Protocol - Ovulation History

Description

These self-administered questions ask about menstruation and pregnancy history. Female respondents are asked about age at first menstruation, onset and cause of menopause, and pregnancy history and outcomes.

Specific Instructions

These questions should only be asked of women.

Availability

Available

Download PDF

Protocol

Menstrual History

1. Age at First Menstrual Period:

2. Have you had a menstrual period within the last year?

[ ] Yes

[ ] No → Age at last menstrual period:

3. Cause of Menopause:

[ ] natural

[ ] chemotherapy, medication induced

[ ] surgery on reproductive organs

[ ] other:

Pregnancies

4. Have you ever been pregnant?

[ ] Yes

[ ] No

Pregnancy	Date of End of Preg.	Outcome				Breast Feeding
Pregnancy	Date of End of Preg.	*Live birth*	*Stillborn*	*Miscarriage*	*Induced abortion*	Yes/No	Months of breast feeding
(Example)	11/13/1994	2 (twins)				Yes	3
(Example)	2/1996			1		-	-
1
2
3
4
5
6

5. Age at first birth:

Personnel and Training Required

None

Equipment Needs

None

Requirements

Requirement Category	Required
Major equipment	No
Specialized training	No
Specialized requirements for biospecimen collection	No
Average time of greater than 15 minutes in an unaffected individual	No

Mode of Administration

Self-administered questionnaire

Lifestage

Adult

Participants

Women, ages 18 years old and above

Selection Rationale

Ovulation history is associated with some female cancers. The Working Group selected this protocol because it includes major reproductive landmarks relevant to female reproductive cancers. A substantial amount of information is gathered in a short protocol.

Language

Chinese, English

Standards

Standard	Name	ID	Source
Logical Observation Identifiers Names and Codes (LOINC)	Ovulation hx proto	62567-3	LOINC
Human Phenotype Ontology	Neoplasm	HP:0002664	HPO
caDSR Form	PhenX PX070501 - Ovulation History	5872780	caDSR Form

Derived Variables

None

Process and Review

Not applicable.

Protocol Name from Source

University of Pennsylvania, Cancer Risk Evaluation Program, Health History Questionnaire, 9/2006

Source

University of Pennsylvania, Abramson Cancer Center, Cancer Risk Evaluation Program, Health History Questionnaire 9/2006, page 7.

