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Protocol - Alcohol - Lifetime Use Disorder

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Description:

Measurement of respondent’s symptoms of alcohol use disorder. These responses correspond with criteria from the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5).

Protocol:

1a. Now I’m going to ask you about some experiences you may have had with your drinking. As I read each experience, please tell me if this has ever happened to you.

In your entire life did you EVER…(PAUSE)

(Repeat phrase frequently)

b. Did this happen in the last 12 months?

c. Did this happen before 12 months ago, that is before last (Month one year ago?)

d.

(1) Find that your usual number of drinks had much less effect on you than it once did?

1 [ ] Yes

2 [ ] No - Go to next experience

1 [ ] Yes

2 [ ] No - Mark "Yes" in column c

1 [ ] Yes - Mark Box B1

2 [ ] No - Go to next experience

B1 (For Q1-Q4)

1 [ ] Had to drink much more to get an effect or drank the equivalent of a fifth of liquor

(2) Find that you had to drink much more than you once did to get the effect you wanted?

1 [ ] Yes

2 [ ] No - Go to next experience

1 [ ] Yes

2 [ ] No - Mark "Yes" in column c

1 [ ] Yes - Mark Box B1

2 [ ] No - Go to next experience

(3) Drink as much as a fifth of liquor in one day, that would be about 20 drinks, or 3 bottles of wine, or as much as 3 six-packs of beer in a single day?

1 [ ] Yes

2 [ ] No - Go to next experience

1 [ ] Yes

2 [ ] No - Mark "Yes" in column c

1 [ ] Yes - Mark Box B1

2 [ ] No - Go to next experience

(4) Increase your drinking because the amount you used to drink didn’t give you the same effect anymore?

1 [ ] Yes

2 [ ] No - Go to next experience

1 [ ] Yes

2 [ ] No - Mark "Yes" in column c

1 [ ] Yes - Mark Box B1

2 [ ] No - Go to next experience

(5) More than once WANT to stop or cut down on your drinking?

1 [ ] Yes

2 [ ] No - Go to next experience

1 [ ] Yes

2 [ ] No - Mark "Yes" in column c

1 [ ] Yes - Mark Box B1

2 [ ] No - Go to next experience

B2 (For Q5-Q6)

1 [ ] Wanted or tried to stop or cut down on your drinking

(6) More than once TRY to stop or cut down on your drinking but found you couldn’t do it?

1 [ ] Yes

2 [ ] No - Go to next experience

1 [ ] Yes

2 [ ] No - Mark "Yes" in column c

1 [ ] Yes - Mark Box B1

2 [ ] No - Go to next experience

(7) Have a period when you ended up drinking more than you meant to?

1 [ ] Yes

2 [ ] No - Go to next experience

1 [ ] Yes

2 [ ] No - Mark "Yes" in column c

1 [ ] Yes - Mark Box B1

2 [ ] No - Go to next experience

B3 (For Q7-Q8)

1 [ ] Drink more or longer than you meant to

(8) Have a period when you kept on drinking for longer than you had intended to?

1 [ ] Yes

2 [ ] No - Go to next experience

1 [ ] Yes

2 [ ] No - Mark "Yes" in column c

1 [ ] Yes - Mark Box B1

2 [ ] No - Go to next experience

The next few questions are about the bad aftereffects of drinking that people may have when the effects of alcohol are wearing off. This includes the morning after drinking or in the first few days after stopping or cutting down. Did you EVER…

(9) Have trouble falling asleep or staying asleep (when the effects of alcohol were wearing off)?

1 [ ] Yes

2 [ ] No - Go to next experience

1 [ ] Yes

2 [ ] No - Mark "Yes" in column c

1 [ ] Yes - Go to next experience

2 [ ] No - Go to next experience

For Q9-Q16

(10) Find yourself shaking or your hands trembling?

1 [ ] Yes

2 [ ] No - Go to next experience

1 [ ] Yes

2 [ ] No - Mark "Yes" in column c

1 [ ] Yes - Go to next experience

2 [ ] No - Go to next experience

(11) Feel anxious or nervous?

