Protocol - Male Sexual Function
Description
The participant answers whether he has had difficulty with erections and sexual function during the past 4 weeks.
Specific Instructions
Note: At the recommendation of the PhenX Reproductive Health Working Group, the response categories in questions 1A-1D have been reversed from the original questions.
Note: These questions reference the past 4 weeks.
Protocol
1. How often did you have difficulty with any of the following?
A. Achieving an erection
1[ ]Almost never
2[ ]Sometimes
3[ ]Often
4[ ]Almost always
B. Ejaculating too early
1[ ]Almost never
2[ ]Sometimes
3[ ]Often
4[ ]Almost always
C. Difficulty ejaculating
1[ ]Almost never
2[ ]Sometimes
3[ ]Often
4[ ]Almost always
D. Lack of interest in sex
1[ ]Almost never
2[ ]Sometimes
3[ ]Often
4[ ]Almost always
2. Over the past four weeks how often were you able to get an erection during sexual activity?
0[ ]No sexual activity
1[ ]Almost never/never
2[ ]A few times (much less than half the time)
3[ ]Sometimes (about half the time)
4[ ]Most times (much more than half the time)
5[ ]Almost always/always
3. Over the past four weeks when you had erections with sexual stimulation, how often were your erections hard enough for penetration?
0[ ]No sexual activity
1[ ]Almost never/never
2[ ]A few times (much less than half the time)
3[ ]Sometimes (about half the time)
4[ ]Most times (much more than half the time)
5[ ]Almost always/always
4. Over the past four weeks when you attempted sexual intercourse, how often were you able to penetrate (enter) your partner?
0[ ]Did not attempt intercourse
1[ ]Almost never/never
2[ ]A few times (much less than half the time)
3[ ]Sometimes (about half the time)
4[ ]Most times (much more than half the time)
5[ ]Almost always/always
5. Over the past four weeks during sexual intercourse, how often were you able to maintain your erection after you had penetrated (entered) your partner?
0[ ]Did not attempt intercourse
1[ ]Almost never/never
2[ ]A few times (much less than half the time)
3[ ]Sometimes (about half the time)
4[ ]Most times (much more than half the time)
5[ ]Almost always/always
6. Over the past four weeks during sexual intercourse, how difficult was it to maintain your erection to completion of intercourse?
0[ ]Did not attempt intercourse
1[ ]Extremely difficult
2[ ]Very difficult
3[ ]Difficult
4[ ]Slightly difficult
5[ ]Not difficult
7. Over the past four weeks how many times have you attempted sexual intercourse?
0[ ]No attempts
1[ ]One or two attempts
2[ ]Three to four attempts
3[ ]Five to six attempts
4[ ]Seven to ten attempts
5[ ]Eleven+ attempts
8. Over the past four weeks when you attempted sexual intercourse, how often was it satisfactory for you?
0[ ]Did not attempt intercourse
1[ ]Almost never/never
2[ ]A few times (much less than half the time)
3[ ]Sometimes (about half the time)
4[ ]Most times (much more than half the time)
5[ ]Almost always/always
9. Over the past four weeks how much have you enjoyed sexual intercourse?
0[ ]No intercourse
1[ ]No enjoyment
2[ ]Not very enjoyable
3[ ]Fairly enjoyable
4[ ]Highly enjoyable
5[ ]Very highly enjoyable
10. Over the past four weeks when you had sexual stimulation or intercourse, how often did you ejaculate?
0[ ]No sexual stimulation/intercourse
1[ ]Almost never/never
2[ ]A few times (much less than half the time)
3[ ]Sometimes (about half the time)
4[ ]Most times (much more than half the time)
5[ ]Almost always/always
11. Over the past four weeks when you had sexual stimulation or intercourse, how often did you have the feeling of orgasm or climax?
0[ ]No sexual stimulation/intercourse
1[ ]Almost never/never
2[ ]A few times (much less than half the time)
3[ ]Sometimes (about half the time)
4[ ]Most times (much more than half the time)
5[ ]Almost always/always
12. Over the past four weeks how often have you felt sexual desire?
1[ ]Almost never/never
2[ ]A few times (much less than half the time)
3[ ]Sometimes (about half the time)
4[ ]Most times (much more than half the time)
5[ ]Almost always/always
13. Over the past four weeks how would you rate your level of sexual desire?
1[ ]Very low/none at all
2[ ]Low
3[ ]Moderate
4[ ]High
5[ ]Very high
14. Over the past four weeks how satisfied have you been with your overall sex life?
1[ ]Very dissatisfied
2[ ]Moderately dissatisfied
3[ ]About equally satisfied and dissatisfied
4[ ]Moderately satisfied
5[ ]Very satisfied
15. Over the past four weeks how satisfied have you been with your sexual relationship with your partner?
1[ ]Very dissatisfied
2[ ]Moderately dissatisfied
3[ ]About equally satisfied and dissatisfied
4[ ]Moderately satisfied
5[ ]Very satisfied
16. Over the past four weeks, how do you rate your confidence that you could get and keep an erection?
1[ ]Very low
2[ ]Low
3[ ]Moderate
4[ ]High
5[ ]Very high
Protocol Name from Source
Study for Future Families and International Index of Erectile Function (IIEF)
Availability
Personnel and Training Required
None
Equipment Needs
Pencil and paper
Requirements
| Requirement Category | Required |
|---|---|
| Major equipment | No |
| Specialized training | No |
| Specialized requirements for biospecimen collection | No |
| Average time of greater than 15 minutes in an unaffected individual | No |
Mode of Administration
Self-administered questionnaire
Life Stage
Adult
Participants
Adult males 18 years and older
Swan et al. (2003) sample included males 18-53 (question 1).