General References

None

Protocol ID

70501

Variables

Export Variables

Variable Name	Variable ID	Variable Description	dbGaP Mapping
PX070501_Breast_Feeding_1
	PX070501040204	Breast Feeding?	N/A
PX070501_Breast_Feeding_2
	PX070501040304	Breast Feeding?	N/A
PX070501_Breast_Feeding_3
	PX070501040404	Breast Feeding?	N/A
PX070501_Breast_Feeding_4
	PX070501040504	Breast Feeding?	N/A
PX070501_Breast_Feeding_5
	PX070501040604	Breast Feeding?	N/A
PX070501_Breast_Feeding_6
	PX070501040704	Breast Feeding?	N/A
PX070501_Breast_Feeding_Months_1
	PX070501040205	Months of breast feeding?	N/A
PX070501_Breast_Feeding_Months_2
	PX070501040305	Months of breast feeding?	N/A
PX070501_Breast_Feeding_Months_3
	PX070501040405	Months of breast feeding?	N/A
PX070501_Breast_Feeding_Months_4
	PX070501040505	Months of breast feeding?	N/A
PX070501_Breast_Feeding_Months_5
	PX070501040605	Months of breast feeding?	N/A
PX070501_Breast_Feeding_Months_6
	PX070501040705	Months of breast feeding?	N/A
PX070501_Ever_Pregnancy
	PX070501040100	Have you ever been pregnant?	Variable Mapping
PX070501_First_Birth_Age
	PX070501050000	Age at first birth?	Variable Mapping
PX070501_Menopause_Cause
	PX070501030000	Cause of Menopause?	Variable Mapping
PX070501_Menopause_Cause_Other
	PX070501030100	Cause of Menopause?	Variable Mapping
PX070501_Menstrual_Period_First_Age
	PX070501010000	Age at First Menstrual Period?	Variable Mapping
PX070501_Menstrual_Period_Last_Age
	PX070501020200	Age at last menstrual period?	Variable Mapping
PX070501_Menstrual_Period_Within_Last_Year
	PX070501020100	Have you had a menstrual period within the more last year? show less	Variable Mapping
PX070501_Pregnancy_End_Date_1
	PX070501040201	Date of End of Preg?	Variable Mapping
PX070501_Pregnancy_End_Date_2
	PX070501040301	Date of End of Preg?	N/A
PX070501_Pregnancy_End_Date_3
	PX070501040401	Date of End of Preg?	N/A
PX070501_Pregnancy_End_Date_4
	PX070501040501	Date of End of Preg?	N/A
PX070501_Pregnancy_End_Date_5
	PX070501040601	Date of End of Preg?	N/A
PX070501_Pregnancy_End_Date_6
	PX070501040701	Date of End of Preg?	N/A
PX070501_Pregnancy_Outcome_1
	PX070501040202	Outcome of Pregnancy?	Variable Mapping
PX070501_Pregnancy_Outcome_2
	PX070501040302	Outcome of Pregnancy?	N/A
PX070501_Pregnancy_Outcome_3
	PX070501040402	Outcome of Pregnancy?	N/A
PX070501_Pregnancy_Outcome_4
	PX070501040502	Outcome of Pregnancy?	N/A
PX070501_Pregnancy_Outcome_5
	PX070501040602	Outcome of Pregnancy?	N/A
PX070501_Pregnancy_Outcome_6
	PX070501040702	Outcome of Pregnancy?	N/A
PX070501_Pregnancy_Outcome_Number_Birth_1
	PX070501040203	Number of birth?	N/A
PX070501_Pregnancy_Outcome_Number_Birth_2
	PX070501040303	Number of birth?	N/A
PX070501_Pregnancy_Outcome_Number_Birth_3
	PX070501040403	Number of birth?	N/A
PX070501_Pregnancy_Outcome_Number_Birth_4
	PX070501040503	Number of birth?	N/A
PX070501_Pregnancy_Outcome_Number_Birth_5
	PX070501040603	Number of birth?	N/A
PX070501_Pregnancy_Outcome_Number_Birth_6
	PX070501040703	Number of birth?	N/A

Cancer

Measure Name

Ovulation History

Release Date

December 30, 2009

Definition

Measure to assess ovulation history, including pregnancy and breast-feeding history

Purpose

The purpose of this measure is to assess a woman's ovulation history, including pregnancy and breast-feeding history. It is important to measure because of the association between ovulation history and some female cancers.

Keywords

cancer, ovulation, menstruation, pregnancy history, risk, breast feeding, Cancer Risk Evaluation Program (CREP)

Measure Protocols

Protocol ID	Protocol Name
70501	Ovulation History

Publications

There are no publications listed for this protocol.

