Protocol - Eye Drop Use
A series of five questions to assess the participants current use of drops for glaucoma, artificial tears or prescription medication for dry eyes, and steroid eye drops.
Question 3: There are many manifestations of "dry eye" besides the symptoms in the question, including excess tearing. Most people will be familiar with this condition. They need not have been told by an eye doctor they have this condition. Emphasize "for the past 3 months or longer" when you ask this question. If the participant has occasional episodes of dry eye, it should on average be a complaint at least 4 out of 7 days for the past 3 months or longer. Emphasize "not related to allergy" when using the probe for this question.
Question 4: There are a number of over-the-counter artificial tears which are used for this condition. Visine, taken for allergies, does not qualify as an artificial tear unless specifically prescribed for dry eye. Drops taken for contact lens do not qualify as artificial tears for dry eye. Note that the question requires current (4 out of 7 days) use for 3 months or longer.
1. Is the participant currently taking drops for glaucoma?
2. What is the name of the glaucoma drops you are using?
[ ] Other _________________
3. For the past 3 months or longer, have you had dry eyes? (foreign body sensation with itching and burning, sandy feeling, NOT related to allergy)
4. Do you currently use artificial tears or prescription medication for dry eyes regularly for 3 months or longer?
5. Are you currently using steroid eye drops?
Alphagan® and Betagen® are a registered trademarks of Allergan, Inc,; CoSopt® and Timoptic® are registered trademarks of Merck & Co., Inc.; Pilocar® is a registered trademark of Novartis Corporation; Xalatan® is a registered trademark of Pfizer Health AB.
Personnel and Training Required
The interviewer must be trained to conduct personal interviews with individuals from the general population. The interviewer must be trained and found to be competent (i.e. tested by an expert) at the completion of personal interviews*.
*There are multiple modes to administer this question (i.e., pencil and paper and computer-assisted interviews).
Either a pencil and paper or computer-assisted instrument may be used. If a computer-assisted instrument is used, computer software may be necessary to develop the instrument. The interviewer will require a laptop computer/handheld computer to administer a computer-assisted questionnaire.
|Specialized requirements for biospecimen collection||No|
|Average time of greater than 15 minutes in an unaffected individual||No|
Mode of Administration
Adults aged 43 to 86 years*
* While this protocol was used in a study of adults aged 43 to 86 years, the Ocular Working Group suggests that the same methodology can be used for individuals aged 18 years or older.
The questions suggested have had wide use in long term studies of ocular diseases.
|caDSR Common Data Elements (CDE)||Person Eye Drops Use Assessment||3007567||CDE Browser|
|Logical Observation Identifiers Names and Codes (LOINC)||Eye drop use proto||62687-9||LOINC|
Process and Review
Protocol Name from Source
SourceNational Eye Institute, University of Wisconsin, Beaver Dam Eye Study
Beaver Dam V- 20 Year Follow-Up Interview Form
Question numbers: 55-570 [GLAU-DROPS5] (question 1), 55-572 [GLAU-NAME5] (question 2), 56-092 [DRY-EYE5] (question 3), 56-094 [DRY-EYE-RX5] (question 4), and 56-114 [STEROIDROP5] (question 5).
Last revised 2/6/09
Wong TY, Knudtson MD, Klein BE, Klein R, Hubbard LD. (2005). Medication use and retinal vessel diameters. Am J Ophthalmol, 139(2):373-5.
|Variable Name||Variable ID||Variable Description||dbGaP Mapping|
|PX110501010000||Is the participant currently taking drops more||Variable Mapping|
|PX110501050000||Are you currently using steroid eye drops?||Variable Mapping|
|PX110501030000||For the past 3 months or longer, have you more||Variable Mapping|
|PX110501040000||Do you currently use artificial tears or more||Variable Mapping|
|PX110501020100||What is the name of the glaucoma drops you more||N/A|
|PX110501020200||Specify other glaucoma drops you are using.||N/A|
Eye Drop Use
February 26, 2010
Questions to determine current and recent eye drop use
These questions are to assess use of eye drops in general for those investigators who are interested in use of both prescription and over the counter medications. Use of specific medications may be used to augment information about the burden of specific eye conditions such as glaucoma. Also, some of the medications have systemic effects which may be of interest to an investigator.
Ocular, Eye, Eye drops, Artificial tears, Medications, Beaver Dam Eye Study