PhenX Toolkit: Domains

Select	Protocol	ID
	Activities of Daily Living (ADLs) NA, see source	#250101
	Auditory Perception and Noise Exposure National Health and Nutrition Examination Survey Questionnaire (SP) AUDIOMETRY - AUQ Target Group: SPs 1+	#250201
	Behavioral Disturbances Neuropsychiatric Inventory-Questionnaire (NPI-Q)	#250301
	Cognitive Changes Informant Questionnaire on Cognitive Decline in the Elderly (IQCODE)	#250501
	Cystatin C Assay for Kidney Function National Health and Nutrition Examination Survey (NHANES) Questionnaire. Laboratory Procedures Manual	#250701
	Dental Issues and Difficulty Chewing Health, Aging and Body Composition Study Oral Health and Dental History Questions	#251301
	Falls Maintenance of Balance, Independent Living, Intellect, and Zest in the Elderly of Boston (MOBILIZE Boston)	#250601
	Family History of Dementia and Longevity Family History of Dementia and Longevity 2016, Section F	#250801
	Foot Pain Framingham Foot Assessment Clinical Tool	#250901
	Frailty Study of Osteoporotic Fractures (SOF) Frailty Index	#251001
	Involuntary Weight Loss Weight History	#251101
	Knee Injury and Osteoarthritis Knee injury and Osteoarthritis Outcome Score (KOOS)	#250401
	Life Space The Life Space Questionnaire	#251201
	Psychological Resilience Brief Resilience Scale (BRS)	#251401
	Smell and Taste National Health and Nutrition Examination Survey (NHANES), Taste and Smell Examination Component Manual, 2013. National Health and Nutrition Examination Survey (NHANES) Chemical Senses - Taste & Smell Questionnaire	#251501
	Urinary Incontinence Urinary History	#251601

The Geriatrics Working Group added the measures above to the PhenX Toolkit. They also identified additional measures in the PhenX Toolkit that are specifically related to research in this field. Toolkit users are encouraged to open, review and select measures in the Additional Relevant Measures folder.