Mapping for PX070501_Ever_Pregnancy

dbGAP Study	dbGAP Variable	dbGAP Variable Description
Atherosclerosis Risk in Communities (ARIC) Cohort	phv00091347	EVER BEEN PREGNANT Q13
Atherosclerosis Risk in Communities (ARIC) Cohort	phv00203063	Have you ever been pregnant? Q13 [AFU Medical History Form, AMH]
CARDIA Cohort	phv00113011	EVER BEEN PREGNANT
CARDIA Cohort	phv00114359	EVER PREGNANT. Q 6
CARDIA Cohort	phv00115480	EVER BEEN PREGNANT. Q 14
CARDIA Cohort	phv00117096	EVER BEEN PREGNANT. Q 38
CARDIA Cohort	phv00118582	EVER BEEN PREGNANT. Q 45
CARDIA Cohort	phv00119975	EVER BEEN PREGNANT. Q 43
Framingham Cohort	phv00020893	HAVE YOU EVER BEEN PREGNANT?
Multi-Ethnic Study of Atherosclerosis (MESA) Cohort	phv00083018	EVER BEEN PREGNANT
Multi-Ethnic Study of Atherosclerosis (MESA) Cohort	phv00085251	EVER BEEN PREGNANT
Multi-Ethnic Study of Atherosclerosis (MESA) Cohort	phv00087168	EVER BEEN PREGNANT
NIA Long Life Family Study (LLFS)	phv00163294	Ever been pregnant?
The Role of the Gut Microbiota in Ulcerative Colitis	phv00091215	Ever pregnant
Whole Genome Association Study of Bipolar Disorder	phv00052035	B8 Ever pregnant, (African American participants). DIGS4
Whole Genome Association Study of Bipolar Disorder	phv00011753	B8. Have you ever been pregnant? (Participants with European ancestry). DIGS2
Whole Genome Association Study of Bipolar Disorder	phv00017201	B8. Have you ever been pregnant? (Participants with European ancestry). DIGS4
Women's Health Initiative	phv00078618	Ever been pregnant

Mapping for PX070501_First_Birth_Age

dbGAP Study	dbGAP Variable	dbGAP Variable Description
Pediatric Cardiac Genetics Consortium (PCGC)	phv00181020	Birth age
Pediatric Cardiac Genetics Consortium (PCGC)	phv00181075	Birth age

Mapping for PX070501_Menopause_Cause

dbGAP Study	dbGAP Variable	dbGAP Variable Description
Atherosclerosis Risk in Communities (ARIC) Cohort	phv00094047	CAUSE OF MENOPAUSE Q9
Atherosclerosis Risk in Communities (ARIC) Cohort	phv00096016	CAUSE OF MENOPAUSE Q9
Atherosclerosis Risk in Communities (ARIC) Cohort	phv00096068	CAUSE OF MENOPAUSE Q8
Atherosclerosis Risk in Communities (ARIC) Cohort	phv00096123	CAUSE OF MENOPAUSE Q8
Framingham Cohort	phv00007722	MENOPAUSE: CAUSE PERIOD STOPPED
Framingham Cohort	phv00008424	MENOPAUSE: CAUSE FOR PERIODS TO STOP
Framingham Cohort	phv00011076	CAUSE OF CESSATION OF MENSES
Framingham Cohort	phv00036420	Cause periods stopped
Framingham Cohort	phv00070738	Cause Periods Stopped
GENEVA: The Atherosclerosis Risk in Communities (ARIC) Study	phv00080513	Cause of menopause (visit 1)

Mapping for PX070501_Menopause_Cause_Other

dbGAP Study	dbGAP Variable	dbGAP Variable Description
Framingham Cohort	phv00007722	MENOPAUSE: CAUSE PERIOD STOPPED
Framingham Cohort	phv00008424	MENOPAUSE: CAUSE FOR PERIODS TO STOP
Framingham Cohort	phv00011076	CAUSE OF CESSATION OF MENSES
Framingham Cohort	phv00036420	Cause periods stopped
Framingham Cohort	phv00070738	Cause Periods Stopped
GENEVA: The Atherosclerosis Risk in Communities (ARIC) Study	phv00080513	Cause of menopause (visit 1)

