Protocol - Quality of Life in Cancer Survivors - Active Treatment
Self-reported 30-item Likert style questions assessing quality of life and health, during the past week, in cancer patients during active treatment.
The European Organisation for the Research and Treatment of Cancer (EORTC) Quality of Life Questionnaire – Core 30 (QLQ-C30) © was developed to assess the quality of life in cancer patients. It is a copyrighted instrument, which has been translated and validated in over 110 languages and has been used in more than 3,000 studies worldwide. Presently QLQ-C30 Version 3.0 © is the most recent version and should be used for all new studies.
The instrument is freely available if your study is purely for academic use. For each study, researchers are required to have an Academic User Agreement in order to use EORTC protocols.
Studies with commercial sponsorship are required to have a Commercial User Agreement in order to use this protocol, and a fee is requested dependent on the number of patients in the study.
Personnel and Training Required
|Specialized requirements for biospecimen collection||No|
|Average time of greater than 15 minutes in an unaffected individual||No|
Mode of Administration
Ages 18 and older
This questionnaire was developed to assess the quality of life of cancer patients. It has been translated and validated into over 110 languages and was used in more than 3,000 studies worldwide.
|caDSR Common Data Elements (CDE)||Cancer Outcome Quality of Life Questionnaire – Core 30 (QLQ-C30) Assessment Text||7533688||CDE Browser|
Process and Review
Protocol Name from Source
Quality of Life in Cancer Patients European Organisation for the Research and Treatment of Cancer (EORTC) Quality of Life Questionnaire - Core 30 (QLQ-C30)
European Organisation for the Research and Treatment of Cancer (EORTC) Quality of Life Questionnaire – Core 30 (QLQ-C30)
Nolte S1, Liegl G2, Petersen MA3, Aaronson NK4, Costantini A5, Fayers PM6, Groenvold M7, Holzner B8, Johnson CD9, Kemmler G8, Tomaszewski KA10, Waldmann A11, Young TE12, Rose M13; EORTC Quality of Life Group. General population normative data for the EORTC QLQ-C30 health-related quality of life questionnaire based on 15,386 persons across 13 European countries, Canada and the Unites States. Eur J Cancer. 2019 Jan;107:153-163.
Quinten C, Coens C, Ghislain I, Zikos E, Sprangers M, Ringash J, Martinelli F, Ediebah D, Maringwa J, Reeve B, Greimel E, King M, Bjordal K, Flechtner H, Schmucker-Von Koch J, Taphoorn M, Weis J, Wildiers H, Velikova G, Bottomley A. The effects of age on health-related quality of life in cancer populations: A pooled analysis of randomized controlled trials using the European Organisation for Research and Treatment of Cancer (EORTC) QLQ-C30 involving 6024 cancer patients. Eur J Cancer 2015; 51 (18):2808-2819.
Scott NW, Etta JA, Aaronson NK, Bottomley A, Fayers PM, Groenvold M, Koller M, Kulis D, Marais D, Petersen MA, Sprangers M. An evaluation of the response category translations of the EORTC QLQ-C30 questionnaire. Qual Life Res 2013; 22:1483-1490.
Zeng L, Chow E, Zhang L, Tseng LM, Hou M-F, Fairchild A, Vassiliou V, Jesus-Garcia R, Alm El-Din MA, Kumar A, Forges F, Chu Chie W, Bedar G, Bottomley A. An international prospective study establishing minimal clinically important differences in the EORTC QLQ-BM22 and QLQ-C30 in cancer patients with bone metastases. 2012.
Martinelli F, Quinten C, Maringwa JT, Coens C, Vercauteren J, Cleeland CS, Flechtner H, Gotay C, Greimel E, King M, Mendoza T, Osoba D, Reeve BB, Ringash J, Koch JS, Shi Q, Taphoorn MJ, Weis J, Bottomley A. Examining the relationships among health-related quality-of-life indicators in cancer patients participating in clinical trials: a pooled study of baseline EORTC QLQ-C30 data. Expert Rev Pharmacoecon Outcomes Res 2011.
Maringwa J, Quinten C, King M, Ringash J, Osoba D, Coens C, Martinelli F, Reeve BB, Gotay C, Greimel E, Flechtner H, Cleeland CS, Schmucker-Von Koch J, Weis J, Van Den Bent MJ, Stupp R, Taphoorn MJ, Bottomley A. Minimal clinically meaningful differences for the EORTCQLQ-C30 and EORTC QLQ-BN20 scales in brain cancer patients. Ann Oncol 2011.
|Variable Name||Variable ID||Variable Description||dbGaP Mapping|
Quality of Life in Cancer Survivors
December 17, 2020
Questionnaire assessing health-related quality of life in cancer survivors.
Concerns about health-related quality of life are important to cancer survivors and their families, as well as caregivers and care providers.
European Organisation for the Research and Treatment of Cancer (EORTC): Cancer Outcomes and Survivorship