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Protocol - Cognitive Function

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Description

The PROMIS® Cognitive Function v.2.0 - Short Form 6a is a six-item sub-set scale of the PROMIS® Cognitive Function item bank that assesses patient-perceived cognitive deficits.

Specific Instructions

Instruct participants to answer all of the items (i.e., questions or statements) presented. Some administrators may prefer to ask the same question of all respondents or of the same respondent over time, to enable a more direct comparability across people or time

All scores must be presented as t-scores not raw scores. The T-score is the standardized score with a mean of 50 and standard deviation of 10.

T-scores can be generated in three ways:

  1. Use a data collection tool that automatically calculates scores
  2. Use the free on-line HealthMeasures Scoring Service
  3. Score by hand using the Cognitive Function Scoring Manual Short Form 6a look-up table (see protocol)

Other notes:

  • Score-based Percentiles can be included as additional but not replacement information.
  • Higher scores indicate higher Cognitive Function.

The PhenX Working Group recommends this PROMIS® protocol. For additional information regarding PROMIS® instruments (including scoring, validity, and interpretation) please visit: www.healthmeasures.net. For specific information about this instrument, please visit: www.healthmeasures.net/index.php?option=com_instruments&view=measure&id=768&Itemid=992

Availability

Available

Protocol

Please respond to each question or statement by marking one box per row.

In the past 7 days...

Never Rarely
(Once)
Sometimes
(Two or three times)
Often
(About once a day)
Very Often
(Several times a day)

My thinking has been slow.

 [ ] 5  [ ] 4  [ ] 3  [ ] 2  [ ] 1

It has seemed like my brain was not working as well as usual...

 [ ] 5  [ ] 4  [ ] 3  [ ] 2  [ ] 1

I have had to work harder than usual to keep track of what I was doing..

 [ ] 5  [ ] 4  [ ] 3  [ ] 2  [ ] 1

I have had trouble shifting back and forth between different activities that require thinking...

 [ ] 5  [ ] 4  [ ] 3  [ ] 2  [ ] 1

I have had trouble concentrating...

 [ ] 5  [ ] 4  [ ] 3  [ ] 2  [ ] 1

I have had to work really hard to pay attention or I would make a mistake

 [ ] 5  [ ] 4  [ ] 3  [ ] 2  [ ] 1

Scoring Table:

Adult v2.0 – Cognitive Function 6a

Short Form Conversion Table

Raw Score

T-Score

SE*

6

23.13

4.25

7

26.64

3.28

8

28.55

3.05

9

30.18

2.84

10

31.58

2.72

11

32.85

2.64

12

34.04

2.59

13

35.17

2.57

14

36.28

2.57

15

37.37

2.57

16

38.45

2.57

17

39.53

2.58

18

40.63

2.59

19

41.74

2.60

20

42.87

2.62

21

44.04

2.63

22

45.23

2.64

23

46.47

2.67

24

47.77

2.71

25

49.17

2.79

26

50.72

2.94

27

52.49

3.14

28

54.69

3.51

29

57.60

4.04

30

63.17

5.75

*SE = Standard Error on T-score metric

Personnel and Training Required

None

Equipment Needs

The PhenX Working Group acknowledges that the questions can be administered in a computerized or noncomputerized format (i.e., paper-and-pencil instrument). Computer software is needed to administer the instrument.

Requirements
Requirement CategoryRequired
Major equipment No
Specialized training No
Specialized requirements for biospecimen collection No
Average time of greater than 15 minutes in an unaffected individual No
Mode of Administration

Self-administered questionnaire

Lifestage

Adult

Participants

Adults (ages 18+)

Selection Rationale

The PROMIS® protocols were tested and found to be reliable and comparable to established measures of these same content areas. Additionally, they are quick and easy to administer, either via paper and pencil or as a computer-based instrument. The cognitive function instrument is universal rather than disease specific. The Cancer Outcomes and Survivorship Working Group chose this protocol because it is a short, valid, reliable general instrument. The Functional Assessment of Cancer Therapy—Cognition (FACT-Cog), is a longer alternative specific to cancer populations.

Language

English, Other languages available at source

Standards
StandardNameIDSource
Derived Variables

None

Process and Review

Not Applicable

Protocol Name from Source

Patient-Reported Outcomes Measurement Information System (PROMIS®) - Cognitive Function v2.0 - Short Form 6a

Source

© 2020 Northwestern University, PROMIS® Short Form V2.0 – Cognition Function 6a ©.

General References

Lai, J.-S., Wagner, L.I., Jacobsen, P.B., & Cella, D. (2014). Self Reported Cognitive Concerns and Abilities: Two Sides of One Coin? Psycho-Oncology, 23(10), 1133-1141. doi.org/10.1002/pon.3522

Jensen RE, Potosky AL, Moinpour CM, et al. United States Population-Based Estimates of Patient-Reported Outcomes Measurement Information System Symptom and Functional Status Reference Values for Individuals With Cancer. J Clin Oncol. 2017;35(17):1913–1920. doi:10.1200/JCO.2016.71.4410

Jensen RE, Moinpour CM, Potosky AL, et al. Responsiveness of 8 Patient-Reported Outcomes Measurement Information System (PROMIS) measures in a large, community-based cancer study cohort. Cancer. 2017;123(2):327–335. doi:10.1002/cncr.30354

Protocol ID

320301

Variables
Export Variables
Variable Name Variable IDVariable DescriptiondbGaP Mapping
PX320301_Cognitive_Function_Past_Week_Brain_Not_Working
PX320301020000 In the past 7 days, it has seemed like my more
brain was not working as well as usual... show less
N/A
PX320301_Cognitive_Function_Past_Week_Thinking_Slow
PX320301010000 In the past 7 days, my thinking has been slow... N/A
PX320301_Cognitive_Function_Past_Week_Trouble_Concentrating
PX320301050000 In the past 7 days, I have had trouble more
concentrating... show less
N/A
PX320301_Cognitive_Function_Past_Week_Trouble_Multitasking
PX320301040000 In the past 7 days, I have had trouble more
shifting back and forth between different activities that require thinking... show less
N/A
PX320301_Cognitive_Function_Past_Week_Work_Harder_Keep_Track
PX320301030000 In the past 7 days, I have had to work more
harder than usual to keep track of what I was doing... show less
N/A
PX320301_Cognitive_Function_Past_Week_Work_Hard_Pay_Attention
PX320301060000 In the past 7 days, I have had to work more
really hard to pay attention or I would make a mistake... show less
N/A
Cancer Outcomes and Survivorship
Measure Name

Cognitive Function

Release Date

December 17, 2020

Definition

The PROMIS ® (Patient-Reported Outcomes Measurement Information System) Cognitive Function item bank assess patient-perceived cognitive deficits. Facets include mental acuity, concentration, verbal and nonverbal memory, verbal fluency, and perceived changes in cognitive functions. The extent to which cognitive impairments interfere with daily functioning, whether other people observe cognitive impairments, and the impact of cognitive dysfunction on quality of life are also assessed.

Purpose

This measure can be used to assess patient-perceived cognitive deficits and its impact on daily functioning.

Keywords

Cancer outcomes and survivorship, mental acuity, cognition deficits, PROMIS®, cognition, cognitive status

Measure Protocols
Protocol ID Protocol Name
320301 Cognitive Function
Publications

There are no publications listed for this protocol.