Mapping for PX070501_Menstrual_Period_First_Age

dbGAP Study	dbGAP Variable	dbGAP Variable Description
CARDIA Cohort	phv00118701	AGE AT MENARCHE
Framingham Cohort	phv00020887	HOW OLD WERE YOU WHEN YOU HAD YOUR FIRST MENSTRUAL PERIOD (MENSES)?
Framingham Cohort	phv00007725	MENOPAUSE: AGE PERIODS STARTED
Framingham Cohort	phv00164594	Age in years at menarche
Genes and Blood Clotting Study (GABC)	phv00124376	At what age did you have your first period?
GWAS for Genetic Determinants of Bone Fragility	phv00065517	Age of menarche
GWAS of Breast Cancer in the African Diaspora	phv00172020	Age at menarche
Jackson Heart Study (JHS) Cohort	phv00128259	1: Age when menstrual period started(age)?
Jackson Heart Study (JHS) Cohort	phv00181229	Age in years at menarche (start of menstruation)
Jackson Heart Study (JHS) Cohort	phv00165357	Age in years at menarche
NHLBI ARIC Candidate Gene Association Resource (CARe)	phv00190336	Age in years at menarche (start of menstruation)
NHLBI Cleveland Family Study (CFS) Candidate Gene Association Resource (CARe)	phv00123230	75 At what age did your menstrual periods begin?
NHLBI GO-ESP: Heart Cohorts Exome Sequencing Project (ARIC)	phv00163973	Age in years at menarche
NHLBI GO-ESP: Heart Cohorts Exome Sequencing Project (CARDIA)	phv00190580	Age in years at menarche
PAGE: Multiethnic Cohort (MEC)	phv00163131	Age at menarche
The Vaginal Microbiome: Disease, Genetics and the Environment	phv00090425	How old were you when you got your first period?
Women's Health Initiative	phv00078608	Age at first period

Mapping for PX070501_Menstrual_Period_Last_Age

dbGAP Study	dbGAP Variable	dbGAP Variable Description
Atherosclerosis Risk in Communities (ARIC) Cohort	phv00096170	AGE WHEN MENOPAUSE BEGAN Q7
Atherosclerosis Risk in Communities (ARIC) Cohort	phv00096015	AGE WHEN MENOPAUSE BEGAN Q8
Atherosclerosis Risk in Communities (ARIC) Cohort	phv00094332	AGE MENOPAUSE BEGAN Q19
Atherosclerosis Risk in Communities (ARIC) Cohort	phv00094046	AGE WHEN MENOPAUSE BEGAN Q8
Atherosclerosis Risk in Communities (ARIC) Cohort	phv00094007	Age at natural menopause
CARDIA Cohort	phv00120559	AGE PERIODS STOPPED, PAST 12 MONTHS. Q 10
Cardiovascular Health Study (CHS) Cohort	phv00100351	AGE AT MENOPAUSE
Framingham Cohort	phv00008423	MENOPAUSE: AGE PERIOD STOPPED
Framingham Cohort	phv00036428	STOP_AGE approximated
Framingham Cohort	phv00036419	Age periods stopped
Framingham Cohort	phv00007721	MENOPAUSE: AGE PERIOD STOPPED
GENEVA: The Atherosclerosis Risk in Communities (ARIC) Study	phv00080512	Age when menopause began (visit 1)
GENEVA: The Atherosclerosis Risk in Communities (ARIC) Study	phv00080474	Age at natural menopause
GWAS of Breast Cancer in the African Diaspora	phv00172024	Age at menopause
Jackson Heart Study (JHS) Cohort	phv00128267	9: Age when you stopped menstrual?
Multi-Ethnic Study of Atherosclerosis (MESA) Cohort	phv00087184	AGE OF MENOPAUSE
Multi-Ethnic Study of Atherosclerosis (MESA) Cohort	phv00085267	AGE WENT THROUGH MENOPAUSE
Multi-Ethnic Study of Atherosclerosis (MESA) Cohort	phv00083034	AGE WENT THROUGH MENOPAUSE
NHLBI Cleveland Family Study (CFS) Candidate Gene Association Resource (CARe)	phv00122154	Age at menopause (A)
NHLBI GO-ESP: Heart Cohorts Exome Sequencing Project (ARIC)	phv00190422	Age in years at menopause
NHLBI GO-ESP: Heart Cohorts Exome Sequencing Project (CHS)	phv00165190	AGE IN YEARS AT MENOPAUSE
NHLBI GO-ESP: Heart Cohorts Exome Sequencing Project (MESA)	phv00178057	AGE IN YEARS AT MENOPAUSE
NHLBI GO-ESP: Women's Health Initiative Exome Sequencing Project (WHI) - WHISP	phv00165280	AGE IN YEARS AT MENOPAUSE
NIA Long Life Family Study (LLFS)	phv00163297	Age of menopause was reached
PAGE: Multiethnic Cohort (MEC)	phv00163132	Age stopped menstruating: reported at baseline
The Vaginal Microbiome: Disease, Genetics and the Environment	phv00090436	How old were you when your periods stopped?
Women's Health Initiative	phv00110722	Age at menopause

