Protocol - Exposure at Work and in Daily Life
The respondent is asked to complete a table of questions about exposures at work or during daily life. If the respondent answers "yes" to any of the exposures the number of years exposed to the substance is also requested.
The PhenX Working Group recommends that examples be provided for each substance in the protocol table. Here are some examples:
Chemicals/Acids/Solvents (e.g., spot removers, paint thinners, surface treatments)
Coal or Stone Dusts (e.g., dust from grinding, polishing, drilling, cutting stone)
Coal Tar/Pitch/Asphalt (e.g., repair and install commercial flat roofs and road work)
Diesel Engine Exhaust (e.g., jobs working near trucks and buses; homes near truck traffic; commuting with heavy truck traffic)
Dyes (e.g., work with aniline fabric dyes, hairdressers, some artists)
Formaldehyde (e.g., work with permanent press fabrics; some lab work)
Gasoline Exhaust (e.g., toll takers, driving jobs, crossing guards, residence near heavily traveled roads)
Pesticides/Herbicides (e.g., applicator jobs, florist, farm or ranch worker)
Textile Fibers/Dusts (e.g., manufacturing textiles, clothing, other products, seamstress)
Wood Dust (e.g., carpenter, cabinet maker, construction with wood)
X-rays/Radioactive Materials (e.g., radiology worker, chemotherapy, some hospital pharmacy, some researchers)
In your work or daily life, are (were) you regularly exposed to any of the following? If "yes," indicate the number of years exposed.
Number of years
Coal or Stone Dusts
Diesel Engine Exhaust
Protocol Name from Source:
Cancer Prevention Study II (CPS-II), Men’s Baseline Questionnaire, 1982
Personnel and Training Required
This question may be self-administered (as in the source protocol) or administered by an interviewer with a paper-and-pencil or computer-assisted interview.
The interviewer must be trained to conduct personal interviews with individuals from the general population. The interviewer must be trained and found to be competent (i.e., tested by an expert) at the completion of personal interviews.* The interviewer should be trained to prompt respondents further if a "don’t know" response is provided.
* There are multiple modes to administer this question (e.g., paper-and-pencil and computer-assisted interviews).
Either a paper-and-pencil or computer-assisted instrument may be used. If a computer-assisted instrument is used, computer software may be necessary to develop the instrument. The interviewer will require a laptop computer or handheld computer to administer a computer-assisted questionnaire.
|Specialized requirements for biospecimen collection||No|
|Average time of greater than 15 minutes in an unaffected individual||No|
Mode of Administration
Adult 18 +
This protocol was vetted against other protocols and preferred because it includes a broad range of exposures and captures length of time of the exposure. This is a very good screening type question.
|Common Data Elements (CDE)||Person Daily Life Exposure Text||2954148||CDE Browser|
|Logical Observation Identifiers Names and Codes (LOINC)||Environ exp work daily life proto||62520-2||LOINC|
Process and Review
The Expert Review Panel #2 (ERP 2) reviewed the measures in the Demographics, Environmental Exposures, and Social Environments domains.
Guidance from ERP 2 includes:
• No significant changes to measure
Back-compatible: no changes to Data Dictionary
Previous version in Toolkit archive (link)
American Cancer Society. Cancer Prevention Study II (CPS-II), 1982. Men's Baseline Questionnaire. Question number 6.
