Protocol - Perimenopausal Symptoms
Description
The Greene Climacteric Scale is a twenty-one–item, self-administered questionnaire that captures the symptoms that occur in perimenopause. Each item is rated on a Likert-style scale from “Not at all” (0) to “Extremely” (3). Scores can be derived in six symptom categories: Psychological, Anxiety, Depressed Mood, Vasomotor, Somatic, and Sexuality.
Specific Instructions
The Sickle Cell Disease Genitourinary Working Group notes some questions in this assessment are sensitive. Investigators should provide a private space for completing assessments and to be prepared to offer appropriate support.
Availability
This protocol is freely available; permission not required for use.
Protocol
The Greene Climacteric Scale
Please indicate the extent to which you are bothered at the moment by any of these symptoms by placing a tick in the appropriate box.
| SYMPTOMS | Not at all | A little | Quite a bit | Extremely | Score 0-3 |
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Psychological (P), sum items 1-11 = __________
Somatic (S), sum items 12-18 = _____
Vasomotor (V), sum items 19-20 = _____
Anxiety (A), sum items 1-6 = ______
Depressed Mood (D), sum items 7-11 = ______
Sexuality, item 21 = ______
Personnel and Training Required
None
Equipment Needs
None
Requirements
| Requirement Category | Required |
|---|---|
| Major equipment | No |
| Specialized training | No |
| Specialized requirements for biospecimen collection | No |
| Average time of greater than 15 minutes in an unaffected individual | No |
Mode of Administration
Self-administered questionnaire
Lifestage
Adult, Senior
Participants
Adult females who are perimenopausal
Selection Rationale
The Greene Climacteric Scale is a brief, validated, self-administered scale that is easy to use and score.
Language
English
Standards
| Standard | Name | ID | Source |
|---|
Derived Variables
None
Process and Review
Not applicable.
Protocol Name from Source
The Greene Climacteric Scale
Source
Greene J. G. (1998). Constructing a standard climacteric scale. Maturitas, 29(1), 25–31. https://doi.org/10.1016/S0378-5122(98)00025-5
General References
Carpenter, J. S., Sheng, Y., Pike, C., Elomba, C. D., Alwine, J. S., Chen, C. X., & Tisdale, J. E. (2022). Correlates of palpitations during menopause: A scoping review. Women’s Health, 18. https://doi.org/10.1177/17455057221112267
Sourouni, M., Zangger, M., Honermann, L., Foth, D., & Stute, P. (2021). Assessment of the climacteric syndrome: A narrative review. Archives of Gynecology and Obstetrics, 304(4), 855–862. https://doi.org/10.1007/s00404-021-06139-y
Protocol ID
880401
Variables
Export Variables| Variable Name | Variable ID | Variable Description | dbGaP Mapping | |
|---|---|---|---|---|
| PX880401_Perimenopausal_Symptoms_Attacks_Panic | ||||
| PX880401050000 | Attacks of panic | N/A | ||
| PX880401_Perimenopausal_Symptoms_Breathing_Difficulties | ||||
| PX880401180000 | Breathing difficulties | N/A | ||
| PX880401_Perimenopausal_Symptoms_Crying_Spells | ||||
| PX880401100000 | Crying spells | N/A | ||
| PX880401_Perimenopausal_Symptoms_Difficulty_Concentrating | ||||
| PX880401060000 | Difficulty in concentrating | N/A | ||
| PX880401_Perimenopausal_Symptoms_Difficulty_Sleeping | ||||
| PX880401030000 | Difficulty in sleeping | N/A | ||
| PX880401_Perimenopausal_Symptoms_Excitable | ||||
| PX880401040000 | Excitable | N/A | ||
| PX880401_Perimenopausal_Symptoms_Feel_Dizzy_Faint | ||||
| PX880401120000 | Feeling dizzy or faint | N/A | ||
| PX880401_Perimenopausal_Symptoms_Feel_Tense_Nervous | ||||
| PX880401020000 | Feeling tense or nervous | N/A | ||
| PX880401_Perimenopausal_Symptoms_Feel_Tired_Lack_Energy | ||||
| PX880401070000 | Feeling tired or lacking in energy | N/A | ||
| PX880401_Perimenopausal_Symptoms_Feel_Unhappy_Depressed | ||||
| PX880401090000 | Feeling unhappy or depressed | N/A | ||
| PX880401_Perimenopausal_Symptoms_Headaches | ||||
| PX880401150000 | Headaches | N/A | ||
| PX880401_Perimenopausal_Symptoms_Heart_Beating_Quickly_Strongly | ||||
| PX880401010000 | Heart beating quickly or strongly | N/A | ||
| PX880401_Perimenopausal_Symptoms_Hot_Flushes | ||||
| PX880401190000 | Hot flushes | N/A | ||
| PX880401_Perimenopausal_Symptoms_Irritability | ||||
| PX880401110000 | Irritability | N/A | ||
| PX880401_Perimenopausal_Symptoms_Loss_Feeling_Hands_Feet | ||||
| PX880401170000 | Loss of feeling in hands or feet | N/A | ||
| PX880401_Perimenopausal_Symptoms_Loss_Interest | ||||
| PX880401080000 | Loss of interest in most things | N/A | ||
| PX880401_Perimenopausal_Symptoms_Loss_Interest_Sex | ||||
| PX880401210000 | Loss of interest in sex | N/A | ||
| PX880401_Perimenopausal_Symptoms_Muscle_Joint_Pains | ||||
| PX880401160000 | Muscle and joint pains | N/A | ||
| PX880401_Perimenopausal_Symptoms_Parts_Body_Feel_Numb_Tingling | ||||
| PX880401140000 | Parts of body feel numb or tingling | N/A | ||
| PX880401_Perimenopausal_Symptoms_Pressure_Tightness_Head_Body | ||||
| PX880401130000 | Pressure or tightness in head or body | N/A | ||
| PX880401_Perimenopausal_Symptoms_Sweating_Night | ||||
| PX880401200000 | Sweating at night | N/A | ||