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Utilizing Interaction to Identify Novel Genetic Factors for Nicotine Dependence

Study Name Utilizing Interaction to Identify Novel Genetic Factors for Nicotine Dependence
Study Acronym
PI Dana Hancock, PhD
Funding Agency
Primary Contact Name Dana Hancock, PhD
Primary Contact Email dhancock@rti.org
Primary Research Focus This study aims to identify new genetic variants associated with nicotine dependence, by leveraging interactions with well-established variants from nicotinic acetylcholine receptor genes. To conduct this study, we have assembled >19,000 Caucasians and >4,000 African Americans, who all have genome-wide genotypes and Fagerstrom Test for Nicotine Dependence data, from our own cohorts and others from the database of Genotypes and Phenotypes (dbGaP). Results of this study may be used to better understand the genetic risk factors for nicotine dependence and smoking cessation and ultimately reduce the burden of smoking health consequences.
Study Design Name
Study Period 2013-2016
Number Participants >1000
Study Stage Name Funded
Study Website
Protocol Ids 310, 011, 070, 110, 101
Grant Number
Linked Date January 31, 2014 12:01AM
Citation Link