1 [ ] Yes

2 [ ] No - Go to next experience

1 [ ] Yes

2 [ ] No - Mark "Yes" in column c

1 [ ] Yes - Go to next experience

2 [ ] No - Go to next experience

(12) Feel sick to your stomach or vomit (when the effects of alcohol were wearing off)?

1 [ ] Yes

2 [ ] No - Go to next experience

1 [ ] Yes

2 [ ] No - Mark "Yes" in column c

1 [ ] Yes - Go to next experience

2 [ ] No - Go to next experience

(13) Feel more restless than is usual for you?

1 [ ] Yes

2 [ ] No - Go to next experience

1 [ ] Yes

2 [ ] No - Mark "Yes" in column c

1 [ ] Yes - Go to next experience

2 [ ] No - Go to next experience

(14) Find yourself sweating or your heart beating fast?

1 [ ] Yes

2 [ ] No - Go to next experience

1 [ ] Yes

2 [ ] No - Mark "Yes" in column c

1 [ ] Yes - Go to next experience

2 [ ] No - Go to next experience

(15) See, feel, or hear things that weren’t really there (when the effects of alcohol were wearing off)?

1 [ ] Yes

2 [ ] No - Go to next experience

1 [ ] Yes

2 [ ] No - Mark "Yes" in column c

1 [ ] Yes - Go to next experience

2 [ ] No - Go to next experience

(16) Have fits or seizures?

1 [ ] Yes

2 [ ] No - Go to next experience

1 [ ] Yes

2 [ ] No - Mark "Yes" in column c

1 [ ] Yes - Go to next experience

2 [ ] No - Go to next experience

Check Item 2.11

Are at least 2 items marked "Yes" in column b, items 9-16

1 [ ] Yes

2 [ ] No - SKIP to Check Item 2.12

(17) You just mentioned that you had SOME bad aftereffects when stopping or cutting down on drinking in the last 12 months. Did at least 2 of these experiences happen around the same time DURING the last 12 months?

1 [ ] Yes

2 [ ] No

Check Item 2.12

Are at least 2 items marked "Yes" in column c, items 9-16?

1 [ ] Yes

2 [ ] No - SKIP to (19)

(18) You (also/just) mentioned that you had SOME bad aftereffects when stopping or cutting down on drinking before 12 months ago. Did at least 2 of these experiences happen around the same time BEFORE 12 months ago?

1a. In your entire life did you EVER…(PAUSE)

(Repeat phrase frequently)

b. Did this happen in the last 12 months?

c. Did this happen before 12 months ago, that is before last (Month one year ago)?

(19) Take a drink or use any drug or medicine, other than aspirin, Advil or Tylenol, to GET OVER any of the bad aftereffects of drinking?

1 [ ] Yes

2 [ ] No - Go to next experience

1 [ ] Yes

2 [ ] No - Mark "Yes" in column c

1 [ ] Yes - Mark Box B4-2

2 [ ] No

B4-2 (For Q19-Q20)

1 [ ] Took a drink, medicine or drug to get over or avoid the bad aftereffects of drinking

(20) Take a drink or use any drug or medicine, other than aspirin, Advil or Tylenol, to KEEP FROM having any of these bad aftereffects of drinking?

1 [ ] Yes

2 [ ] No - Go to next experience

1 [ ] Yes

2 [ ] No - Mark "Yes" in column c

1 [ ] Yes - Mark Box B4-2

2 [ ] No

(21) Have a period when you spent a lot of time drinking?

1 [ ] Yes

2 [ ] No - Go to next experience

1 [ ] Yes

2 [ ] No - Mark "Yes" in column c

1 [ ] Yes - Mark Box B5

2 [ ] No

B5 (For Q21-Q22)

1 [ ] Spent a lot of time drinking or getting over being sick from drinking

(22) Have a period when you spent a lot of time being sick or getting over the bad aftereffects of drinking?