|Variable Name||Variable ID||Variable Description||Version||dbGaP Mapping|
|PX060401_Exposure_Asbestos||PX060401010100||In your work or daily life, are (were) you regularly exposed to Asbestos?||4||N/A|
|PX060401_Exposure_Asbestos_Years||PX060401010200||How many years are (were) you regularly exposed to Asbestos?||4||N/A|
|PX060401_Exposure_Coal_Dust||PX060401030100||In your work or daily life, are (were) you regularly exposed to Coal or Stone Dusts?||4||N/A|
|PX060401_Exposure_Coal_Dust_Years||PX060401030200||How many years are (were) you regularly exposed to Coal or Stone Dusts?||4||N/A|
|PX060401_Exposure_Coal_Tar||PX060401040100||In your work or daily life, are (were) you regularly exposed to Coal Tar/Pitch/Asphalt?||4||N/A|
|PX060401_Exposure_Coal_Tar_Years||PX060401040200||How many years are (were) you regularly exposed to Coal Tar/Pitch/Asphalt?||4||N/A|
|PX060401_Exposure_Diesel_Engine_Exhaust||PX060401050100||In your work or daily life, are (were) you regularly exposed to Diesel Engine Exhaust?||4||N/A|
|PX060401_Exposure_Diesel_Engine_Exhaust_Years||PX060401050200||How many years are (were) you regularly exposed to Diesel Engine Exhaust?||4||N/A|
|PX060401_Exposure_Dye||PX060401060100||In your work or daily life, are (were) you regularly exposed to Dyes?||4||N/A|
|PX060401_Exposure_Dye_Years||PX060401060200||How many years are (were) you regularly exposed to Dyes?||4||N/A|
|PX060401_Exposure_Formaldehyde||PX060401070100||In your work or daily life, are (were) you regularly exposed to Formaldehyde?||4||N/A|
|PX060401_Exposure_Formaldehyde_Years||PX060401070200||How many years are (were) you regularly exposed to Formaldehyde?||4||N/A|
|PX060401_Exposure_Gasoline_Exhaust||PX060401080100||In your work or daily life, are (were) you regularly exposed to Gasoline Exhaust?||4||N/A|
|PX060401_Exposure_Gasoline_Exhaust_Years||PX060401080200||How many years are (were) you regularly exposed to Gasoline Exhaust?||4||N/A|
|PX060401_Exposure_Pesticides_Herbicides||PX060401090100||In your work or daily life, are (were) you regularly exposed to Pesticides/Herbicides?||4||N/A|
|PX060401_Exposure_Pesticides_Herbicides_Years||PX060401090200||How many years are (were) you regularly exposed to Pesticides/Herbicides?||4||N/A|
|PX060401_Exposure_Radioactive_Materials||PX060401120100||In your work or daily life, are (were) you regularly exposed to X-rays/Radioactive Materials?||4||N/A|
|PX060401_Exposure_Radioactive_Materials_Years||PX060401120200||How many years are (were) you regularly exposed to X-rays/Radioactive Materials?||4||N/A|
|PX060401_Exposure_Solvent||PX060401020100||In your work or daily life, are (were) you regularly exposed to Chemicals/Acids/Solvents?||4||Variable Mapping|
|PX060401_Exposure_Solvent_Years||PX060401020200||How many years are (were) you regularly exposed to Chemicals/Acids/Solvents?||4||N/A|
|PX060401_Exposure_Textile_Fiber_Dust||PX060401100100||In your work or daily life, are (were) you regularly exposed to Textile Fibers/Dusts?||4||N/A|
|PX060401_Exposure_Textile_Fiber_Dust_Years||PX060401100200||How many years are (were) you regularly exposed to Textile Fibers/Dusts?||4||N/A|
|PX060401_Exposure_Wood_Dust||PX060401110100||In your work or daily life, are (were) you regularly exposed to Wood Dust?||4||N/A|
|PX060401_Exposure_Wood_Dust_Years||PX060401110200||How many years are (were) you regularly exposed to Wood Dust?||4||N/A|
Exposure at Work and in Daily Life
May 31, 2016
A series of questions about being exposed to environmental substances at work or during daily activities
Some people may be exposed to known environmental contaminants during their daily activities or at work. These hazardous substances can cause a broad range of health ailments such as cancer, or cardiac, pulmonary, nervous, and reproductive system problems. By identifying these exposures and the length of time of the exposure, researchers can conduct a better assessment of the environmental causes of illness.
Environmental exposures, American Cancer Society, ACS work exposures, asbestos, chemicals, acids, solvents, diesel engine exhaust, gasoline engine exhaust, dust, dyes, formaldehyde, pesticides, herbicides, fibers, X-rays, radioactive material