Additional Relevant Protocols


	Age of Initiation of First Cigarette Use - Adult Tobacco Use Supplement to the Current Population Survey
	Alcohol - 30-Day Quantity and Frequency National Survey on Drug Use and Health, National Epidemiologic Survey on Alcohol and Related Conditions. Wave 1, Alcohol Use Disorder and Associated Disabilities Interview Schedule-IV (AUDADIS-IV)
	Alcohol - Age of First Use 2015 National Survey on Drug Use and Health (NSDUH)
	Alcohol - Lifetime Use
	Arthritis/Osteoarthritis
	Balance
	Cigarette Nicotine Dependence Fagerstrom Test for Nicotine Dependence
	Cigarette Smoking Status - Adolescent Population Assessment of Tobacco and Health (PATH) Study Wave 3
	Cigarette Smoking Status - Adult Population Assessment of Tobacco and Health (PATH)
	Clinician-Administered Psychiatric Assessment Structured Clinical Interview for DSM-5 (SCID-5)
	Complete Blood Count (CBC)
	Current Environmental Tobacco Smoke Exposure National Health and Nutrition Examination Survey (NHANES), 2007-2008 Family Questionnaire
	Exercise Capacity/Six-Minute Walk Test Six-Minute Walk Test (6MWT)
	Fracture History
	Global Mental Status Screener - Adult Montreal Cognitive Assessment (MOCA©)
	Global Mental Status Screener - Child The Ages & Stages Questionnaires®, Third Edition (ASQ-3™)
	Global Mental Status Screener - Older Children and Adolescents Children’s Global Assessment Scale (CGAS)
	Height - Knee Height 1988-1994 NHANES Body Measurements Protocol
	Height - Recumbent Length 2007 National Health and Nutrition Examination Survey (NHANES) Anthropometry Procedures Manual
	Height - Self-Reported Height 2007-2008 National Health and Nutritional Examination Survey (NHANES) Weight History Questionnaire
	Height - Standing Height 2007 National Health and Nutrition Examination Survey (NHANES) Anthropometry Procedures Manual
	History of Stroke - Ischemic Infarction and Hemorrhage Jackson Heart Study (JHS)
	Male Sexual Function Study for Future Families and International Index of Erectile Function (IIEF)
	Muscle Strength 2013-2014 National Health and Nutrition Examination Survey Muscle Strength Procedures Manual
	Neuropathy - Autonomic Assessment - Adult Survey of Autonomic Symptoms (SAS)
	Neuropathy - Clinical Assessment Charcot-Marie-Tooth Neuropathy Score
	Number of Natural Teeth
	Parkinsons Disease Symptoms Movement Disorder Society United Parkinson’s Disease Rating Scale (MDS-UPDRS)
	Patterns of Substance Use - Adolescents 2015 Monitoring the Future (MTF)
	Patterns of Substance Use - Adults - Binge-Drinking National Epidemiologic Survey on Alcohol and Related Conditions-III (NESARC-III)
	Physical Functioning - Objective Short Physical Performance Battery
	Physical Functioning - Subjective 2005-2006 National Health and Nutrition Examination Survey (NHANES) Sample Person Questionnaire: Physical Functioning Module
	Physical, Social, and Mental Health Functioning (SF-36V2)
	Pulse Oximetry (Rest) World Health Organization (WHO) Pulse Oximetry Training Manual
	Quality of Life - Adult
	Quality of Life - Pediatric
	Screening and Severity of Substance Use Problems - Adolescents
	Screening and Severity of Substance Use Problems - Adults - Alcohol - Lifetime Brief Michigan Alcoholism Screening Test (Brief MAST)
	Screening and Severity of Substance Use Problems - Adults - Alcohol - Past 12 Months Alcohol Use Disorders Identification Test (AUDIT)
	Screening and Severity of Substance Use Problems - Adults - Drugs Drug Abuse Screening Test (DAST-10)
	Signs of Essential Tremor Washington Heights-Inwood Genetic Study of Essential Tremor (WHIGET) Tremor Rating Scale
	Sleep Disorders Screener
	Spine and Femur Bone Density by Dual-Energy X-ray Absorptiometry
	Substances - 30-Day Frequency 2015 National Survey on Drug Use and Health (NSDUH)
	Substances - Age of First Use 2015 National Survey on Drug Use and Health (NSDUH)
	Substances - Lifetime Use National Epidemiologic Survey on Alcohol and Related Conditions-III (NESARC-III)
	Tobacco - Age of Initiation of Use - Adolescent
	Total Physical Activity - Comprehensive - Adolescent 3-Day Physical Activity Recall
	Verbal Memory - Adult Logical Memory subtest Wechsler Memory Scale®, Fourth Edition (WMS®-IV).
	Verbal Memory - Child Verbal Memory Subscales of the Children’s Memory Scale (CMS)
	Visual Memory - Adult Visual Reproductions subtest of the Wechsler Memory Scale® Fourth Edition (WMS®-IV)
	Visual Memory - Child The Visual Memory subtest of the Children’s Memory Scale®
	Weight Loss/Gain 2007-2008 National Health and Nutrition Examination Survey (NHANES) Weight History Questionnaire
	Working Memory - Adult Digit Span Subtest of the Wechsler Adult Intelligence Scale®, Fourth Edition (WAIS®-IV).
	Working Memory - Child Attention and Concentration Subtests of the Children’s Memory Scale (CMS)

Release Date:

July 2, 2018; reviewed July 2, 2018

Scope of Domain:

Scope Elements	Final Measures To Toolkit
Arthritis/Chronic Inflammation	Knee Injury and Osteoarthritis
Dementia (Parkinson’s disease dementia, lewy body dementia, vascular dementia), Alzheimer’s	Behavioral Disturbances Cognitive Changes
Depression/Anxiety	Depression Symptoms (added two protocols to existing measure)
Falls	Falls
Family health history (Longevity)	Family History of Dementia and Longevity
Foot Disorders	Foot Pain
Frailty	Frailty
Involuntary Weight Loss/BMI Change	Involuntary Weight Loss
Kidney	Cystatin C Assay for Kidney Function
Life Space	Life Space
Oral and dental care (tooth decay, gum disease)	Dental Issues and Difficulty Chewing
Physical Functioning	400 Meter Walk
Resilience	Resilience
Sensory capabilities/Impairment	Auditory Perception and Noise Exposure Smell and Taste
Urinary issues	Urinary Incontinence
Sexuality	Addressed elsewhere in PhenX Toolkit
Sleep	Addressed elsewhere in PhenX Toolkit
Verbal Memory	Addressed elsewhere in PhenX Toolkit

Working Group Roster:

WG Members:

Mary Sano, PhD, Chair Icahn School of Medicine New York, NY	Steven Cummings, MD California Pacific Medical Center San Francisco, CA
Philip De Jager, MD, PhD, MMSc Columbia University New York, NY	Colin Depp, PhD University of California, San Diego San Diego, CA
Jack Guralnik, MD, PhD, MPH University of Maryland, Baltimore Baltimore, MD	Tamara Harris, MD National Institute on Aging (NIA) Bethesda, MS
Denise Houston, PhD Wake Forest University Winston-Salem, NC	Claudia Kawas, MD University of California, Irvine Irvine, CA
Douglas P. Kiel, MD Harvard University Belmont, MA	Richard Mayeux, MD, MSc Columbia University New York, NY

SC Liaison, WG Manager and WG Supervisor:

Lindsay A. Farrer, PhD, SC Liaison Boston University Boston, MA	Lisa Kilpatrick, MS, WG Manager RTI International Atlanta, GA
Michael Phillips, MS, WG Supervisor RTI International Research Triangle Park, NC

Geriatrics Supplemental Information includes:

There is no supplemental information for this domain.