1 [ ] Yes

2 [ ] No - Go to next experience

1 [ ] Yes

2 [ ] No - Mark "Yes" in column c

1 [ ] Yes - Mark Box B5

2 [ ] No

(23) Give up or cut down on activities that were important to you in order to drink-like work, school, or associating with friends or relatives?

1 [ ] Yes

2 [ ] No - Go to next experience

1 [ ] Yes

2 [ ] No - Mark "Yes" in column c

1 [ ] Yes - Mark Box B6

2 [ ] No

B6 (For Q23-24)

1 [ ] Gave up or cut down on activities that were important to you in order to drink

(24) Give up or cut down on activities that you were interested in or that gave you pleasure in order to drink?

1 [ ] Yes

2 [ ] No - Go to next experience

1 [ ] Yes

2 [ ] No - Mark "Yes" in column c

1 [ ] Yes - Mark Box B6

2 [ ] No

(25) Continue to drink even though you knew it was making you feel depressed, uninterested in things, or suspicious or distrustful of other people?

1 [ ] Yes

2 [ ] No - Go to next experience

1 [ ] Yes

2 [ ] No - Mark "Yes" in column c

1 [ ] Yes - Mark Box B7

2 [ ] No

B7 (For Q25-Q27)

1 [ ] Drank even though it affected your mood or health

(26) Continue to drink even though you knew it was causing you a health problem or making a health problem worse?

1 [ ] Yes

2 [ ] No - Go to next experience

1 [ ] Yes

2 [ ] No - Mark "Yes" in column c

1 [ ] Yes - Mark Box B7

2 [ ] No

(27) Continue to drink even though you had experienced a prior blackout, that is, awakened the next day not being able to remember some of the things you did while drinking or after drinking?

1 [ ] Yes

2 [ ] No - Go to next experience

1 [ ] Yes

2 [ ] No - Mark "Yes" in column c

1 [ ] Yes - Mark Box B7

2 [ ] No

(28) Feel a very strong urge or desire to drink?

1 [ ] Yes

2 [ ] No - Go to next experience

1 [ ] Yes

2 [ ] No - Mark "Yes" in column c

1 [ ] Yes - Mark Box B8

2 [ ] No

B8 (For Q28-Q29)

1 [ ] Had a strong desire or urge to drink

(29) Want a drink so badly that you couldn’t think of anything else?

1 [ ] Yes

2 [ ] No - Go to next experience

1 [ ] Yes

2 [ ] No - Mark "Yes" in column c

1 [ ] Yes - Mark Box B8

2 [ ] No

1a. In your entire life did you EVER…(PAUSE)

(Repeat phrase frequently)

b. Did this happen in the last 12 months?

c. Did this happen before 12 months ago, that is before last (Month one year ago)?

d.

(30) Have a period when your drinking or being sick from drinking often interfered with taking care of your home or family?

1 [ ] Yes

2 [ ] No - Go to next experience

1 [ ] Yes

2 [ ] No - Mark "Yes" in column c

1 [ ] Yes - Mark Box B9

2 [ ] No

B9 (For Q30-Q32)

1 [ ] Were drunk or hung over when you were supposed to be doing something important

(31) Have job or school troubles because of your drinking or being sick from drinking-like missing too much work, not doing your work well, being demoted or losing a job, or being suspended, expelled, or dropping out of school?

1 [ ] Yes

2 [ ] No - Go to next experience

1 [ ] Yes

2 [ ] No - Mark "Yes" in column c

1 [ ] Yes - Mark Box B9

2 [ ] No

(32) Continue to drink even though it was causing you problems at school or at work?

1 [ ] Yes

2 [ ] No - Go to next experience

1 [ ] Yes

2 [ ] No - Mark "Yes" in column c

1 [ ] Yes - Mark Box B9

2 [ ] No

(33) More than once drive a car or other vehicle WHILE you were drinking?

