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Research Domain - Reproductive Health

Assessment of Pubertal Development - Female

Avon Longitudinal Study of Parents and Children (ALSPAC). Growing and Changing (8), Female Teenage Questionnaire

#100101
Assessment of Pubertal Development - Male

Avon Longitudinal Study of Parents and Children (ALSPAC). Growing and Changing (8), Male Teenager Questionnaire

#100102
Causes and Treatments of Known Infertility - Female

National Survey of Family Growth (NSFG)

#100204
Causes and Treatments of Known Infertility - Male

National Survey of Family Growth (NSFG)

#100203
Current Contraception Use - Female

National Survey of Family Growth

#100303
Current Contraception Use - Male

National Survey of Family Growth (NSFG)

#100304
Difficulty Getting Pregnant - Current Duration
#100402
Difficulty Getting Pregnant - Prospective Assessment

Pregnancy Study Online (PRESTO) Female Screener and Baseline Questionnaire

#100403
Difficulty Getting Pregnant - Retrospective Assessment
#100404
History of Prepubertal Development - Female

Black Women’s Health Study (BWHS)

#100601
History of Prepubertal Development - Male

Study for Future Families (SFF) and National Longitudinal Survey of Youth (NLSY)

#100602
Hormonal Therapy

Nurses’ Health Study II (NHS II)

#100702
Human Papillomavirus Vaccine Use

Behavioral Risk Factor Surveillance System (BRFSS)

#100802
Male Fertility Status

WHO Laboratory Manual for the Examination and Processing of Human Semen, Fifth Edition

#101601
Male Reproductive Tract Birth Defects

Study For Future Families

#100901
Male Sexual Function

Study for Future Families and International Index of Erectile Function (IIEF)

#101001
Menstrual History

Nurses’ Health Study (NHS), Black Women’s Health Study (BWHS), Study of Women Across the Nation (SWAN)

#101101
Prostate Symptoms

International Prostate Symptom Score (I-PSS)

#101202
Removal of Female Reproductive Organs

National Survey of Family Growth (NSFG)

#100502
Reproductive History - Female

Women’s Interview Study of Health and Pregnancy Risk Assessment Monitoring System (PRAMS)

#101301
Reproductive History - Male

The Longitudinal Investigation of Fertility and the Environment (LIFE) Study

#101302
Sexual Risk Behavior - Female

National Health and Nutrition Examination Survey (NHANES) Sexual Behavior Module

#101702
Sexual Risk Behavior - Male

National Health and Nutrition Examination Survey (NHANES) Sexual Behavior Module

#101701
Testes Volume

Assessment of Sexual Maturity Stages in Girls and Boys and Williams Textbook of Endocrinology

#101501
Release Date:

February 26, 2010; reviewed April 11, 2017

Scope of Domain:
Scope Elements Final Measures To Toolkit
Maturation Assessment of Pubertal Development
Infertility, known infertility, cause of known infertility, any use of infertility treatment Causes and Treatments of Known Infertility
Contraceptive use (including hormonal contraception), voluntary sterilization, condom or other male-oriented contraceptive use Contraceptive Methods
Infertile periods (periods of unprotected sex without pregnancy) Difficulty in Conceiving
Surgical procedures (e.g., oophorectomy, hysterectomy) Female Reproductive Organ Surgical Procedures
Hormone replacement therapy Hormonal Therapy
HPV vaccinations, e.g., Gardasil Human Papillomavirus Use
Age at menarche; age at puberty; maturation, first-time masturbation/ejaculation, prepubertal questions History of Prepubertal Development
Hypogonadal, hypospadias, cryptorchidism, prepuberty Male Reproductive Tract Birth Defects
Age at menopause; extended periods of amenorrhea Menstrual History
Prostate diseases and symptoms Prostate Health
Number of pregnancies and spacing; outcome of each pregnancy; maternal complications (pregnancy-related death or morbidity); infant health parameters (preterm, low birth weight, congenital anomalies, gestational age); alcohol use; number of pregnancies fathered Reproductive History
Sexual difficulties Sexual Function, Male
Age at first intercourse; number of sexual partners Sexual History
Maturation through clinical exam Testes Development
Current sexual activity Current Sexual Activity (supplemental)
Rape and other sexual abuse Forced Sexual Activity (supplemental)
Working Group Roster:

WG Members:

Carol Hogue, PhD, Chair
Emory University
Atlanta, GA
Stephanie Seminara, MD
Massachusetts General Hospital
Boston, MA
Andrea Dunaif, MD
Northwestern University
Evanston, IL
Rebecca Sokol, MD
University of Southern California
Los Angeles, CA
Russ Hauser, MD, ScD
Harvard University
Belmont, MA
Jun (Jim) Zhang, MD, PhD
Eunice Kennedy Shriver National Institute
of Child Health and Human Development (NICHD)
Rockville, MD
Pauline Mendola, PhD
Centers for Disease Control and Prevention
Prevention/National Center for Health Statistics
Hyattsville, MD

SC Liaison, WG Manager and WG Supervisor:

Michelle A. Williams, ScD, SC Liaison
Harvard University
School of Public Health
Belmont, MA
Sonja Hoover, MPP, WG Manager
RTI International
Waltham, MA
Richard Kwok, PhD, WG Supervisor
RTI International
Research Triangle Park, NC
Expert Review Panel 5 - Reproductive Health domain:

ERP Members:

John Amory, MD
University of Washington, Seattle
Seattle, WA
Courtney Lynch, PhD
The Ohio State University
Columbus, OH

SC Liaison, ERP Manager and ERP Supervisor:

Elaine M. Faustman, PhD, SC Liaison
University of Washington, Seattle
Seattle, WA
Lisa Kilpatrick, MS, ERP Manager
RTI International
Atlanta, GA
Michael Phillips, MS, ERP Supervisor
RTI International
Research Triangle Park, NC
Reproductive Health Supplemental Information includes:
  • Sexual Violence
  • Additional Information for Reproductive Health Measures:

    There is no additional information for this domain.