Additional Information for Geriatrics Measures:

There is no additional information for this domain.

Protocol Name	Status	DCW	DD	DD Mapping

Research Domain - Geriatrics

Research Domains:

Activities of Daily Living (ADLs) NA, see source

#250101

Auditory Perception and Noise Exposure National Health and Nutrition Examination Survey Questionnaire (SP) AUDIOMETRY - AUQ Target Group: SPs 1+

#250201

Behavioral Disturbances Neuropsychiatric Inventory-Questionnaire (NPI-Q)

#250301

Cognitive Changes Informant Questionnaire on Cognitive Decline in the Elderly (IQCODE)

#250501

Cystatin C Assay for Kidney Function National Health and Nutrition Examination Survey (NHANES) Questionnaire. Laboratory Procedures Manual

#250701

Dental Issues and Difficulty Chewing Health, Aging and Body Composition Study Oral Health and Dental History Questions

#251301

Falls Maintenance of Balance, Independent Living, Intellect, and Zest in the Elderly of Boston (MOBILIZE Boston)

#250601

Family History of Dementia and Longevity Family History of Dementia and Longevity 2016, Section F

#250801

Foot Pain Framingham Foot Assessment Clinical Tool

#250901

Frailty Study of Osteoporotic Fractures (SOF) Frailty Index

#251001

Involuntary Weight Loss Weight History

#251101

Knee Injury and Osteoarthritis Knee injury and Osteoarthritis Outcome Score (KOOS)

#250401

Life Space The Life Space Questionnaire

#251201

Psychological Resilience Brief Resilience Scale (BRS)

#251401

Smell and Taste National Health and Nutrition Examination Survey (NHANES), Taste and Smell Examination Component Manual, 2013. National Health and Nutrition Examination Survey (NHANES) Chemical Senses - Taste & Smell Questionnaire

#251501

Urinary Incontinence Urinary History

#251601

Age of Initiation of First Cigarette Use - Adult Tobacco Use Supplement to the Current Population Survey

Alcohol - 30-Day Quantity and Frequency National Survey on Drug Use and Health, National Epidemiologic Survey on Alcohol and Related Conditions. Wave 1, Alcohol Use Disorder and Associated Disabilities Interview Schedule-IV (AUDADIS-IV)

Alcohol - Age of First Use 2015 National Survey on Drug Use and Health (NSDUH)

Cigarette Nicotine Dependence Fagerstrom Test for Nicotine Dependence

Cigarette Smoking Status - Adolescent Population Assessment of Tobacco and Health (PATH) Study Wave 3

Cigarette Smoking Status - Adult Population Assessment of Tobacco and Health (PATH)

Clinician-Administered Psychiatric Assessment Structured Clinical Interview for DSM-5 (SCID-5)

Current Environmental Tobacco Smoke Exposure National Health and Nutrition Examination Survey (NHANES), 2007-2008 Family Questionnaire

Exercise Capacity/Six-Minute Walk Test Six-Minute Walk Test (6MWT)

Global Mental Status Screener - Adult Montreal Cognitive Assessment (MOCA©)

Global Mental Status Screener - Child The Ages & Stages Questionnaires®, Third Edition (ASQ-3™)

Global Mental Status Screener - Older Children and Adolescents Children’s Global Assessment Scale (CGAS)

Height - Knee Height 1988-1994 NHANES Body Measurements Protocol

Height - Recumbent Length 2007 National Health and Nutrition Examination Survey (NHANES) Anthropometry Procedures Manual

Height - Self-Reported Height 2007-2008 National Health and Nutritional Examination Survey (NHANES) Weight History Questionnaire

Height - Standing Height 2007 National Health and Nutrition Examination Survey (NHANES) Anthropometry Procedures Manual

History of Stroke - Ischemic Infarction and Hemorrhage Jackson Heart Study (JHS)

Male Sexual Function Study for Future Families and International Index of Erectile Function (IIEF)

