Protocol - Depression Screener - Adults

Personnel and Training Required

The interviewer must be trained to conduct personal interviews with individuals from the general population. The interviewer must be trained and found to be competent (i.e., tested by an expert) at the completion of personal interviews. The interviewer should be trained to prompt respondents further if a "don’t know" response is provided.

Equipment Needs

None

Requirements

Requirement Category	Required
Major equipment	No
Specialized training	No
Specialized requirements for biospecimen collection	No
Average time of greater than 15 minutes in an unaffected individual	No

Mode of Administration

Interviewer-administered questionnaire

Lifestage

Adult

Participants

Adults, ages 18 or older.

Selection Rationale

The Composite International Diagnostic Interview Screening Scales (CIDI-SC) 5.0 was selected to screen a general population for the presence of depression because it is based on the larger Composite International Diagnostic Interview (CIDI). The CIDI has been used on thousands of subjects in the United States and around the world, is available in multiple formats, is easily administered by trained nonclinician interviewers, and is well validated. The CIDI provides screening criteria consistent with the International Statistical Classification of Diseases and Related Health Problems 10th Revision (ICD-10) and the Diagnostic and Statistical Manual of Mental Disorders (5th ed.; DSM-5).

Language

English

Standards

Standard	Name	ID	Source
Human Phenotype Ontology	Depression	HP:0000716	HPO

Derived Variables

None

Process and Review

Expert Review Panel 4 (ERP 4) reviewed the measures in the Neurology, Psychiatric, and Psychosocial domains.

Guidance from ERP 4 included the following:

• Updated protocol
• Changed measure name
• Created new data dictionary

Previous version in Toolkit archive (link)

Protocol Name from Source

Composite International Diagnostic Interview Screening Scales (CIDI-SC) 5.0, Depression

Source

The Composite International Diagnostic Interview Screening Scales (CIDI-SC) 5.0 for the Diagnostic and Statistical Manual of Mental Disorders (5th ed.; DSM-5) are available from Dr. Ronald C. Kessler:

Ronald C. Kessler, PhD
Department of Health Care Policy, Harvard Medical School
180 Longwood Avenue
Boston, MA 02115
USA
kessler@hcp.med.harvard.edu

General References

Kessler, R. C., Calabrese, J. R., Farley, P. A., Gruber, M. J., Jewell, M. A., Katon, W., Keck, P. E., Nierenberg, A. A., Sampson, N. A., Shear, M. K., Shillington, A. C., Stein, M. B., Thase, M. E., & Wittchen, H. U. (2013). Composite International Diagnostic Interview screening scales for DSM-IV anxiety and mood disorders. Psychological Medicine, 43(8), 1625-1637.

Kessler, R. C., Santiago, P. N., Colpe, L. J., Dempsey, C. L., First, M. B., Heeringa, S. G., Stein, M. B., Fullerton, C. S., Gruber, M. J., Naifeh, J. A., Nock, M. K., Sampson, N. A., Schoenbaum, M., Zaslavsky, A. M., & Ursano, R. J. (2013). Clinical reappraisal of the Composite International Diagnostic Interview Screening Scales (CIDI-SC) in the Army Study to Assess Risk and Resilience in Service members (Army STARRS). International Journal of Methods in Psychiatric Research, 22(4), 303-321.

Protocol ID

120503

Variables

Export Variables

Variable Name	Variable ID	Variable Description	dbGaP Mapping
	PX120503000000	Protocol 120503 - proprietary. Check DCW for more contact. show less	N/A

Psychiatric

Measure Name

Depression Screener

Release Date

November 28, 2017

Definition

An interviewer-administered questionnaire to screen for major depressive disorder (MDD).

Purpose

This measure can be used to screen an individual for the presence of depression and to assess the degree of distress and impairment. Depression is a common disorder that demonstrates a familial pattern and is comorbid with other psychiatric disorders, including anxiety disorder, substance use disorders, and eating disorders. Additionally, certain medical conditions-such as diabetes, stroke, and heart disease-can increase the risk of depression. Some individuals who present with major depressive episodes may have a bipolar spectrum disorder.

Keywords

Psychiatric, depression, bipolar disorder

Measure Protocols

Protocol ID	Protocol Name
120503	Depression Screener - Adults

Publications

Pei, Z., et al. (2022) Association between Dietary Patterns and Depression in Chinese Older Adults: A Longitudinal Study Based on CLHLS. Nutrients. 2022 December; 14(24): 5230. doi: 10.3390/nu14245230

Schettini, E., et al. (2021) Internalizing-externalizing comorbidity and regional brain volumes in the ABCD study. Development and Psychopathology. 2021 December; 33(5): 1620-1633.

Barch, D. M., et al. (2021) Demographic and mental health assessments in the adolescent brain and cognitive development study: Updates and age-related trajectories. Developmental Cognitive Neuroscience. 2021 December; 52: 101031. doi: 10.1016/j.dcn.2021.101031

Barch, D. M., et al. (2018) Demographic, physical and mental health assessments in the adolescent brain and cognitive development study: Rationale and description. Dev Cogn Neurosci. 2018 August; 32: 55-66. doi: 10.1016/j.dcn.2017.10.010

Merz, E. C., et al. (2018) Anxiety, depression, impulsivity, and brain structure in children and adolescents. Neuroimage Clin. 2018 July; 2018(20): 243-251. doi: 10.1016/j.nicl.2018.07.020

Anderson, A. J. M., et al. (2016) Development of an Inflammatory Bowel Disease Research Registry Derived from Observational Electronic Health Record Data for Comprehensive Clinical Phenotyping. Dig Dis Sci. 2016 November; 61(11): 3236-3245. doi: 10.1007/s10620-016-4278-z