Protocol - Parkinsons Disease Screener - Questionnaire
This protocol includes one question from the Framingham Heart Study that assess whether the participant has ever been told by a doctor that her or she has Parkinson’s disease.
1. Have you been told by a doctor you have Parkinson Disease?
0[ ]= No
1[ ]= Yes
9[ ]= Unknown
The respondent is considered to be a Parkinson’s Disease case if they reply "Yes"
Protocol Name from Source
N/A - see source
Personnel and Training Required
|Specialized requirements for biospecimen collection||No|
|Average time of greater than 15 minutes in an unaffected individual||No|
Mode of Administration
Adults, ages 18 and older
This question from the Framingham Heart Study was selected because it has been used in a large US population-based study and subsequently validated as a screen for Parkinson’s Disease.
|Common Data Elements (CDE)||Physician Diagnosed Parkinson's Disease Personal Medical History Yes No Not Applicable Indicator||4035279||CDE Browser|
|Human Phenotype Ontology||Parkinsonism||HP:0001300||HPO|
Process and Review
Expert Review Panel 4 (ERP 4) reviewed the measures in the Neurology, Psychiatric, and Psychosocial domains.
Guidance from ERP 4 included the following:
- Added new protocol
- Created new data dictionary
National Heart, Lung, and Blood Institute (NHLBI), & Boston University. (2011). Framingham Heart Study, Cohort Examination 29: Medical History-Hospitalizations, ER Visits, MD Visits. Question number fw132.
Jain, S., Himali, J., Beiser, A., Ton, T.G., Kelly-Hayes, M., Biggs, M.L., Delaney, J.A., Rosano, C., Seshadri, S., & Frank, S.A. (2015). Validation of secondary data sources to identify Parkinson disease against clinical diagnostic criteria. American Journal of Epidemiology, 181(3), 185-190.
|Variable Name||Variable ID||Variable Description||dbGaP Mapping|
|PX131901000000||Have you been told by a doctor you have more||N/A|
Parkinsons Disease Screener
November 28, 2017
A questionnaire to screen for Parkinson’s disease.
This measure can be used to screen participants quickly in large, population-based cohorts for the presence of Parkinson’s disease. Parkinsonism occurs in about 0.2% of the population, and the risk increases with age. Parkinsonism can be caused by genetics, vascular disease, certain medications, and environmental contaminants such as manganese dust, carbon monoxide, or pesticides (Aminoff et al., 2005).
Neurology, Parkinsonism, Parkinson’s Disease, movement disorders,