Protocol - Tobacco - Age of Initiation of Use - Adolescent
Measurement to ascertain the respondent’s age of initiation of first/regular use of cigarettes, which can be used to calculate duration of use and pack-years measures.
All adolescent respondents are asked if they smoked in the last 30 days. If the respondent has smoked during the past 30 days, he or she is asked to report the quantity and frequency of cigarette smoking.
The respondent is classified as an Every-Day Smoker, Some-Day Smoker, or Former Smoker based on how they respond to the second question in the Tobacco - Smoking Status protocol: Do you now smoke cigarettes every day, some days, or not at all?
The Working Group acknowledges that the following questions may gather sensitive information relating to the use of substances and/or illegal conduct. If the information is released it might be damaging to an individuals employability, lead to social stigmatization, or other consequences.
For information on obtaining a Certificate of Confidentiality, which helps researchers protect the privacy of human research participants, please go to the National Human Genome Research Institutes Institutional Review Board website.
Note to interviewer: Respondents who were classified as a "Smoker" or "Non Smoker" in the Tobacco - Smoking Status (Adolescent Protocol) (by answering Question 1 as "Yes" [Have you ever smoked part or all of a cigarette?]) are asked the following question:
How old were you the first time you smoked part or all of a cigarette?
AGE: ____ [RANGE: 1 - 110]
Dont Know / Refused
Note to interviewer: Respondents who were classified as a Current Every-Day Smoker in the Tobacco - Smoking Status (Adolescent Protocol) as well as respondents who were classified as a Current Some-Day Smoker or a Former Smoker and also answered the Tobacco - Lifetime Use (Adolescent Protocol), Question 3 as "Yes" (Has there ever been a period in your life when you smoked cigarettes every day for at least 30 days?) are asked:
How old were you when you first started smoking cigarettes every day?
AGE: ____ [RANGE: 1 - 110]
Dont Know / Refused
Personnel and Training Required
If an interviewer prepares the survey for self-administration, the interviewer must be trained and found competent to conduct personal interviews with individuals from the general population.
While the source instrument was developed for administration by computer, the PhenX Working Group acknowledges that these questions can be administered in a noncomputerized format.
|Specialized requirements for biospecimen collection||No|
|Average time of greater than 15 minutes in an unaffected individual||No|
Mode of Administration
12 through 17 years of age*
* If the study population consists of adolescents and young adults (12-24 years) with the intention of studying onset of risky behaviors, the investigator may wish to use the adolescent profile. If the study population primarily consists of adults (≥18 years), emphasizing established smoking and/or cessation, the investigator should use the adult profile.
The protocol from the National Survey on Drug Use and Health (NSDUH) was selected because this survey is the primary combined source of information on the use of drugs, alcohol, and tobacco in the civilian, noninstitutionalized population of the United States. The study was initiated in 1971, and it is currently conducted on an annual basis. The NSDUH is a survey that includes all substance use and that is administered to individuals ages 12 years and older. This survey asks many additional questions that may be more relevant to investigators studying adolescent subjects.
|caDSR Common Data Elements (CDE)||Tobacco Adolescent Begin Age||2923476||CDE Browser|
|Logical Observation Identifiers Names and Codes (LOINC)||Tobac age init use adoles proto||62556-6||LOINC|
Duration of smoking: (Tobacco - Age of Offset of Cigarette Use1 OR Current Age) - (Tobacco - Age of Initiation of First Cigarette Use)2
Pack-years: (Tobacco - 30-Day Quantity and Frequency)3 X (Duration)4
1 Tobacco - Age of Offset of Cigarette Use:
- Adolescents: (Current Age) - (length of time response to the question: "How old were you the last time you smoked part or all of a cigarette?")
- Adults: (Current Age) - (length of time response to the question: "About how long has it been since you COMPLETELY quit smoking cigarettes?")
2 Tobacco - Age of Initiation of First Cigarette Use:
- Adolescents: Age derived from the answer to: 2. "How old were you when you first started smoking cigarettes every day?" OR - For those who never smoked every day, the answer from 1. "How old were you when you first smoked part or all of a cigarette?"
- Adults: Age derived from the answer to: 1. "How old were you when you first started smoking cigarettes every day?" OR - For those who never smoked every day, the answer from 2. "How old were you when you first started smoking cigarettes fairly regularly?"
3 Tobacco - 30-Day Quantity and Frequency:
- Adolescents: Response to question "On the [number of days reported in 2a or 2b] you smoked cigarettes during the past 30 days, how many cigarettes did you smoke per day, on average?"
- Every-day smokers: Response to question "On the average, about how many cigarettes do you now smoke each day?"
- Some-day smokers: [(Response to question "On the average, on those days, how many cigarettes did you usually smoke each day?") X (Response to "On how many of the past 30 days did you smoke cigarettes?")] / 30
- Former smokers:
- Respondents who smoked every day for ≥6 months: Response to question "When you last smoked every day, on average how many cigarettes did you smoke each day?"
- Respondents who did not smoke every day for ≥6 months: Response to question "When you last smoked fairly regularly, on average how many cigarettes did you smoke each day?"
- The Fagerstrom Test for Nicotine Dependence measure (4. How many cigarettes/day do you smoke?) can also be used to calculate the amount of cigarettes smoked.
- Use the midpoint from the response category to obtain the number of cigarettes smoked per day.
4 Duration calculation provided above
Process and Review
The Expert Review Panel #3 (ERP 3) reviewed the measures in Alcohol, Tobacco and Other Substances, and Substance Abuse and Addiction domains.
Guidance from ERP 3 includes:
· Changed name of measure
Back-compatible: NA no changes to Data Dictionary
Previous version in Toolkit archive (link)
Protocol Name from Source
National Survey on Drug Use and Health (NSDUH), 2008
2008 National Survey on Drug Use and Health. CAI Specifications for Programming, English Version; November 2007 (questions CG04, CG16).
Amos, C. I., Wu, X., Broderick, P., Gorlov, I. P., Gu, J., Eisen, T., Dong, Q., Zhang, Q., Gu, X., Vijayakrishnan, J., Sullivan, K., Matakidou, A., Wang, Y., Mills, G., Doheny, K., Tsai, Y. Y., Chen, W. V., Shete, S., Spitz, M. R., & Houlston, R. S. (2008). Genome-wide association scan of tag SNPs identifies a susceptibility locus for lung cancer at 15q25.1. Nature Genetics, 40(5), 616-622.
|Variable Name||Variable ID||Variable Description||dbGaP Mapping|
|PX030701010000||How old were you the first time you smoked more||N/A|
|PX030701010100||How old were you the first time you smoked more||N/A|
|PX030701020000||How old were you when you first started more||N/A|
|PX030701020100||How old were you when you first started more||N/A|
Age of Initiation of First Cigarette Use
February 6, 2009
Questions asking the respondent how old s/he was when s/he first smoked cigarettes and first smoked cigarettes regularly.
This measure assesses when the participant’s exposure to cigarette smoking began, often associated with level of nicotine addiction. When this measure is used in conjunction with the Tobacco - Age of Offset of Use measure for former smokers or current age for current smokers, the participant’s duration of smoking can be derived. Pack-years can also be derived from calculating the measure of amount smoked and duration.
tobacco, smoking, cigarette, nicotine, nicotine dependence, duration of smoking, pack years, National Survey on Drug Use and Health, NSDUH, gerontology, aging, geriatrics
|Protocol ID||Protocol Name|
|30701||Tobacco - Age of Initiation of Use - Adolescent|
|30702||Tobacco - Age of Initiation of Use - Adult|
|30703||Age of Initiation of First Cigarette Use - Adult|