Protocol - Depressive Symptoms - Adult
The Quick Inventory of Depressive Symptoms (QIDS) is a self-administered questionnaire; QIDS includes 16 items that capture the severity of nine depressive symptoms in the last 7 days. Each item is rated on a 4-point scale (0-3); total scores range from 0-27, with higher scores indicating more severe depression.
Quick Inventory of Depressive Symptoms (QIDS)
Please indicate the one response to each item that best describes you for the past seven days.
1. Falling Asleep:
[ ] 0 I never take longer than 30 minutes to fall asleep.
[ ] 1 I take at least 30 minutes to fall asleep, less than half the time.
[ ] 2 I take at least 30 minutes to fall asleep, more than half the time.
[ ] 3 I take more than 60 minutes to fall asleep, more than half the time.
2. Sleep During the Night:
[ ] 0 I do not wake up at night.
[ ] 1 I have a restless, light sleep with a few brief awakenings each night.
[ ] 2 I wake up at least once a night, but I go back to sleep easily.
[ ] 3 I awaken more than once a night and stay awake for 20 minutes or more, more than half the time.
3. Waking Up Too Early:
[ ] 0 Most of the time, I awaken no more than 30 minutes before I need to get up.
[ ] 1 More than half the time, I awaken more than 30 minutes before I need to get up.
[ ] 2 I almost always awaken at least one hour or so before I need to, but I go back to sleep eventually.
[ ] 3 I awaken at least one hour before I need to, and can’t go back to sleep.
4. Sleeping Too Much:
[ ] 0 I sleep no longer than 7-8 hours/night, without napping during the day.
[ ] 1 I sleep no longer than 10 hours in a 24-hour period including naps.
[ ] 2 I sleep no longer than 12 hours in a 24-hour period including naps.
[ ] 3 I sleep longer than 12 hours in a 24-hour period including naps.
Enter the highest score on any 1 of the 4 sleep items (1-4 above) ____
5. Feeling Sad:
[ ] 0 I do not feel sad.
[ ] 1 I feel sad less than half the time.
[ ] 2 I feel sad more than half the time.
[ ] 3 I feel sad nearly all of the time.
6. Decreased Appetite:
[ ] 0 There is no change in my usual appetite.
[ ] 1 I eat somewhat less often or lesser amounts of food than usual.
[ ] 2 I eat much less than usual and only with personal effort.
[ ] 3 I rarely eat within a 24-hour period, and only with extreme personal effort or when others persuade me to eat.
7. Increased Appetite:
[ ] 0 There is no change from my usual appetite.
[ ] 1 I feel a need to eat more frequently than usual.
[ ] 2 I regularly eat more often and/or greater amounts of food than usual.
[ ] 3 I feel driven to overeat both at mealtime and between meals.
8. Decreased Weight (Within the Last Two Weeks):
[ ] 0 I have not had a change in my weight.
[ ] 1 I feel as if I’ve had a slight weight loss.
[ ] 2 I have lost 2 pounds or more.
[ ] 3 I have lost 5 pounds or more.
9. Increased Weight (Within the Last Two Weeks):
[ ] 0 I have not had a change in my weight.
[ ] 1 I feel as if I’ve had a slight weight gain.
[ ] 2 I have gained 2 pounds or more.
[ ] 3 I have gained 5 pounds or more.
Enter the highest score on any 1 of the 4 appetite/weight change items (6-9 above) ____
10. Concentration/Decision Making:
[ ] 0 There is no change in my usual capacity to concentrate or make decisions.
[ ] 1 I occasionally feel indecisive or find that my attention wanders.
[ ] 2 Most of the time, I struggle to focus my attention or to make decisions.
[ ] 3 I cannot concentrate well enough to read or cannot make even minor decisions.
11. View of Myself:
[ ] 0 I see myself as equally worthwhile and deserving as other people.
[ ] 1 I am more self-blaming than usual.
[ ] 2 I largely believe that I cause problems for others.
[ ] 3 I think almost constantly about major and minor defects in myself.
12. Thoughts of Death or Suicide:
[ ] 0 I do not think of suicide or death.
[ ] 1 I feel that life is empty or wonder if it’s worth living.
[ ] 2 I think of suicide or death several times a week for several minutes.
[ ] 3 I think of suicide or death several times a day in some detail, or I have made specific plans for suicide or have actually tried to take my life.