Mapping for PX070501_Menstrual_Period_Within_Last_Year

dbGAP Study	dbGAP Variable	dbGAP Variable Description
CARDIA Cohort	phv00120559	AGE PERIODS STOPPED, PAST 12 MONTHS. Q 10
Diet, Genetic Factors, and the Gut Microbiome in Crohn's Disease	phv00090936	If female, has the patient had a menstrual period in the last year?
Framingham Cohort	phv00007720	MENOPAUSE: PERIODS STOPPED 1 YR OR MORE
Framingham Cohort	phv00008422	MENSTRUAL PERIODS HAVE STOPPED ONE YEAR OR MORE
Framingham Cohort	phv00009727	MENSTRUAL PERIODS HAVE STOPPED ONE YEAR OR MORE
Framingham Cohort	phv00010220	MENSTRUAL PERIODS HAVE STOPPED ONE YEAR OR MORE
Framingham Cohort	phv00011075	AGE AT WHICH PERIODS HAVE STOPPED FOR ONE YEAR OR MORE
Framingham Cohort	phv00020903	HAVE YOUR PERIODS STOPPED (FOR ONE YEAR OR MORE)? (HAVE YOU REACHED MENOPAUSE?)
Framingham Cohort	phv00070737	Age When Periods Reported Stopped For One Year Or More

Mapping for PX070501_Pregnancy_End_Date_1

dbGAP Study	dbGAP Variable	dbGAP Variable Description
CARDIA Cohort	phv00115071	DATE PREGNANCY ENDED. Q 3
CARDIA Cohort	phv00116334	DATE PREGNANCY ENDED
CARDIA Cohort	phv00117509	DATE PREGNANCY ENDED. Q 3
CARDIA Cohort	phv00119581	DATE PREGNANCY ENDED. Q 3
CARDIA Cohort	phv00120651	DATE PREGNANCY ENDED. Q 3
DCCT-EDIC Clinical Trial and Follow-up of Persons with Type 1 Diabetes	phv00032008	Date of (pregnancy) termination
DCCT-EDIC Clinical Trial and Follow-up of Persons with Type 1 Diabetes	phv00048961	O3b. Female/ reproductive. Deidentified date of termination (Month/Day/Year)
DCCT-EDIC Clinical Trial and Follow-up of Persons with Type 1 Diabetes	phv00049379	O3b. Female/ reproductive. Deidentified date of termination (Month/Day/Year)

Mapping for PX070501_Pregnancy_Outcome_1

dbGAP Study	dbGAP Variable	dbGAP Variable Description
NICHD Genomic and Proteomic Network for Preterm Birth Research (GPN)	phv00200684	If the infant is not live born, code infant outcome

Protocol - Ovulation History

Essential Protocols:

Description

Specific Instructions

Availability

Protocol

Personnel and Training Required

Equipment Needs

Requirements

Mode of Administration

Lifestage

Participants

Selection Rationale

Language

Standards

Derived Variables

Process and Review

Protocol Name from Source

Source

General References

Protocol ID

Variables

Measure Name

Release Date

Definition

Purpose

Keywords

Measure Protocols

Publications