1 [ ] Yes

2 [ ] No - Go to next experience

1 [ ] Yes

2 [ ] No - Mark "Yes" in column c

1 [ ] Yes - Mark Box B10

2 [ ] No

B10 (For Q33-Q36)

1 [ ] Were in a situation while drinking or after drinking where you could have been hurt

(34) Drive a car, motorcycle, truck, boat or other vehicle and have an accident WHILE you were under the influence of alcohol?

1 [ ] Yes

2 [ ] No - Go to next experience

1 [ ] Yes

2 [ ] No - Mark "Yes" in column c

1 [ ] Yes - Mark Box B10

2 [ ] No

(35) More than once drive a car, motorcycle, truck, boat, or other vehicle AFTER having too much to drink?

1 [ ] Yes

2 [ ] No - Go to next experience

1 [ ] Yes

2 [ ] No - Mark "Yes" in column c

1 [ ] Yes - Mark Box B10

2 [ ] No

(36) Get into situations while drinking or after drinking that increased your chances of getting hurt-like swimming, using machinery, or walking in a dangerous area or around heavy traffic?

1 [ ] Yes

2 [ ] No - Go to next experience

1 [ ] Yes

2 [ ] No - Mark "Yes" in column c

1 [ ] Yes - Mark Box B10

2 [ ] No

(37) Have arguments or problems with your spouse or partner or family or friends because of your drinking?

1 [ ] Yes

2 [ ] No - Go to next experience

1 [ ] Yes

2 [ ] No - Mark "Yes" in column c

1 [ ] Yes - Mark Box B11

2 [ ] No

B11 (For Q37-Q39)

1 [ ] Drank even though it affected your relationships with other people

(38) Continue to drink even though it was causing you trouble with your family or friends?

1 [ ] Yes

2 [ ] No - Go to next experience

1 [ ] Yes

2 [ ] No - Mark "Yes" in column c

1 [ ] Yes - Mark Box B11

2 [ ] No

(39) Get into physical fights while drinking or right after drinking?

1 [ ] Yes

2 [ ] No - Go to Check Item 2.14

1 [ ] Yes

2 [ ] No - Mark "Yes" in column c

1 [ ] Yes - Mark Box B11

2 [ ] No

Check Item 2.14

Are there AT LEAST 2 BOXES marked "Yes" for Boxes 1-3, (4-1 or 4-2), 5-11 in 1, column d?

1 [ ] Yes

2 [ ] No - SKIP to 3a2

2a. You mentioned that before 12 months ago, you(Read ALL summary statements marked in Boxes B1, B2, B3, B4-1, B4-2, B5-B12 in 1, column d).

Before last (Month one year ago), was there EVER a period when SOME of these experiences were happening around the same time ON AND OFF FOR A FEW MONTHS OR LONGER?

1 [ ] Yes - SKIP to 2d

2 [ ] No

b. Before last (Month one year ago), was there EVER a period when SOME of these experiences were happening around the same time MOST DAYS FOR AT LEAST A MONTH?

1 [ ] Yes - SKIP to 2d

2 [ ] No

c. Before last (Month one year ago), was there EVER a time when SOME of these experiences happened within the same 1-year period?

1 [ ] Yes

2 [ ] No - SKIP to 3a2

d. About how old were you the FIRST time SOME of these experiences BEGAN to happen around the same time?

______ Age

e. In your ENTIRE LIFE, how many separate periods like this did you have when SOME of these experiences were happening around the same time?

By separate periods, I mean times that were separated by at least 1 year when you EITHER STOPPED drinking entirely (PAUSE) OR you didn’t have any of the experiences you mentioned with alcohol at all.

______ Number

Check Item 2.15

Is number entered in 2e, 2 or more or unknown?

1 [ ] Yes

2 [ ] No - SKIP to 2h

2f. What was the LONGEST period you had when SOME of these experiences were happening around the same time?

______ Month(s)

OR

______ Year(s)

g. How old were you the MOST RECENT time SOME of these experiences BEGAN to happen around the same time?

______ Age - SKIP to Check Item 2.16

h. How long did this period last when SOME of these experiences were happening around the same time?

