Protocol - Frailty
Related Protocols:
Essential Protocols:
Description:
The SOF Frailty Index is an assessment of frailty based on an individual's weight change over the past three years, physical ability to perform five chair stands without using arms for support, and energy level. If the individual meets two of the three criteria (weight loss of 5% or more, inability to do chair stands, low/lack of energy), the individual is considered frail.
Specific Instructions:
Frailty can occur at younger ages than the traditional 65-year cutpoint for "older" and certainly does not need to be restricted to the SOF age (69 years of age and older).
Protocol:
Weight loss
- What was your weight 3 years ago? __ __ __ lbs
- What is your weight today? __ __ __ lbs
- [Interviewer/computer: calculate weight loss percentage] Change in weight (Q1-Q2)/weight 3 years ago (Q1)
= ___ __ % loss
Ability to do 5 chair stands
4. [Interviewer: Ask respondent to sit in chair, then rise up without using arms, repeat 4 more times.] Was respondent able to do chair stands without assistance? Yes or No
Energy level
5. Do you feel full of energy? Yes or No
Scoring
Q1. Score = 1 if weight loss ? 5%, otherwise, score = 0
Q2. Score = 1 if unable to do chair stands without assistance (No), otherwise, score = 0
Q3. Score = 1, if No, otherwise, score = 0
If summed score is 2 or 3, respondent is frail;
if score is 1 respondent is pre-frail;
if score is 0, respondent is robust.
Protocol Name from Source:
Study of Osteoporotic Fractures (SOF) Frailty Index
Availability:
Personnel and Training Required
The interviewer must be trained to conduct personal interviews with individuals from the general population. The interviewer must be trained and found to be competent (i.e., tested by an expert) at the completion of personal interviews. The interviewer should be trained to prompt respondents further if a "don't know" response is provided.
Equipment Needs
The PhenX Working Group acknowledges that these questions can be administered in a computerized or noncomputerized format (i.e., paper-and-pencil instrument). Computer software is necessary to develop computer-assisted instruments. The interviewer will require a laptop computer/handheld computer to administer a computer-assisted questionnaire. Chair for chair standsRequirements
Requirement Category | Required |
---|---|
Major equipment | No |
Specialized training | No |
Specialized requirements for biospecimen collection | No |
Average time of greater than 15 minutes in an unaffected individual | No |
Mode of Administration
Interviewer-administered questionnaire
Life Stage:
Pregnancy
Participants:
69 years of age and older
Selection Rationale
This well-established protocol has been used on a large prospective cohort study of older adults.
Language
English
Standards
Standard | Name | ID | Source |
---|---|---|---|
Common Data Elements (CDE) | Osteoporosis Study of Osteoporotic Fractures Frailty Index Assessment Score | 6360511 | CDE Browser |
Derived Variables
None
Process and Review
The Expert Review Panel has yet to review this measure.
Source
National Institute on Aging, Study of Osteoporotic Fractures (SOF) Frailty Index
General References
Ensrud, K. E., Ewing, S. K., Taylor, B. C., Fink, H. A., Cawthon, P. M., Stone, K. L., ... Cummings, S. R. (2008). Comparison of 2 frailty indexes for prediction of falls, disability, fractures, and death in older women. Archives of Internal Medicine,168(4), 382-9
Ensrud, K. E., Ewing, S. K., Cawthon, P. M., Fink, H. A., Taylor, B. C., Cauley, J. A., ... Osteoporotic Fractures in Men Research Group. (2009). A comparison of frailty indexes for the prediction of falls, disability, fractures, and mortality in older men. Journal of the American Geriatric Society, 57(3), 492-498.
Protocol ID:
251001
Variables:
Export VariablesVariable Name | Variable ID | Variable Description | Version | dbGaP Mapping |
---|
Measure Name:
Frailty
Release Date:
N/A
Definition
Declines in physiologic complexity or reserve in body systems, leading to loss of homeostatic capability to withstand stressors and resulting vulnerabilities.
Purpose
Frailty is associated with weakness and the inability to perform normal daily activities, particularly in older adults. Frailty leads to increased morbidity and mortality.
Keywords
Activities of Daily Living, ADLs, Frailty Index, Study of Osteoporotic Fractures (SOF), weakness, geriatrics, falls, National Institute on Aging, NIA, gerontology, aging