Muscle Strength 2013-2014 National Health and Nutrition Examination Survey Muscle Strength Procedures Manual

Neuropathy - Autonomic Assessment - Adult Survey of Autonomic Symptoms (SAS)

Neuropathy - Clinical Assessment Charcot-Marie-Tooth Neuropathy Score

Parkinsons Disease Symptoms Movement Disorder Society United Parkinson’s Disease Rating Scale (MDS-UPDRS)

Patterns of Substance Use - Adolescents 2015 Monitoring the Future (MTF)

Patterns of Substance Use - Adults - Binge-Drinking National Epidemiologic Survey on Alcohol and Related Conditions-III (NESARC-III)

Physical Functioning - Objective Short Physical Performance Battery

Physical Functioning - Subjective 2005-2006 National Health and Nutrition Examination Survey (NHANES) Sample Person Questionnaire: Physical Functioning Module

Pulse Oximetry (Rest) World Health Organization (WHO) Pulse Oximetry Training Manual

Screening and Severity of Substance Use Problems - Adults - Alcohol - Lifetime Brief Michigan Alcoholism Screening Test (Brief MAST)

Screening and Severity of Substance Use Problems - Adults - Alcohol - Past 12 Months Alcohol Use Disorders Identification Test (AUDIT)

Screening and Severity of Substance Use Problems - Adults - Drugs Drug Abuse Screening Test (DAST-10)

Signs of Essential Tremor Washington Heights-Inwood Genetic Study of Essential Tremor (WHIGET) Tremor Rating Scale

Substances - 30-Day Frequency 2015 National Survey on Drug Use and Health (NSDUH)

Substances - Age of First Use 2015 National Survey on Drug Use and Health (NSDUH)

Substances - Lifetime Use National Epidemiologic Survey on Alcohol and Related Conditions-III (NESARC-III)

Total Physical Activity - Comprehensive - Adolescent 3-Day Physical Activity Recall

Verbal Memory - Adult Logical Memory subtest Wechsler Memory Scale®, Fourth Edition (WMS®-IV).

Verbal Memory - Child Verbal Memory Subscales of the Children’s Memory Scale (CMS)

Visual Memory - Adult Visual Reproductions subtest of the Wechsler Memory Scale® Fourth Edition (WMS®-IV)

Visual Memory - Child The Visual Memory subtest of the Children’s Memory Scale®

Weight Loss/Gain 2007-2008 National Health and Nutrition Examination Survey (NHANES) Weight History Questionnaire

Working Memory - Adult Digit Span Subtest of the Wechsler Adult Intelligence Scale®, Fourth Edition (WAIS®-IV).

Working Memory - Child Attention and Concentration Subtests of the Children’s Memory Scale (CMS)

Release Date:

Scope of Domain:

Working Group Roster:

Geriatrics Supplemental Information includes:

Activities of Daily Living (ADLs)
NA, see source

Auditory Perception and Noise Exposure
National Health and Nutrition Examination Survey Questionnaire (SP) AUDIOMETRY - AUQ Target Group: SPs 1+

Behavioral Disturbances
Neuropsychiatric Inventory-Questionnaire (NPI-Q)

Cognitive Changes
Informant Questionnaire on Cognitive Decline in the Elderly (IQCODE)

Cystatin C Assay for Kidney Function
National Health and Nutrition Examination Survey (NHANES) Questionnaire. Laboratory Procedures Manual

Dental Issues and Difficulty Chewing
Health, Aging and Body Composition Study Oral Health and Dental History Questions

Falls
Maintenance of Balance, Independent Living, Intellect, and Zest in the Elderly of Boston (MOBILIZE Boston)

Family History of Dementia and Longevity
Family History of Dementia and Longevity 2016, Section F

Foot Pain
Framingham Foot Assessment Clinical Tool

Frailty
Study of Osteoporotic Fractures (SOF) Frailty Index

Involuntary Weight Loss
Weight History

Knee Injury and Osteoarthritis
Knee injury and Osteoarthritis Outcome Score (KOOS)

Life Space
The Life Space Questionnaire

Psychological Resilience
Brief Resilience Scale (BRS)

Smell and Taste
National Health and Nutrition Examination Survey (NHANES), Taste and Smell Examination Component Manual, 2013. National Health and Nutrition Examination Survey (NHANES) Chemical Senses - Taste & Smell Questionnaire

Urinary Incontinence
Urinary History

Age of Initiation of First Cigarette Use - Adult

Tobacco Use Supplement to the Current Population Survey

Alcohol - 30-Day Quantity and Frequency

National Survey on Drug Use and Health, National Epidemiologic Survey on Alcohol and Related Conditions. Wave 1, Alcohol Use Disorder and Associated Disabilities Interview Schedule-IV (AUDADIS-IV)

