Protocol - Male Sexual Function
Description
The participant answers whether he has had difficulty with erections and sexual function during the past 4 weeks.
Specific Instructions
Note: At the recommendation of the PhenX Reproductive Health Working Group, the response categories in questions 1A-1D have been reversed from the original questions.
Note: These questions reference the past 4 weeks.
Protocol
1. How often did you have difficulty with any of the following?
A. Achieving an erection
1[ ]Almost never
2[ ]Sometimes
3[ ]Often
4[ ]Almost always
B. Ejaculating too early
1[ ]Almost never
2[ ]Sometimes
3[ ]Often
4[ ]Almost always
C. Difficulty ejaculating
1[ ]Almost never
2[ ]Sometimes
3[ ]Often
4[ ]Almost always
D. Lack of interest in sex
1[ ]Almost never
2[ ]Sometimes
3[ ]Often
4[ ]Almost always
2. Over the past four weeks how often were you able to get an erection during sexual activity?
0[ ]No sexual activity
1[ ]Almost never/never
2[ ]A few times (much less than half the time)
3[ ]Sometimes (about half the time)
4[ ]Most times (much more than half the time)
5[ ]Almost always/always
3. Over the past four weeks when you had erections with sexual stimulation, how often were your erections hard enough for penetration?
0[ ]No sexual activity
1[ ]Almost never/never
2[ ]A few times (much less than half the time)
3[ ]Sometimes (about half the time)
4[ ]Most times (much more than half the time)
5[ ]Almost always/always
4. Over the past four weeks when you attempted sexual intercourse, how often were you able to penetrate (enter) your partner?
0[ ]Did not attempt intercourse
1[ ]Almost never/never
2[ ]A few times (much less than half the time)
3[ ]Sometimes (about half the time)
4[ ]Most times (much more than half the time)
5[ ]Almost always/always
5. Over the past four weeks during sexual intercourse, how often were you able to maintain your erection after you had penetrated (entered) your partner?
0[ ]Did not attempt intercourse
1[ ]Almost never/never
2[ ]A few times (much less than half the time)
3[ ]Sometimes (about half the time)
4[ ]Most times (much more than half the time)
5[ ]Almost always/always
6. Over the past four weeks during sexual intercourse, how difficult was it to maintain your erection to completion of intercourse?
0[ ]Did not attempt intercourse
1[ ]Extremely difficult
2[ ]Very difficult
3[ ]Difficult
4[ ]Slightly difficult
5[ ]Not difficult
7. Over the past four weeks how many times have you attempted sexual intercourse?
0[ ]No attempts
1[ ]One or two attempts
2[ ]Three to four attempts
3[ ]Five to six attempts
4[ ]Seven to ten attempts
5[ ]Eleven+ attempts
8. Over the past four weeks when you attempted sexual intercourse, how often was it satisfactory for you?
0[ ]Did not attempt intercourse
1[ ]Almost never/never
2[ ]A few times (much less than half the time)
3[ ]Sometimes (about half the time)
4[ ]Most times (much more than half the time)
5[ ]Almost always/always
9. Over the past four weeks how much have you enjoyed sexual intercourse?
0[ ]No intercourse
1[ ]No enjoyment
2[ ]Not very enjoyable
3[ ]Fairly enjoyable
4[ ]Highly enjoyable
5[ ]Very highly enjoyable
10. Over the past four weeks when you had sexual stimulation or intercourse, how often did you ejaculate?
0[ ]No sexual stimulation/intercourse
1[ ]Almost never/never
2[ ]A few times (much less than half the time)
3[ ]Sometimes (about half the time)
4[ ]Most times (much more than half the time)
5[ ]Almost always/always
11. Over the past four weeks when you had sexual stimulation or intercourse, how often did you have the feeling of orgasm or climax?
0[ ]No sexual stimulation/intercourse
1[ ]Almost never/never
2[ ]A few times (much less than half the time)
3[ ]Sometimes (about half the time)
4[ ]Most times (much more than half the time)
5[ ]Almost always/always
12. Over the past four weeks how often have you felt sexual desire?
1[ ]Almost never/never
2[ ]A few times (much less than half the time)
3[ ]Sometimes (about half the time)
4[ ]Most times (much more than half the time)
5[ ]Almost always/always
13. Over the past four weeks how would you rate your level of sexual desire?
1[ ]Very low/none at all
2[ ]Low
3[ ]Moderate
4[ ]High
5[ ]Very high
14. Over the past four weeks how satisfied have you been with your overall sex life?
1[ ]Very dissatisfied
2[ ]Moderately dissatisfied
3[ ]About equally satisfied and dissatisfied
4[ ]Moderately satisfied
5[ ]Very satisfied
15. Over the past four weeks how satisfied have you been with your sexual relationship with your partner?
1[ ]Very dissatisfied
2[ ]Moderately dissatisfied
3[ ]About equally satisfied and dissatisfied
4[ ]Moderately satisfied
5[ ]Very satisfied
16. Over the past four weeks, how do you rate your confidence that you could get and keep an erection?
1[ ]Very low
2[ ]Low
3[ ]Moderate
4[ ]High
5[ ]Very high
Availability
Personnel and Training Required
None
Equipment Needs
Pencil and paper
Requirements
| Requirement Category | Required |
|---|---|
| Major equipment | No |
| Specialized training | No |
| Specialized requirements for biospecimen collection | No |
| Average time of greater than 15 minutes in an unaffected individual | No |
Mode of Administration
Self-administered questionnaire
Life Stage
Adult
Participants
Adult males 18 years and older
Swan et al. (2003) sample included males 18-53 (question 1).
