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Research Domain - Reproductive Health

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Avon Longitudinal Study of Parents and Children (ALSPAC), Growing and Changing (8), Female Teenage Questionnaire
#100101

Avon Longitudinal Study of Parents and Children (ALSPAC), Growing and Changing (8), Male Teenage Questionnaire
#100102

National Survey of Family Growth (NFSG), 2013-2015
#100204

National Survey of Family Growth (NFSG), Male, 2013-2015
#100203

National Survey of Family Growth (NFSG), 2013-2015
#100303

National Survey of Family Growth (NFSG), Male, 2013-2015
#100304

Slama, R., et al, Feasibility of the Current-Duration Approach to Studying Human Fecundity, EPIDEMIOLOGY, 2006
#100402

Pregnancy Study Online (PRESTO), Female Screener and Baseline Questionnaire
#100403

Slama, R., et al, Epidemiologic tools to study the influence of environmental factors on fecundity and pregnancy-related outcomes, EPIDEMIOL REVs, 2014
#100404

Black Women’s Health Study (BWHS), 1995
#100601

Study for Future Families (SFF) & National Longitudinal Survey of Youth (NLSY)
#100602

Nurses’ Health Study II (NHS II), 2015
#100702

Behavioral Risk Factor Surveillance System (BRFSS), 2014
#100802

WHO Laboratory Manual for the Examination and Processing of Human Semen, Fifth Edition, 2010
#101601

Study For Future Families
#100901

Study for Future Families & International Index of Erectile Function (IIEF)
#101001

Nurses’ Health Study (NHS), Black Women’s Health Study (BWHS), Study of Women Across the Nation (SWAN)
#101101

International Prostate Symptom Score (I-PSS)
#101202

National Survey of Family Growth (NSFG), 2011-2013
#100502

Women’s Interview Study of Health & Pregnancy Risk Assessment Monitoring System (PRAMS), 2009
#101301

The Longitudinal Investigation of Fertility & the Environment (LIFE) Study, 2005
#101302

National Health and Nutrition Examination Survey (NHANES), Sexual Behavior Module, 2011-2012
#101702

National Health and Nutrition Examination Survey (NHANES), Sexual Behavior Module, 2011-2012
#101701

Melmed, S., et al. Williams textbook of endocrinology, 2008
#101501
Release Date:

February 26, 2010; reviewed April 11, 2017

Scope of Domain:
Scope Elements Final Protocols To Toolkit (17)
Maturation Assessment of Pubertal Development
Infertility, known infertility, cause of known infertility, any use of infertility treatment Causes and Treatments of Known Infertility
Contraceptive use (including hormonal contraception), voluntary sterilization, condom or other male-oriented contraceptive use Contraceptive Methods
Infertile periods (periods of unprotected sex without pregnancy) Difficulty in Conceiving
Surgical procedures (e.g., oophorectomy, hysterectomy) Female Reproductive Organ Surgical Procedures
Hormone replacement therapy Hormonal Therapy
HPV vaccinations, e.g., Gardasil Human Papillomavirus Use
Age at menarche; age at puberty; maturation, first-time masturbation/ejaculation, prepubertal questions History of Prepubertal Development
Hypogonadal, hypospadias, cryptorchidism, prepuberty Male Reproductive Tract Birth Defects
Age at menopause; extended periods of amenorrhea Menstrual History
Prostate diseases and symptoms Prostate Health
Number of pregnancies and spacing; outcome of each pregnancy; maternal complications (pregnancy-related death or morbidity); infant health parameters (preterm, low birth weight, congenital anomalies, gestational age); alcohol use; number of pregnancies fathered Reproductive History
Sexual difficulties Sexual Function, Male
Age at first intercourse; number of sexual partners Sexual History
Maturation through clinical exam Testes Development
Current sexual activity Current Sexual Activity (supplemental)
Rape and other sexual abuse Forced Sexual Activity (supplemental)
Working Group Roster:

WG Members:

Carol Hogue, PhD, Chair
Emory University
Atlanta, GA
Stephanie Seminara, MD
Massachusetts General Hospital
Boston, MA
Andrea Dunaif, MD
Northwestern University
Evanston, IL
Rebecca Sokol, MD
University of Southern California
Los Angeles, CA
Russ Hauser, MD, ScD
Harvard University
Belmont, MA
Jun (Jim) Zhang, MD, PhD
Eunice Kennedy Shriver National Institute of Child Health and
Human Development (NICHD)
Rockville, MD
Pauline Mendola, PhD
Centers for Disease Control and Prevention
Prevention/National Center for Health Statistics
Hyattsville, MD

SC Liaison, WG Manager and WG Supervisor:

Michelle A. Williams, ScD, SC Liaison
Harvard University
School of Public Health
Belmont, MA
Sonja Hoover, MPP, WG Manager
RTI International
Waltham, MA
Richard Kwok, PhD, WG Supervisor
RTI International
Research Triangle Park, NC
Expert Review Panel 5 - Reproductive Health domain:

ERP Members:

John Amory, MD
University of Washington
Seattle, WA
Courtney Lynch, PhD
The Ohio State University
Columbus, OH

SC Liaison, ERP Manager and ERP Supervisor:

Elaine M. Faustman, PhD, SC Liaison
University of Washington
Seattle, WA
Lisa Cox, MS, ERP Manager
RTI International
Atlanta, GA
Michael Phillips, MS, ERP Supervisor
RTI International
Research Triangle Park, NC
Reproductive Health Supplemental Information includes:
Additional Information for Reproductive Health Measures:

There is no additional information for this domain.

Select Measure Name Protocols
Assessment of Pubertal Development Assessment of Pubertal Development - Female
Assessment of Pubertal Development - Male
Causes and Treatments of Known Infertility Causes and Treatments of Known Infertility - Male
Causes and Treatments of Known Infertility - Female
Causes and Treatments of Known Infertility - Male
Causes and Treatments of Known Infertility - Female
Current Contraception Use Contraceptive Methods - Female
Contraceptive Methods - Male
Current Contraception Use - Female
Current Contraception Use - Male
Difficulty Getting Pregnant Difficulty in Conceiving
Difficulty Getting Pregnant - Current Duration
Difficulty Getting Pregnant - Prospective Assessment
Difficulty Getting Pregnant - Retrospective Assessment
Removal of Female Reproductive Organs Female Reproductive Organ Surgical Procedures
Removal of Female Reproductive Organs
History of Prepubertal Development History of Prepubertal Development - Female
History of Prepubertal Development - Male
Hormonal Therapy Hormonal Therapy
Hormonal Therapy
Human Papillomavirus Vaccine Use Human Papillomavirus Vaccine Use
Human Papillomavirus Vaccine Use
Male Reproductive Tract Birth Defects Male Reproductive Tract Birth Defects
Male Sexual Function Male Sexual Function
Menstrual History Menstrual History
Prostate Symptoms Prostate Health
Prostate Symptoms
Reproductive History Reproductive History - Female
Reproductive History - Male
Sexual History Sexual History
Testes Volume Testes Volume
Male Fertility Status Male Fertility Status
Sexual Risk Behavior Sexual Risk Behavior - Male
Sexual Risk Behavior - Female