______ Month(s)

OR

______ Year(s)

Check Item 2.16

Is at least 1 item marked in 1b, items (1)-(16), (19)-(27), or (30)-(39)?

1 [ ] Yes - SKIP to 3a2

2 [ ] No

2i. About how old were you when you FINALLY STOPPED having these experiences with alcohol? By finally stopped, I mean they never started happening again.

______ Age

3a. In your ENTIRE LIFE, did you EVER…(PAUSE)

(Repeat phrase frequently)

b. Did this happen in the last 12 months?

c. Did this happen before 12 months ago, that is, before last (Month one year ago)?

(2) Ride in a car as a passenger while you were drinking?

1 [ ] Yes

2 [ ] No - Go to next experience

1 [ ] Yes

2 [ ] No - Mark "Yes" in column c

1 [ ] Yes

2 [ ] No

(3) Drive a car, motorcycle, truck, or other vehicle and injure yourself or someone else in an accident while you were under the influence of alcohol?

1 [ ] Yes

2 [ ] No - Go to next experience

1 [ ] Yes

2 [ ] No - Mark "Yes" in column c

1 [ ] Yes

2 [ ] No

(4) Accidentally injure yourself or someone else in any way other than motor vehicle accidents, like a bad fall or bad cut, while you were under the influence of alcohol?

1 [ ] Yes

2 [ ] No - Go to next experience

1 [ ] Yes

2 [ ] No - Mark "Yes" in column c

1 [ ] Yes

2 [ ] No

(5) More than once get arrested, held at a police station, or have any other legal problems because of your drinking?

1 [ ] Yes

2 [ ] No - Go to next experience

1 [ ] Yes

2 [ ] No - Mark "Yes" in column c

1 [ ] Yes

2 [ ] No

(6) Ride in a car or other vehicle WHILE the driver was drinking?

1 [ ] Yes

2 [ ] No - Go to Check Item 2.16A

1 [ ] Yes

2 [ ] No - Mark "Yes" in column c

1 [ ] Yes

2 [ ] No

Check Item 2.16A

Does Check Item 2.4A = 1 (did respondent ever drink at least 12 drinks in any year or 5+ drinks in a single day in any year)?

1 [ ] Yes

2 [ ] No

Protocol Name from Source:

National Epidemiologic Survey on Alcohol and Related Conditions-III (NESARC-III)

Availability:

Publicly available

Personnel and Training Required

The interviewer must be trained and found competent to conduct personal interviews with individuals from the general population. The interviewer should be trained to prompt respondents further if a "don’t know" response is provided. It is preferable either to read the questionnaire aloud to the respondent or administer it in an audio-assisted computer interview (ACASI) format. The questions are sensitive in nature, and the interviewer should be trained to react appropriately to emotional responses. If a distressed respondent protocol is adopted, the interviewer should be trained to administer those procedures.

Equipment Needs

While the Alcohol Use Disorder and Associated Disabilities Interview Schedule-5 (AUDADIS-5) instrument was developed for administration by computer; the PhenX WG acknowledges that these questions can be administered in a noncomputerized format. Hasin et al. (1997) and Grant et al. (1995) used the AUDADIS in paper-and-pencil format, while Grant et al. (2003) obtained data with the computerized format.

Requirements
Requirement CategoryRequired
Major equipment No
Specialized training No
Specialized requirements for biospecimen collection No
Average time of greater than 15 minutes in an unaffected individual No
Mode of Administration

Interviewer-administered questionnaire

Life Stage:

Adult

Participants:

Adults aged 18 years or older

Specific Instructions:

The Alcohol Use Disorder and Associated Disabilities Interview Schedule-Diagnostic and Statistical Manual of Mental Disorders-Fifth Edition Version (AUDADIS-5) Alcohol and Drug Use Disorders Scoring Algorithms are provided for data interpretation. Please click here to access the scoring algorithm document. The algorithms were constructed by Yoanna McDowell, M.A, under the supervision of Dr. Kenneth Sher (University of Missouri) in 2017 and posted here with their permission. They were verified by diagnostic variables available in the NESARC-III data set and published NESARC-III diagnostic and severity prevalence data. Users are solely responsible for the use and interpretation of the algorithms and results.

