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Marshfield Personalized Medicine Research Project

Study Name Marshfield Personalized Medicine Research Project
Study Acronym PMRP
Funding Agency NHGRI NIH HHS,NCATS NIH HHS,NHLBI NIH HHS,NLM NIH HHS,NHLBI NIH HHS,NHGRI NIH HHS,NIEHS NIH HHS,NLM NIH HHS,NIAID NIH HHS,NHGRI NIH HHS,NLM NIH HHS,NLM NIH HHS
Primary Research Focus The PLatform for the Analysis, Translation, and Organization of large-scale data (PLATO), a software tool equipped to handle multi-omic data for hundreds of thousands of samples to explore complexity using genetic interactions, environment-wide association studies and gene–environment interactions, phenome-wide association studies, as well as copy number and rare variant analyses. Using the data from the Marshfield Personalized Medicine Research Project, a site in the electronic Medical Records and Genomics Network, we apply each feature of PLATO to type 2 diabetes and demonstrate how PLATO can be used to uncover the complex etiology of common traits.
Study Design Name
Number Participants >1000
Study Website https://www.plato.de/en/
Protocol Ids 2, 030, 430, 201, 304, 010, 000, 000, 000, 000, 000
Grant Number U01 HG006385,UL1 TR000427,U19 HL065962,T32 LM012415,U01 HL065962,U01 HG006389,P30 ES013508,R01 LM010098,R01 AI116794,F31 HG008588,R01 LM009012,R01 LM010040
Citation Link https://www.ncbi.nlm.nih.gov/pubmed/29079728