Protocol - Pain Quality Descriptors (Neuropathic) - Adult
The Patient-Reported Outcomes Measurement Information System (PROMIS®) Scale v2.0 - Neuropathic Pain Quality 5a is a self-administered questionnaire for individuals aged 18 years and older, assessing 5 descriptors of neuropathic pain quality, with a recall period of the past 7 days. This protocol was validated in individuals aged 18 years and older.
Because of validation in a wide range of ages, the PhenX Working Group (WG) recommends the use of the Patient-Reported Outcomes Measurement Information System (PROMIS®) Pain Quality Descriptors protocols if the study contains a broad range of ages or if the study will be tracking the same participant(s) through age transitions from childhood to adulthood. If the study involves only adults and a broader array of pain descriptors are desirable, the PhenX WG recommends the use of the Short Form-McGill Pain Questionnaire-2 (SF-MPQ-2) protocol.
The PhenX WG recommends this PROMIS® protocol. For additional information regarding PROMIS® instruments (including scoring, validity, and interpretation), please visit: www.healthmeasures.net. For specific information about this instrument, please visit:
PROMIS® Neuropathic Pain Quality 5a
Please respond to each question or statement by marking one box per row.
In the past 7 days…
|Not at all||A little bit||Somewhat||Quite abit||Verymuch|
|Did your pain feel like pins and needles?...||[ ]1||[ ]2||[ ]3||[ ]4||[ ]5|
|Did your pain feel tingly?...||[ ]1||[ ]2||[ ]3||[ ]4||[ ]5|
|Did your pain feel stinging?...||[ ]1||[ ]2||[ ]3||[ ]4||[ ]5|
|Did your pain feel electrical?...||[ ]1||[ ]2||[ ]3||[ ]4||[ ]5|
|Did your pain feel numb?...||[ ]1||[ ]2||[ ]3||[ ]4||[ ]5|
Personnel and Training Required
|Specialized requirements for biospecimen collection||No|
|Average time of greater than 15 minutes in an unaffected individual||No|
Mode of Administration
Adults aged 18 years and older
The Patient-Reported Outcomes Measurement Information System (PROMIS®) Scale v2.0 - Neuropathic Pain Quality 5a item bank is psychometrically sound, validated, well established; has standardized scoring; and is easy to implement and interpret.
English, French, Spanish
|caDSR Common Data Elements (CDE)||PROMIS v2.0 Neuropathic Pain Quality 5a PAQUAL27r Past Week Pain Felt Like Pins and Needles Score 5 Point Scale||8042082||CDE Browser|
|caDSR Common Data Elements (CDE)||PROMIS v2.0 Neuropathic Pain Quality 5a PAQUAL14r Pain Felt Tingly Score 5 Point Scale||8042085||CDE Browser|
|caDSR Common Data Elements (CDE)||PROMIS v2.0 Neuropathic Pain Quality 5a PAQUAL21r Pain Felt Stinging Score 5 Point Scale||8042086||CDE Browser|
|caDSR Common Data Elements (CDE)||PROMIS v2.0 Neuropathic Pain Quality 5a PAQUAL31r Past Week Pain Felt Electrical Score 5 Point Scale||8042087||CDE Browser|
|caDSR Common Data Elements (CDE)||PROMIS v2.0 Neuropathic Pain Quality 5a PAQUAL11r Past Week Pain Felt Numb Score 5 Point Scale||8042088||CDE Browser|
Process and Review
Protocol Name from Source
Patient-Reported Outcomes Measurement Information System (PROMIS®) Scale v2.0 - Neuropathic Pain Quality 5a
Askew, R. L., Cook, K. F., Keefe, F. J., Nowinski, C. J., Cella, D., Revicki, D. A., Morgan DeWitt, E. M., Michaud, K., Trence, D. L., & Amtmann, D. (2016). A PROMIS measure of neuropathic pain quality. Value in Health, 19(5), 623–630.
Curtis, S. A., Brandow, A. M., DeVeaux, M., Zeltermam, D., Devine, L., & Roberts, J. D. (2020). Daily cannabis users with sickle cell disease show fewer admissions than others with similar pain complaints. Cannabis and Cannabinoid Research, 5(3), 255–262.
Revicki, D. A., Cook, K. F., Amtmann, D., Harnam, N., Chen, W. H., & Keefe, F. J. (2014). Exploratory and confirmatory factor analysis of the PROMIS pain quality item bank. Quality of Life Research, 23(1), 245–255.
Vaughan, B., Chase, B., Hickey, J., Tassoulas, M., Weston, H., Fitzgerald, K., Fleischmann, M., Mulcahy, J., & Austin, P. (2021). PROMIS neuropathic and nociceptive pain quality in musculoskeletal pain presentations. Clinical Journal of Pain, 37(9), 639–647.
|Variable Name||Variable ID||Variable Description||dbGaP Mapping|
|PX860704040000||Did your pain feel electrical?||N/A|
|PX860704050000||Did your pain feel numb?||N/A|
|PX860704010000||Did your pain feel like pins and needles?||N/A|
|PX860704030000||Did your pain feel stinging?||N/A|
|PX860704020000||Did your pain feel tingly?||N/A|
Pain Quality Descriptors
July 28, 2022
A measure used to assess the specific subjective sensations associated with pain.
Assessing the nature of pain an individual experiences may assist in indicating whether the pain is primarily nociceptive or neuropathic. This can aid in the selection of appropriate treatment and in evaluating a patient's response to treatment.
Pain, affective, sickle cell disease, SCD, pain quality, pain measurement, pain assessment, Patient-Reported Outcomes Measurement Information System, PROMIS®, National Institutes of Health, NIH, type I diabetes, asthma
|Protocol ID||Protocol Name|
|860701||Pain Quality Descriptors (Affective) - Children|
|860702||Pain Quality Descriptors (Sensory) - Children|
|860703||Pain Quality Descriptors (Nociceptive) - Adult|
|860704||Pain Quality Descriptors (Neuropathic) - Adult|
There are no publications listed for this protocol.