Protocol - Anxiety Disorders Symptoms - Adult

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This protocol includes the anxiety subscale of the Symptom Check List 90 (SCL-90). The anxiety subscale of the SCL-90 includes self-administered questions for adults that cover primary symptom dimensions and provide an overview of the respondent’s symptoms and their intensity at a specific point in time. Each item is scored on a scale of 0 to 4 (with 0 = not at all, 1 = a little bit, 2 = moderately, 3 = quite a bit, and 4 = extremely), asking respondents which number best describes how much that problem has bothered them in the last 4 weeks.

Specific Instructions

The Symptom Checklist 90 (SCL-90) is a proprietary, fee-based instrument that is available from Pearson Education, Inc.


Limited Availability


Symptom Assessment from the Symptom Check List 90

The Symptom Check List 90 is published and distributed exclusively by NCS Pearson, Inc., and can be obtained through:

Attn: Customer Service
P.O. Box 599700
San Antonio, TX 78259
Telephone: 800.627.7271
Email: clinicalcustomersupport@pearson.com

Personnel and Training Required


Equipment Needs


Requirement CategoryRequired
Major equipment No
Specialized training No
Specialized requirements for biospecimen collection No
Average time of greater than 15 minutes in an unaffected individual No
Mode of Administration

Self-administered questionnaire


Adult, Senior, Pregnancy


An individual aged 13 and older with a 6th-grade reading level.

Selection Rationale

The Symptom Check List 90 (SCL-90) was selected to provide a quantitative measure of anxiety symptoms rather than simply categorical diagnoses. SCL-90 was vetted against several other dimensional measures of anxiety disorders and ultimately selected because it is easily administered as a self-reported instrument, takes less than 15 minutes, and captures general symptoms of anxiety.


English, Other languages available at source

Human Phenotype Ontology Anxiety HP:0000739 HPO
Derived Variables


Process and Review

Expert Review Panel 4 (ERP 4) reviewed the measures in the Neurology, Psychiatric, and Psychosocial domains.

Guidance from ERP 4 includes the following:

  • New Measure

Protocol Name from Source

Symptom Check List 90 (SCL-90)


Derogatis, L. R, Lipman, R. S., & Covi, L. (1973). SCL-90: An outpatient psychiatric rating scale-Preliminary report. Psychopharmacology Bulletin, 9(1), 13-28.

The Symptom Check List 90 (SCL-90) is published and distributed exclusively by NCS Pearson, Inc., and can be obtained through:

Attn: Customer Service
P.O. Box 599700
San Antonio, TX 78259
Telephone: 800.627.7271
Email: clinicalcustomersupport@pearson.com

General References

American Psychiatric Association (APA). (2000). Diagnostic and statistical manual of mental disorders (4th ed., text rev.). Washington, DC: Author.

Dai, Y., Li, X., Zhang, X., Wang, S., Sang, J., Tian, X., & Cao, H. (2016). Prevalence and predisposing factors for depressive status in Chinese patients with obstructive sleep apnoea: A large-sample survey. PLoS ONE, 11(3), e0149939.

Kessler, R. C., Chiu, W. T., Demler, O., & Walters, E. E. (2005). Prevalence, severity, and comorbidity of twelve-month DSM-IV disorders in the National Comorbidity Survey Replication (NCS-R). Archives of General Psychiatry, 62(6), 617-627.

Loesch, D. Z., Bui, M, Q., Hammersley, E., Schneider, A., Storey, E., Stimpson, P., Burgess, T., Francis, D., Slater, H., Tassone, F., Hagerman, R. J., & Hessl, D. (2015). Psychological status in female carriers of premutation FMR1 allele showing a complex relationship with the size of CGG expansion. Clinical Genetics, 87(2), 173-178.

Protocol ID


Export Variables
Variable Name Variable IDVariable DescriptiondbGaP Mapping
PX121803000000 Protocol 121803 - proprietary. Check DCW for more
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Measure Name

Anxiety Disorders Symptoms

Release Date

November 28, 2017


A questionnaire to assess anxiety disorders, which include a number of different conditions such as panic disorder, generalized anxiety disorder, social phobia, specific phobia, agoraphobia, obsessive-compulsive disorder, and posttraumatic stress disorder (APA, 2000).


This measure is used to screen an individual for the presence of anxiety disorders and to assess the severity of underlying symptoms. Anxiety disorders are one of the most prevalent psychiatric conditions occurring in about 18 percent of the population (Kessler et al., 2005). Anxiety disorders may be influenced by genetics and environmental factors and commonly occur with other physical conditions, such as cardiovascular, respiratory, and gastrointestinal disease, as well as with other mental illnesses such as depression and substance abuse disorders (APA, 2000). Furthermore, a significant proportion of pediatric psychiatric patients have anxiety disorders.


Psychiatric, phobia

Measure Protocols
Protocol ID Protocol Name
121801 Anxiety Disorders Symptoms - Children - Parent Report
121802 Anxiety Disorders Symptoms - Children - Self-Report
121803 Anxiety Disorders Symptoms - Adult

There are no publications listed for this protocol.