Alcohol - Age of First Use

2015 National Survey on Drug Use and Health (NSDUH)

Cigarette Nicotine Dependence

Fagerstrom Test for Nicotine Dependence

Cigarette Smoking Status - Adolescent

Population Assessment of Tobacco and Health (PATH) Study Wave 3

Cigarette Smoking Status - Adult

Population Assessment of Tobacco and Health (PATH)

Clinician-Administered Psychiatric Assessment

Structured Clinical Interview for DSM-5 (SCID-5)

Current Environmental Tobacco Smoke Exposure

National Health and Nutrition Examination Survey (NHANES), 2007-2008 Family Questionnaire

Exercise Capacity/Six-Minute Walk Test

Six-Minute Walk Test (6MWT)

Global Mental Status Screener - Adult

Montreal Cognitive Assessment (MOCA©)

Global Mental Status Screener - Child

The Ages & Stages Questionnaires®, Third Edition (ASQ-3™)

Global Mental Status Screener - Older Children and Adolescents

Children’s Global Assessment Scale (CGAS)

Height - Knee Height

1988-1994 NHANES Body Measurements Protocol

Height - Recumbent Length

2007 National Health and Nutrition Examination Survey (NHANES) Anthropometry Procedures Manual

Height - Self-Reported Height

2007-2008 National Health and Nutritional Examination Survey (NHANES) Weight History Questionnaire

Height - Standing Height

2007 National Health and Nutrition Examination Survey (NHANES) Anthropometry Procedures Manual

History of Stroke - Ischemic Infarction and Hemorrhage

Jackson Heart Study (JHS)

Male Sexual Function

Study for Future Families and International Index of Erectile Function (IIEF)

Muscle Strength

2013-2014 National Health and Nutrition Examination Survey Muscle Strength Procedures Manual

Neuropathy - Autonomic Assessment - Adult

Survey of Autonomic Symptoms (SAS)

Neuropathy - Clinical Assessment

Charcot-Marie-Tooth Neuropathy Score

Parkinsons Disease Symptoms

Movement Disorder Society United Parkinson’s Disease Rating Scale (MDS-UPDRS)

Patterns of Substance Use - Adolescents

2015 Monitoring the Future (MTF)

Patterns of Substance Use - Adults - Binge-Drinking

National Epidemiologic Survey on Alcohol and Related Conditions-III (NESARC-III)

Physical Functioning - Objective

Short Physical Performance Battery

Physical Functioning - Subjective

2005-2006 National Health and Nutrition Examination Survey (NHANES) Sample Person Questionnaire: Physical Functioning Module

Pulse Oximetry (Rest)

World Health Organization (WHO) Pulse Oximetry Training Manual

Screening and Severity of Substance Use Problems - Adults - Alcohol - Lifetime

Brief Michigan Alcoholism Screening Test (Brief MAST)

Screening and Severity of Substance Use Problems - Adults - Alcohol - Past 12 Months

Alcohol Use Disorders Identification Test (AUDIT)

Screening and Severity of Substance Use Problems - Adults - Drugs

Drug Abuse Screening Test (DAST-10)

Signs of Essential Tremor

Washington Heights-Inwood Genetic Study of Essential Tremor (WHIGET) Tremor Rating Scale

Substances - 30-Day Frequency

2015 National Survey on Drug Use and Health (NSDUH)

Substances - Age of First Use

2015 National Survey on Drug Use and Health (NSDUH)

Substances - Lifetime Use

National Epidemiologic Survey on Alcohol and Related Conditions-III (NESARC-III)

Total Physical Activity - Comprehensive - Adolescent

3-Day Physical Activity Recall

Verbal Memory - Adult

Logical Memory subtest Wechsler Memory Scale®, Fourth Edition (WMS®-IV).

Verbal Memory - Child

Verbal Memory Subscales of the Children’s Memory Scale (CMS)

Visual Memory - Adult

Visual Reproductions subtest of the Wechsler Memory Scale® Fourth Edition (WMS®-IV)

Visual Memory - Child

The Visual Memory subtest of the Children’s Memory Scale®

Weight Loss/Gain

2007-2008 National Health and Nutrition Examination Survey (NHANES) Weight History Questionnaire

Working Memory - Adult

Digit Span Subtest of the Wechsler Adult Intelligence Scale®, Fourth Edition (WAIS®-IV).

Working Memory - Child

Attention and Concentration Subtests of the Children’s Memory Scale (CMS)