13. General Interest:
[ ] 0 There is no change from usual in how interested I am in other people or activities.
[ ] 1 I notice that I am less interested in people or activities.
[ ] 2 I find I have interest in only one or two of my formerly pursued activities.
[ ] 3 I have virtually no interest in formerly pursued activities.
14. Energy Level:
[ ] 0 There is no change in my usual level of energy.
[ ] 1 I get tired more easily than usual.
[ ] 2 I have to make a big effort to start or finish my usual daily activities (for example, shopping, homework, cooking, or going to work).
[ ] 3 I really cannot carry out most of my usual daily activities because I just don’t have the energy.
15. Feeling Slowed Down:
[ ] 0 I think, speak, and move at my usual rate of speed.
[ ] 1 I find that my thinking is slowed down or my voice sounds dull or flat.
[ ] 2 It takes me several seconds to respond to most questions and I’m sure my thinking is slowed.
[ ] 3 I am often unable to respond to questions without extreme effort.
16. Feeling Restless:
[ ] 0 I do not feel restless.
[ ] 1 I’m often fidgety, wringing my hands, or need to shift how I am sitting.
[ ] 2 I have impulses to move about and am quite restless.
[ ] 3 At times, I am unable to stay seated and need to pace around.
Enter the highest score on either of the 2 psychomotor items (15 or 16 above) ____
Total Score:____ (Range 0-27)
The total score is obtained by adding the highest score from items 1-4, the individual score for item 5 (sad mood), the highest score from items 6-9, the individual scores from items 10-14, and the highest score from items 15-16.
Please see Rush et al. (2003) for more detailed information on scoring and interpretation.
© QIDS copyright belongs to UT Southwestern Medical Center at Dallas, 2007
Protocol Name from Source:
The Quick Inventory of Depressive Symptoms (QIDS)
Personnel and Training Required
|Specialized requirements for biospecimen collection||No|
|Average time of greater than 15 minutes in an unaffected individual||No|
Mode of Administration
Adults, ages 18 and older.
When using this protocol, please inform your Institutional Review Boards of these questions and institute a plan of action for dealing with suicidal thoughts in your respondent. It may be necessary to create a separate protocol for immediate action and/or referral.
The Quick Inventory of Depressive Symptoms (QIDS) was vetted against several other dimensional measures for depression and ultimately selected because it is free, easily administered as a self-reported instrument for ages 12 and above, and captures the general symptoms of depression.
|Common Data Elements (CDE)||Adult Inventory of Depressive Symptomatology Self-Report Version Questionnaire Assessment Scale||6132720||CDE Browser|
Process and Review
Expert Review Panel 4 (ERP 4) reviewed the measures in the Neurology, Psychiatric, and Psychosocial domains.
Guidance from ERP 4 included the following:
- Added new measure
- No changes to existing protocol
Rush, A. J., Trivedi, M. H., Ibrahim, H. M., Carmody, T. J., Arnow, B., Klein, D. N., Markowitz, J. C., Ninan, P. T., Kornstein, S., Manber, R., Thase, M. E., Kocsis, J. H., & Keller, M. B. (2003). The 16-item Quick Inventory of Depressive Symptomatology (QIDS) Clinician Rating (QIDS-C) and Self-Report (QIDS-SR): A psychometric evaluation in patients with chronic major depression. Biological Psychiatry, 54, 573-583.
Trivedi, M. H., Rush, A. J., Crismon, M. L., Kashner, T. M., Toprac, M. G., Carmody, T. J., Key, T., Biggs, M. M., Shores-Wilson, K., Whitte, B., Suppes, T., Miller, A. L., Altshuler, K. Z., & Shon, S. P. (2004). Clinical results for the patient with major depressive disorder in the Texas Medication Algorithm Project. Archives of General Psychiatry, 61, 669-679.
|Variable Name||Variable ID||Variable Description||Version||dbGaP Mapping|
November 28, 2017
A self-report questionnaire to assess symptoms of major depressive disorder (MDD).
This measure can be used to rapidly assess depressive symptoms and select cases and non-cases. Depression is a common disorder that demonstrates a familial pattern and is comorbid with other psychiatric disorders, including anxiety disorder, substance use disorders, and eating disorders. Additionally, certain medical conditions-such as diabetes, stroke, and heart disease-can increase the risk of depression. Some individuals who present with major depressive episodes may have a bipolar spectrum disorder.
Psychiatric, depression, bipolar disorder