Design considerations for a pilot trial using a novel approach for evaluating smoking-cessation medication in methadone-maintained smokers.
| Study Name | Design considerations for a pilot trial using a novel approach for evaluating smoking-cessation medication in methadone-maintained smokers. |
|---|---|
| Study Acronym | |
| Funding Agency | Pfizer |
| Primary Research Focus | The prevalence of smoking in methadone-maintained (MM) patients is over 80% and smoking-abstinence rates are strikingly low, even with the use of first-line smoking-cessation medications. Research has found that cigarettes increase the reinforcing properties of methadone; this interaction may be an additional, daily, challenge to smoking cessation in MM-smokers. This paper describes a novel approach in which patients who experience a particular barrier to achieving smoking abstinence are selected, and the impact of smoking-cessation medications on the identified barrier is evaluated. |
| Study Design Name | |
| Number Participants | <100 |
| Study Website | |
| Protocol Ids | 230102 |
| Grant Number | |
| Citation Link | https://www.ncbi.nlm.nih.gov/pubmed/26944021 |