Abuse_Dependence_Past_Year_Hobbies_Impact_Drinking
PX510404230000 Did you give up or cut down on activities more
that you were interested in or that gave you pleasure in order to drink in the last 12 months? show less
N/A
PX510404_Substance_Abuse_Dependence_Past_Year_Increase_Drinking_Same_Effect
PX510404040000 Did you increase your drinking because the more
amount you used to drink didn't give you the same effect anymore in the last 12 months? show less
N/A
PX510404_Substance_Abuse_Dependence_Past_Year_Item_Check
PX510404170100 Are at least 2 items marked Yes in column b, more
items 9-16 show less
N/A
PX510404_Substance_Abuse_Dependence_Past_Year_Job_School_Drinking
PX510404300000 Did you have job or school troubles because more
of your drinking or being sick from drinking-like missing too much work, not doing your work well, being demoted or losing a job, or being suspended, expelled, or dropping out of school in the last 12 month show less
N/A
PX510404_Substance_Abuse_Dependence_Past_Year_Passenger_Car_Drinking
PX510404390000 Did you ride in a car as a passenger while more
you were drinking in the last 12 months? show less
N/A
PX510404_Substance_Abuse_Dependence_Past_Year_Passenger_Car_Driver_Drinking
PX510404430000 Did you ride in a car or other vehicle while more
the driver was drinking in the last 12 months? show less
N/A
PX510404_Substance_Abuse_Dependence_Past_Year_Period_Drinking_Excessively
PX510404200000 Did you have a period when you spent a lot more
of time drinking in the last 12 months? show less
N/A
PX510404_Substance_Abuse_Dependence_Past_Year_Preoccupied_Drinking
PX510404280000 Did you want a drink so badly that you more
couldn't think of anything else in the last 12 months? show less
N/A
PX510404_Substance_Abuse_Dependence_Past_Year_Restless
PX510404130000 Did you feel more restless than is usual for more
you in the last 12 months? show less
N/A
PX510404_Substance_Abuse_Dependence_Past_Year_Safety_Risk_Drinking
PX510404350000 Did you get into situations while drinking more
or after drinking that increased your chances of getting hurt-like swimming, using machinery, or walking in a dangerous area or around heavy traffic in the last 12 months? show less
N/A
PX510404_Substance_Abuse_Dependence_Past_Year_Shaking_Trembling
PX510404100000 Did you find yourself shaking or your hands more
trembling in the last 12 months? show less
N/A
PX510404_Substance_Abuse_Dependence_Past_Year_Sick_Recovering_After_Effects_Drinking
PX510404210000 Did you have a period when you spent a lot more
of time being sick or getting over the bad aftereffects of drinking in the last 12 months? show less
N/A
PX510404_Substance_Abuse_Dependence_Past_Year_Sick_Vomit
PX510404120000 Did you feel sick to your stomach or vomit more
when the effects of alcohol were wearing off in the last 12 months? show less
N/A
PX510404_Substance_Abuse_Dependence_Past_Year_Social_Impact_Drinking
PX510404220000 Did you give up or cut down on activities more
that were important to you in order to drink-like work, school, or associating with friends or relatives in the last 12 months? show less
N/A
PX510404_Substance_Abuse_Dependence_Past_Year_Spouse_Fight_Drinking
PX510404360000 Did you have arguments or problems with your more
spouse or partner or family or friends because of your drinking in the last 12 months? show less
N/A
PX510404_Substance_Abuse_Dependence_Past_Year_Stop_Drinking_Multiple_Times
PX510404050000 Did you more than once want to stop or cut more
down on your drinking in the last 12 months? show less
N/A
PX510404_Substance_Abuse_Dependence_Past_Year_Stop_Drinking_Multiple_Times_Fail
PX510404060000 Did you more than once try to stop or cut more
down on your drinking but found you couldn't do it in the last 12 months? show less
N/A
PX510404_Substance_Abuse_Dependence_Past_Year_Sweating_Heart_Beating
PX510404140000 Did you find yourself sweating or your heart more
beating fast in the last 12 months? show less
N/A
PX510404_Substance_Abuse_Dependence_Past_Year_Trouble_Sleeping
PX510404090000 Did you have trouble falling asleep or more
staying asleep when the effects of alcohol were wearing off in the last 12 months? show less
N/A
PX510404_Substance_Abuse_Dependence_Past_Year_Twenty_Drinks
PX510404030000 Did you drink as much as a fifth of liquor more
in one day, that would be about 20 drinks, or 3 bottles of wine, or as much as 3 six-packs of beer in a single day in the last 12 months? show less
N/A
PX510404_Substance_Abuse_Dependence_Past_Year_Vehicle_Accident_Alcohol
PX510404400000 Did you drive a car, motorcycle, truck, or more
other vehicle and injure yourself or someone else in an accident while you were under the influence of alcohol in the last 12 months? show less
N/A
PX510404_Substance_Abuse_Dependence_Past_Year_Vehicle_Accident_Alcohol_Multiple_Times
PX510404340000 Did you more than once drive a car, more
motorcycle, truck, boat, or other vehicle after having too much to drink in the last 12 months? show less
N/A
PX510404_Substance_Abuse_Dependence_Past_Year_Vehicle_Accident_Injury
PX510404410000 Did you accidentally injure yourself or more
someone else in any way other than motor vehicle accidents, like a bad fall or bad cut, while you were under the influence of alcohol in the last 12 months? show less
N/A
PX510404_Substance_Abuse_Dependence_Past_Year_Vehicle_Accident_Under_Influence
PX510404330000 Did you drive a car, motorcycle, truck, more
boat, or other vehicle and have an accident while you were under the influence of alcohol in the last 12 months? show less
N/A
Assessment of Substance Use and Substance Use Disorders
Measure Name

Substance Abuse and Dependence - Past Year

Release Date

November 28, 2017

Definition

Interviewer-administered questions to determine whether the respondent has experienced symptoms of alcohol abuse and dependence, nicotine dependence, or substance abuse and dependence in the past year (i.e., past 12 months).

Purpose

This measure uses the 12-month criteria from the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5), to evaluate alcohol abuse and dependence, nicotine dependence, or substance abuse and dependence.

Keywords

Alcohol Use Disorder and Associated Disabilities Interview Schedule, AUDADIS, National Institute on Alcohol Abuse and Alcoholism, NIAAA, Diagnostic and Statistical Manual of Mental Disorder, DSM-5, National Epidemiologic Survey on Alcohol and Related Conditions, NESARC

Measure Protocols
Protocol ID Protocol Name
510403 Substance Abuse and Dependence - Past Year - Tobacco
510404 Substance Abuse and Dependence - Past Year - Alcohol
510405 Substance Abuse and Dependence - Past Year - Drugs
Publications

Dawes, K., et al. (2021) Epigenetic Analyses of Alcohol Consumption in Combustible and Non-Combustible Nicotine Product Users. Epigenomes. 2021 September; 5(3): 18. doi: 10.3390/epigenomes5030018