| Study Name |
Marshfield Personalized Medicine Research Project |
| Study Acronym |
PMRP |
| Funding Agency |
NHGRI NIH HHS,NCATS NIH HHS,NHLBI NIH HHS,NLM NIH HHS,NHLBI NIH HHS,NHGRI NIH HHS,NIEHS NIH HHS,NLM NIH HHS,NIAID NIH HHS,NHGRI NIH HHS,NLM NIH HHS,NLM NIH HHS |
| Primary Research Focus |
The PLatform for the Analysis, Translation, and Organization of large-scale data (PLATO), a software tool equipped to handle multi-omic data for hundreds of thousands of samples to explore complexity using genetic interactions, environment-wide association studies and gene""environment interactions, phenome-wide association studies, as well as copy number and rare variant analyses. Using the data from the Marshfield Personalized Medicine Research Project, a site in the electronic Medical Records and Genomics Network, we apply each feature of PLATO to type 2 diabetes and demonstrate how PLATO can be used to uncover the complex etiology of common traits. |
| Study Design Name |
|
| Number Participants |
>1000 |
| Study Website |
https://www.plato.de/en/ |
| Protocol Ids |
20304, 30201, 30401, 31301, 60701, 121601 |
| Grant Number |
U01 HG006385,UL1 TR000427,U19 HL065962,T32 LM012415,U01 HL065962,U01 HG006389,P30 ES013508,R01 LM010098,R01 AI116794,F31 HG008588,R01 LM009012,R01 LM010040 |
| Citation Link |
https://www.ncbi.nlm.nih.gov/pubmed/29079728 |