Rosen et al. (1997) sample included males 18 and older with a clinical diagnosis of erectile dysfunction (questions 2-16).
Selection Rationale
The Rosen questionnaire is the standard questionnaire currently used by researchers in the field of male sexual function. Question 1 adds additional important information.
Language
English
Standards
| Standard | Name | ID | Source |
|---|---|---|---|
| Common Data Elements (CDE) | Male Sexual Function | 3007476 | CDE Browser |
| Logical Observation Identifiers Names and Codes (LOINC) | Male sexual func proto | 62666-3 | LOINC |
| Human Phenotype Ontology | Male sexual dysfunction | HP:0040307 | HPO |
Derived Variables
None
Process and Review
The Expert Review Panel #5 (ERP 5) reviewed the measures in the Reproductive Health domain.
Guidance from ERP 5 includes:
- Revised descriptions of the measure
Back-compatible; no changes to Data Dictionary.
Previous version in Toolkit archive (link).
Source
Rosen, R. C., Riley, A., Wagner, G., Osterloh, I. H., Kirkpatrick, J., & Mishra, A. (1997). The International Index of Erectile Dysfunction (IIEF): A multidimensional scale for the assessment of erectile dysfunction. Urology, 49(6), 822-830. Questions 2-16.
Swan, S. H., Brazil, C., Drobnis, E. Z., Liu, F., Kruse, R. L., Hatch, M., . . . Overstreet, J. W.; Study for Future Families Group. (2003). Geographic differences in semen quality of fertile U.S. males. Environmental Health Perspectives, 111(4), 414-420. Question number 16 (question 1); utilizes question from Study for Future Families.
General References
Berner, M. M., Kriston, L., & Harms, A. (2006). Efficacy of PDE-5-inhibitors for erectile dysfunction. A comparative meta-analysis of fixed-dose regimen randomized controlled trials administering the International Index of Erectile Function in broad-spectrum populations. International Journal of Impotence Research, 18(3), 229-235.
Protocol ID
101001
Variables
Export Variables| Variable Name | Variable ID | Variable Description | dbGaP Mapping | |
|---|---|---|---|---|
| PX101001_Attempt_Sexual_Intercourse_Satisfactory | ||||
| PX101001080000 | Over the past four weeks when you attempted more | N/A | ||
| PX101001_Attempt_Sexual_Intercourse_Times | ||||
| PX101001070000 | Over the past four weeks how many times have more | N/A | ||
| PX101001_Confidence_Get_Keep_Erection | ||||
| PX101001160000 | Over the past four weeks how do you rate more | N/A | ||
| PX101001_Difficulty_Achieving_Erection | ||||
| PX101001010100 | How often did you have difficulty with more | N/A | ||
| PX101001_Difficulty_Ejaculating | ||||
| PX101001010300 | How often did you have difficulty with more | N/A | ||
| PX101001_Difficulty_Ejaculating_Early | ||||
| PX101001010200 | How often did you have difficulty with more | N/A | ||
| PX101001_Difficulty_Lack_Interest_Sex | ||||
| PX101001010400 | How often did you have difficulty with Lack more | N/A | ||
| PX101001_Enjoy_Sexual_Intercourse | ||||
| PX101001090000 | Over the past four weeks how much have you more | N/A | ||
| PX101001_Erection_During_Sexual_Activity | ||||
| PX101001020000 | Over the past four weeks how often were you more | N/A | ||
| PX101001_Erection_Hard_Enough_Penetration | ||||
| PX101001030000 | Over the past four weeks when you had more | N/A | ||
| PX101001_Maintain_Erection_After_Penetrated | ||||
| PX101001050000 | Over the past four weeks during sexual more | N/A | ||
| PX101001_Maintain_Erection_Completion_Intercourse | ||||
| PX101001060000 | Over the past four weeks during sexual more | N/A | ||
| PX101001_Overall_Sex_Life_Satisfied | ||||
| PX101001140000 | Over the past four weeks how satisfied have more | N/A | ||
| PX101001_Penetrate_Sexual_Intercourse | ||||
| PX101001040000 | Over the past four weeks when you attempted more | N/A | ||
| PX101001_Sexual_Desire_Felt | ||||
| PX101001120000 | Over the past four weeks how often have you more | N/A | ||
| PX101001_Sexual_Desire_Level_Rate | ||||
| PX101001130000 | Over the past four weeks how would you rate more | N/A | ||
| PX101001_Sexual_Stimulation_Intercourse_Ejaculate | ||||
| PX101001100000 | Over the past four weeks when you had sexual more | N/A | ||
| PX101001_Sexual_Stimulation_Intercourse_Orgasm_Climax | ||||
| PX101001110000 | Over the past four weeks when you had sexual more | N/A | ||
| PX101001_Sex_Relationship_Satisfied | ||||
| PX101001150000 | Over the past four weeks how satisfied have more | N/A | ||
Measure Name
Male Sexual Function
Release Date
February 26, 2010
Definition
Questions to determine whether a male participant has certain types of sexual function difficulties.
Purpose
The purpose of these questions is to determine whether the participant ever had sexual difficulties regarding erection and/or performance.
Keywords
Reproductive health, male sexual function, erectile dysfunction, International Index of Erectile Function, IIEF, Study for Future Families, SFF