Rosen et al. (1997) sample included males 18 and older with a clinical diagnosis of erectile dysfunction (questions 2-16).
Selection Rationale
The Rosen questionnaire is the standard questionnaire currently used by researchers in the field of male sexual function. Question 1 adds additional important information.
Language
English
Standards
| Standard | Name | ID | Source |
|---|---|---|---|
| caDSR Common Data Elements (CDE) | Male Sexual Function | 3007476 | CDE Browser |
| Logical Observation Identifiers Names and Codes (LOINC) | Male sexual func proto | 62666-3 | LOINC |
| Human Phenotype Ontology | Male sexual dysfunction | HP:0040307 | HPO |
Derived Variables
None
Process and Review
The Expert Review Panel #5 (ERP 5) reviewed the measures in the Reproductive Health domain.
Guidance from ERP 5 includes:
- Revised descriptions of the measure
Back-compatible; no changes to Data Dictionary.
Previous version in Toolkit archive (link).
Protocol Name from Source
Study for Future Families and International Index of Erectile Function (IIEF)
Source
Rosen, R. C., Riley, A., Wagner, G., Osterloh, I. H., Kirkpatrick, J., & Mishra, A. (1997). The International Index of Erectile Dysfunction (IIEF): A multidimensional scale for the assessment of erectile dysfunction. Urology, 49(6), 822-830. Questions 2-16.
Swan, S. H., Brazil, C., Drobnis, E. Z., Liu, F., Kruse, R. L., Hatch, M., . . . Overstreet, J. W.; Study for Future Families Group. (2003). Geographic differences in semen quality of fertile U.S. males. Environmental Health Perspectives, 111(4), 414-420. Question number 16 (question 1); utilizes question from Study for Future Families.
General References
Berner, M. M., Kriston, L., & Harms, A. (2006). Efficacy of PDE-5-inhibitors for erectile dysfunction. A comparative meta-analysis of fixed-dose regimen randomized controlled trials administering the International Index of Erectile Function in broad-spectrum populations. International Journal of Impotence Research, 18(3), 229-235.
Protocol ID
101001
Variables
Export Variables| Variable Name | Variable ID | Variable Description | dbGaP Mapping | |
|---|---|---|---|---|
| PX101001_Attempt_Sexual_Intercourse_Satisfactory | ||||
| PX101001080000 | Over the past four weeks when you attempted more | N/A | ||
| PX101001_Attempt_Sexual_Intercourse_Times | ||||
| PX101001070000 | Over the past four weeks how many times have more | N/A | ||
| PX101001_Confidence_Get_Keep_Erection | ||||
| PX101001160000 | Over the past four weeks how do you rate more | N/A | ||
| PX101001_Difficulty_Achieving_Erection | ||||
| PX101001010100 | How often did you have difficulty with more | N/A | ||
| PX101001_Difficulty_Ejaculating | ||||
| PX101001010300 | How often did you have difficulty with more | N/A | ||
| PX101001_Difficulty_Ejaculating_Early | ||||
| PX101001010200 | How often did you have difficulty with more | N/A | ||
| PX101001_Difficulty_Lack_Interest_Sex | ||||
| PX101001010400 | How often did you have difficulty with Lack more | N/A | ||
| PX101001_Enjoy_Sexual_Intercourse | ||||
| PX101001090000 | Over the past four weeks how much have you more | N/A | ||
| PX101001_Erection_During_Sexual_Activity | ||||
| PX101001020000 | Over the past four weeks how often were you more | N/A | ||
| PX101001_Erection_Hard_Enough_Penetration | ||||
| PX101001030000 | Over the past four weeks when you had more | N/A | ||
| PX101001_Maintain_Erection_After_Penetrated | ||||
| PX101001050000 | Over the past four weeks during sexual more | N/A | ||
| PX101001_Maintain_Erection_Completion_Intercourse | ||||
| PX101001060000 | Over the past four weeks during sexual more | N/A | ||
| PX101001_Overall_Sex_Life_Satisfied | ||||
| PX101001140000 | Over the past four weeks how satisfied have more | N/A | ||
| PX101001_Penetrate_Sexual_Intercourse | ||||
| PX101001040000 | Over the past four weeks when you attempted more | N/A | ||
| PX101001_Sexual_Desire_Felt | ||||
| PX101001120000 | Over the past four weeks how often have you more | N/A | ||
| PX101001_Sexual_Desire_Level_Rate | ||||
| PX101001130000 | Over the past four weeks how would you rate more | N/A | ||
| PX101001_Sexual_Stimulation_Intercourse_Ejaculate | ||||
| PX101001100000 | Over the past four weeks when you had sexual more | N/A | ||
| PX101001_Sexual_Stimulation_Intercourse_Orgasm_Climax | ||||
| PX101001110000 | Over the past four weeks when you had sexual more | N/A | ||
| PX101001_Sex_Relationship_Satisfied | ||||
| PX101001150000 | Over the past four weeks how satisfied have more | N/A | ||
Measure Name
Male Sexual Function
Release Date
February 26, 2010
Definition
Questions to determine whether a male participant has certain types of sexual function difficulties.
Purpose
The purpose of these questions is to determine whether the participant ever had sexual difficulties regarding erection and/or performance.
Keywords
Reproductive health, male sexual function, erectile dysfunction, International Index of Erectile Function, IIEF, Study for Future Families, SFF