Due to the complexity of the algorithms and associated analysis, Expert Review Panel 3 recommends analysis be performed by a statistician who has experience using NESARC datasets,

The Alcohol Use Disorder and Associated Disabilities Interview Schedule-Diagnostic and Statistical Manual of Mental Disorders-Fifth Edition Version (AUDADIS-5) is a complex diagnostic instrument that likely requires expertise with SAS and the NESARC dataset in order to successfully implement scoring algorithms.

Respondents are only asked this question if they answered "yes" to the Alcohol - Lifetime Use measure.

The following questions may gather sensitive information relating to the use of substances or illegal conduct. If the information is released, it might be damaging to an individual’s employability, lead to social stigmatization, or result in other consequences. For information on obtaining a Certificate of Confidentiality, which helps researchers protect the privacy of human research participants, please go to the National Human Genome Research Institute’s Institutional Review Board website.

Selection Rationale

The National Epidemiologic Survey on Alcohol and Related Conditions-III (NESARC-III) captures "diagnostic" information via the Alcohol Use Disorder and Associated Disabilities Interview Schedule (AUDADIS-5). Therefore, the user can link diagnostic data from the NESARC directly to treatment utilization also collected from the NESARC.

Language

English

Standards
StandardNameIDSource
Common Data Elements (CDE) Alcohol Lifetime Dependence And Abuse Indicator 2820811 CDE Browser
Process and Review

The Expert Review Panel 3 (ERP3) reviewed the measures in the Alcohol, Tobacco and Other Substances domain and in the Substance Abuse and Addiction Collection.

Guidance from the ERP includes:

  • Updated protocol (same source)

Partially back-compatible (updated/similar protocol which would require some changes to the data dictionary), variable mapping between current and previous protocols can be found here (link).

Previous version in Toolkit archive.

Source

National Institute on Alcohol Abuse and Alcoholism (NIAAA). (N.d.). National Epidemiologic Survey on Alcohol and Related Conditions-III (NESARC-III). Rockville, MD: National Institutes of Health. Alcohol Use Disorder and Associated Disabilities Interview Schedule (AUDADIS-5), Section 2B - Alcohol Experiences (Questions 1a-1c, 2a-2i, 3a-3c).

General References

Grant, B. F., Dawson, D. A., Stinson, F. S., Chou, P. S., Kay, W., & Pickering, R. (2003). The Alcohol Use Disorder and Associated Disabilities Interview Schedule-IV (AUDADIS-IV): Reliability of alcohol consumption, tobacco use, family history of depression and psychiatric diagnostic modules in a general population sample. Drug and Alcohol Dependence, 71(1), 7-16.

Grant, B. F., Goldstein, R. B., Saha, T. D., Chou, S. P., Jung, J., Zhang, H., Pickering, R. P., Ruan, W. J., Smith, S. M., Huang, B., & Hasin, D. S. (2015). Epidemiology of DSM-5 alcohol use disorder: Results from the National Epidemiologic Survey on Alcohol and Related Conditions III. JAMA Psychiatry, 72(8), 757-766.

Protocol ID:

30502

Variables:
Export Variables
Variable NameVariable IDVariable DescriptionVersiondbGaP Mapping
Research Domain Information
Measure Name:

Alcohol - Lifetime Use Disorder

Release Date:

November 28, 2017

Definition

To assess alcohol use disorder, respondents are asked about their lifetime and past 12 months’ experiences with drinking alcohol.

Purpose

This measure assesses criteria for alcohol use disorder as defined in the Diagnostic and Statistical Manual of Mental Disorders, 5th Edition (DSM-5).

Keywords

Alcohol, abuse, dependence, addiction, National Epidemiologic Survey on Alcohol and Related Conditions, NESARC, National Institute on Alcohol Abuse and Alcoholism, NIAAA,substance use disorder, Alcohol, Tobacco and Other Substances, ATOS