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Protocol - Acute Subjective Responses to Substances - Retrospective - Tobacco

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Description:

This instrument uses a set of self-administered questions to assess early response to tobacco smoking, and it may also be used for marijuana smoking. Seven items inquire about pleasant and unpleasant experiences and ask respondents if they encountered various effects while smoking a tobacco cigarette for the first time. Pleasurable and unpleasant sensations are rated on a scale ranging from 1 for "none" to 4 for "intense." Pleasurable rush or buzz, relaxation, nausea, cough, and dizziness are checked "yes" or "no," depending on the respondent’s experience.

Protocol:

Please rate the extent to which these words describe your feelings the very first time you smoked a cigarette. The number 1 indicates none, and 4 represents intense.

1. While smoking your very first cigarette, did you have pleasurable sensations?

[ ] 1 None

[ ] 2

[ ] 3

[ ] 4 Intense

2. While smoking your very first cigarette, did you have unpleasant sensations?

[ ] 1 None

[ ] 2

[ ] 3

[ ] 4 Intense

Please answer yes or no to the following questions about the very first cigarette you smoked.

3. While smoking your very first cigarette, did you have a pleasurable buzz or rush?

[ ] Yes

[ ] No

4. While smoking your very first cigarette, did you feel relaxed?

[ ] Yes

[ ] No

5. While smoking your very first cigarette, did you feel dizzy?

[ ] Yes

[ ] No

6. While smoking your very first cigarette, did you have nausea?

[ ] Yes

[ ] No

7. While smoking your very first cigarette, did you cough?

[ ] Yes

[ ] No

8. Were you alone the first time you experimented with cigarettes?

[ ] Yes

[ ] No

Protocol Name from Source:

Pomerleau et al, 1998

Availability:

Publicly available

Personnel and Training Required

None

Equipment Needs

None

Requirements
Requirement CategoryRequired
Major equipment No
Specialized training No
Specialized requirements for biospecimen collection No
Average time of greater than 15 minutes in an unaffected individual No
Mode of Administration

Self-administered questionnaire

Life Stage:

Adult, Senior

Participants:

Adults aged 18 years and older

Specific Instructions:

These questions are only asked if a respondent had affirmatively answered one of the questions in the "Tobacco - Smoking Status" measure. This questionnaire provides a qualitative description of the nature of early smoking experiences, so there are no specific scoring instructions.

The Substance Abuse and Addiction Working Group acknowledges that the following questions may gather sensitive information relating to the use of substances and/or illegal conduct. If the information is released, it might be damaging to an individual’s employability, lead to social stigmatization, or lead to other consequences.

Most researchers assure confidentiality as part of their informed consent process, as required by their institutional review boards. Further assurance of confidentiality may be obtained by applying to the National Institutes of Health (NIH) for a Certificate of Confidentiality, which helps researchers protect the privacy of human research participants. The procedures for the Certificate of Confidentiality can be found at the Grants Policy website of NIH: http://grants1.nih.gov/grants/policy/coc/index.htm.

Selection Rationale

This adjective checklist has been widely adopted and validated for tobacco use. An adjective checklist is also available for marijuana, but its application is limited as compared to this adjective checklist being recommended for tobacco.

Language

English

Standards
StandardNameIDSource
Common Data Elements (CDE) Tobacco Retrospective Acute Subjective Response Assessment Description Text 3332451 CDE Browser
Derived Variables

None

Process and Review

The Expert Review Panel #3 (ERP 3) reviewed the measures in Alcohol, Tobacco and Other Substances, and Substance Abuse and Addiction domains.

Guidance from ERP 3 includes:

• No significant changes to measure

Back-compatible: NA no changes to Data Dictionary

Source

Pomerleau, O. F., Pomerleau, C. S., & Namenek, R. J. (1998). Early experiences with tobacco among women smokers, ex-smokers, and never-smokers. Addiction, 93(4), 595-599.

General References

Fergusson, D. M., Horwood, J. L., Lynskey, M. T., & Madden, P. A. (2003). Early reactions to cannabis predict later dependence. Archives of General Psychiatry, 60(10), 1033-1039.

Haberstick, B. C., Ehringer, M. A., & Lessem, J. M. (2011). Dizziness and the genetic influences on subjective experiences to initial cigarette use. Addiction, 106(2), 391-399.

Perkins, K. A., Lerman, C., Coddington, S., & Karelitz, J. L. (2008). Association of retrospective early smoking experiences with prospective sensitivity to nicotine via nasal spray in nonsmokers. Nicotine and Tobacco Research, 10(8), 1335-1345.

Protocol ID:

520201

Variables:
Export Variables
Variable NameVariable IDVariable DescriptionVersiondbGaP Mapping
PX520201_First_Cigarette_Alone PX520201080000 Were you alone the first time you experimented with cigarettes? 4 N/A
PX520201_First_Cigarette_Buzz_Or_Rush PX520201030000 While smoking your very first cigarette, did you have a pleasurable buzz or rush? 4 N/A
PX520201_First_Cigarette_Cough PX520201070000 While smoking your very first cigarette, did you cough? 4 N/A
PX520201_First_Cigarette_Feel_Dizzy PX520201050000 While smoking your very first cigarette, did you feel dizzy? 4 N/A
PX520201_First_Cigarette_Feel_Relaxed PX520201040000 While smoking your very first cigarette, did you feel relaxed? 4 N/A
PX520201_First_Cigarette_Nausea PX520201060000 While smoking your very first cigarette, did you have nausea? 4 N/A
PX520201_First_Cigarette_Pleasurable_Sensations PX520201010000 While smoking your very first cigarette, did you have pleasurable sensations? 4 N/A
PX520201_First_Cigarette_Unpleasant_Sensations PX520201020000 While smoking your very first cigarette, did you have unpleasant sensations? 4 N/A
Research Domain Information
Measure Name:

Acute Subjective Responses to Substances - Retrospective

Release Date:

February 24, 2012

Definition

Instruments used separately to assess acute subjective response to substances in the past.

Purpose

The purpose of this measure is to assess acute subjective response to substances (namely, tobacco and alcohol) in the past. Although individual researchers have designed and used their own measures to assess effects of other drugs (e.g., opiates, methamphetamine, and cocaine), at the time the measures were selected for inclusion in the Toolkit, this Working Group was unable to identify a retrospective measure for other drugs that was well-established and broadly applicable.

Keywords

Acute Subjective Response to Drugs, Adjective Checklist, Alcoholism, Buzz, Dizziness, Early Response, Level of Response, Nausea, Pass Out, Prediction, Relaxation, Rush, SAA, Self-Rating of the Effects of Alcohol, Smoking, SRE, Stumbling, Tolerance, Substance-specific Intermediate Phenotypes