Protocol - Sexual Orientation

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A multi-part question asking participants to describe their sexual orientation. Multiple response options are provided along with an open-ended option.

Specific Instructions

While the original protocol is intended for computer administration, the PhenX Steering Committee acknowledges these items would be acceptable for use in paper-pencil questionnaires.


1a. Which of the following best represents how you think of yourself?

[ ] Gay

[ ] Lesbian

[ ] Straight; that is, not gay or lesbian, etc.

[ ] Bisexual

[ ] None of these describe me, and I’d like to see additional options

Branching logic: If ‘none of these describe me, and I’d like to see additional options’ selected:

1b. Are any of these a closer description of how you think of yourself? 

[ ] Queer

[ ] Polysexual, omnisexual, sapiosexual or pansexual

[ ] Asexual

[ ] Two-spirit

[ ] Have not figured out or are in the process of figuring out your sexuality

[ ] Mostly straight, but sometimes attracted to people of your own sex

[ ] Do not think of yourself as having sexuality

[ ] Do not use labels to identity yourself

[ ] Don’t know the answer

[ ] No, I mean something else (optional free text) __________________

[ ] Prefer not to answer



Personnel and Training Required


Equipment Needs

The PhenX Steering Committee acknowledges these questions can be administered in a computerized or noncomputerized format (i.e., paper-and-pencil instrument). Computer software is necessary to develop computer-assisted instruments. The interviewer will require a laptop computer/handheld computer to administer a computer-assisted questionnaire."

Requirement CategoryRequired
Major equipment No
Specialized training No
Specialized requirements for biospecimen collection No
Average time of greater than 15 minutes in an unaffected individual No
Mode of Administration

Self-administered or interviewer-administered questionnaire


Adult, Senior


Adults aged 18 and older

Selection Rationale

This protocol was selected because it is both the most up-to-date and in use by the national All of Us research program.


English, Other languages available at source

caDSR Common Data Elements (CDE) Person Biological Entity Sexual Orientation Code PCORnet CDM Sexual Orientation Code 6421669 CDE Browser
Derived Variables


Process and Review

Not applicable.

Protocol Name from Source

All of Us Research Program, Participant Provided Information (PPI), 2018


All of Us Research Program Participant Provided Information (PPI) Version: December 17, 2018

General References

The Precision Medicine Initiative Cohort Program – Building a Research Foundation for 21st Century Medicine Precision Medicine Initiative (PMI) Working Group Report to the Advisory Committee to the Director, NIH September 17, 2015

Collins, F. S. and Varmus, H. (2015). A New Initiative on Precision Medicine. N Engl J Med, 372, 793-795

National Research Council. Toward precision medicine: building a knowledge network for biomedical research and a new taxonomy of disease. Washington, DC: National Academies Press, 2011 (http://www.nap.edu/catalog/13284/toward-precision-medicine-building-a-knowledge-network-for-biomedical-research).

Perron, T., Kartoz, C., Himelfarb, C., LGBTQ Youth Part 1. National Association of School Nurses, 2017 Mar. 32(2): 106-115.

Perron, T., Kartoz, C., Himelfarb, C. LGBTQ Part 2. National Association of School Nurses. 2017 Mar. 32(2): 116-121.

The GenIUSS Group. (2014). Best Practices for Asking Questions to Identify Transgender and Other Gender Minority Respondents on Population-Based Surveys. J.L. Herman (Ed.). Los Angeles, CA: The Williams Institute.

Protocol ID


Export Variables
Variable Name Variable IDVariable DescriptiondbGaP Mapping
PX011701020100 Are any of these a closer description of how more
you think of yourself? show less
PX011701020200 Are any of these a closer description of how more
you think of yourself? Other show less
PX011701010000 Which of the following best represents how more
you think of yourself? show less
Measure Name

Sexual orientation

Release Date

June 4, 2019


An emotional, romantic, or sexual attraction to other people.


To obtain a self-report of a person’s romantic attraction to other people, be it gay, lesbian, straight, bisexual, or something else.


sexual orientation, sex, gender, LGBTQ, LGBTQIA, Gay, Lesbian, Bisexual, Intersex, Asexual, Queer, transgender, Questioning, Demographics-Populations with HD

Measure Protocols
Protocol ID Protocol Name
11701 Sexual Orientation

There are no publications listed for this protocol.