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Research Domain - Reproductive Health

Assessment of Pubertal Development - Female

Avon Longitudinal Study of Parents and Children (ALSPAC). Growing and Changing (8), Female Teenage Questionnaire

Assessment of Pubertal Development - Male

Avon Longitudinal Study of Parents and Children (ALSPAC). Growing and Changing (8), Male Teenager Questionnaire

Causes and Treatments of Known Infertility - Female

National Survey of Family Growth (NSFG)

Causes and Treatments of Known Infertility - Male

National Survey of Family Growth (NSFG)

Current Contraception Use - Female

National Survey of Family Growth

Current Contraception Use - Male

National Survey of Family Growth (NSFG)

Difficulty Getting Pregnant - Current Duration
Difficulty Getting Pregnant - Prospective Assessment

Pregnancy Study Online (PRESTO) Female Screener and Baseline Questionnaire

Difficulty Getting Pregnant - Retrospective Assessment
History of Prepubertal Development - Female

Black Women’s Health Study (BWHS)

History of Prepubertal Development - Male

Study for Future Families (SFF) and National Longitudinal Survey of Youth (NLSY)

Hormonal Therapy

Nurses’ Health Study II (NHS II)

Human Papillomavirus Vaccine Use

Behavioral Risk Factor Surveillance System (BRFSS)

Male Fertility Status

WHO Laboratory Manual for the Examination and Processing of Human Semen, Fifth Edition

Male Reproductive Tract Birth Defects

Study For Future Families

Male Sexual Function

Study for Future Families and International Index of Erectile Function (IIEF)

Menstrual History

Nurses’ Health Study (NHS), Black Women’s Health Study (BWHS), Study of Women Across the Nation (SWAN)

Prostate Symptoms

International Prostate Symptom Score (I-PSS)

Removal of Female Reproductive Organs

National Survey of Family Growth (NSFG)

Reproductive History - Female

Women’s Interview Study of Health and Pregnancy Risk Assessment Monitoring System (PRAMS)

Reproductive History - Male

The Longitudinal Investigation of Fertility and the Environment (LIFE) Study

Sexual Risk Behavior - Female

National Health and Nutrition Examination Survey (NHANES) Sexual Behavior Module

Sexual Risk Behavior - Male

National Health and Nutrition Examination Survey (NHANES) Sexual Behavior Module

Testes Volume

Assessment of Sexual Maturity Stages in Girls and Boys and Williams Textbook of Endocrinology

Release Date:

February 26, 2010; reviewed April 11, 2017

Scope of Domain:
Scope Elements Final Measures To Toolkit
Maturation Assessment of Pubertal Development
Infertility, known infertility, cause of known infertility, any use of infertility treatment Causes and Treatments of Known Infertility
Contraceptive use (including hormonal contraception), voluntary sterilization, condom or other male-oriented contraceptive use Contraceptive Methods
Infertile periods (periods of unprotected sex without pregnancy) Difficulty in Conceiving
Surgical procedures (e.g., oophorectomy, hysterectomy) Female Reproductive Organ Surgical Procedures
Hormone replacement therapy Hormonal Therapy
HPV vaccinations, e.g., Gardasil Human Papillomavirus Use
Age at menarche; age at puberty; maturation, first-time masturbation/ejaculation, prepubertal questions History of Prepubertal Development
Hypogonadal, hypospadias, cryptorchidism, prepuberty Male Reproductive Tract Birth Defects
Age at menopause; extended periods of amenorrhea Menstrual History
Prostate diseases and symptoms Prostate Health
Number of pregnancies and spacing; outcome of each pregnancy; maternal complications (pregnancy-related death or morbidity); infant health parameters (preterm, low birth weight, congenital anomalies, gestational age); alcohol use; number of pregnancies fathered Reproductive History
Sexual difficulties Sexual Function, Male
Age at first intercourse; number of sexual partners Sexual History
Maturation through clinical exam Testes Development
Current sexual activity Current Sexual Activity (supplemental)
Rape and other sexual abuse Forced Sexual Activity (supplemental)
Working Group Roster:

WG Members:

Carol Hogue, PhD, Chair
Emory University
Atlanta, GA
Stephanie Seminara, MD
Massachusetts General Hospital
Boston, MA
Andrea Dunaif, MD
Northwestern University
Evanston, IL
Rebecca Sokol, MD
University of Southern California
Los Angeles, CA
Russ Hauser, MD, ScD
Harvard University
Belmont, MA
Jun (Jim) Zhang, MD, PhD
Eunice Kennedy Shriver National Institute
of Child Health and Human Development (NICHD)
Rockville, MD
Pauline Mendola, PhD
Centers for Disease Control and Prevention
Prevention/National Center for Health Statistics
Hyattsville, MD

SC Liaison, WG Manager and WG Supervisor:

Michelle A. Williams, ScD, SC Liaison
Harvard University
School of Public Health
Belmont, MA
Sonja Hoover, MPP, WG Manager
RTI International
Waltham, MA
Richard Kwok, PhD, WG Supervisor
RTI International
Research Triangle Park, NC
Expert Review Panel 5 - Reproductive Health domain:

ERP Members:

John Amory, MD
University of Washington, Seattle
Seattle, WA
Courtney Lynch, PhD
The Ohio State University
Columbus, OH

SC Liaison, ERP Manager and ERP Supervisor:

Elaine M. Faustman, PhD, SC Liaison
University of Washington, Seattle
Seattle, WA
Lisa Kilpatrick, MS, ERP Manager
RTI International
Atlanta, GA
Michael Phillips, MS, ERP Supervisor
RTI International
Research Triangle Park, NC
Reproductive Health Supplemental Information includes:
  • Sexual Violence
  • Additional Information for Reproductive Health Measures:

    There is no additional information for this domain.