Protocol - Acute Subjective Response to Substances - Current - Specific - Alcohol
- Age of Initiation of First Cigarette Use - Adult
- Alcohol - 30-Day Quantity and Frequency
- Alcohol - Age of First Use
- Alcohol - Lifetime Use Disorder
- Alcohol - Maximum Drinks in 24 Hours
- Cigarette Nicotine Dependence
- Substances - 30-Day Frequency
- Substances - Age of First Use
- Substances - Lifetime Abuse and Dependence
- Tobacco - 30-Day Quantity and Frequency - Adolescent
- Tobacco - 30-Day Quantity and Frequency - Adult
- Tobacco - Age of Initiation of Use - Adolescent
Description
The Biphasic Alcohol Effects Scale (BAES) is a self-report, unipolar adjective rating scale after consuming alcohol that is designed to measure both stimulant and sedative effects of alcohol.
Specific Instructions
The BAES may be used in laboratory studies involving alcohol administration to study responses to alcohol. The investigator may administer a fixed dose of alcohol or a placebo to a respondent in the form of a beverage or intravenously, or the investigator may allow the respondent to control the amount of alcohol he/she receives. Typically, baseline assessments are obtained prior to alcohol administration and then at predetermined points following drinking. In fixed-dose studies, the BAES is often repeated at time points corresponding to the rising and falling portions of the blood alcohol curve.
The Substance Abuse and Addiction Working Group acknowledges that the following questions may gather sensitive information relating to the use of substances and/or illegal conduct. If the information is released, it might be damaging to an individual’s employability, lead to social stigmatization, or lead to other consequences.
Most researchers assure confidentiality as part of their informed consent process, as required by their institutional review boards. Further assurance of confidentiality may be obtained by applying to the National Institutes of Health (NIH) for a Certificate of Confidentiality, which helps researchers protect the privacy of human research participants. The procedures for the Certificate of Confidentiality can be found at the Grants Policy website of NIH: http://grants1.nih.gov/grants/policy/coc/index.htm.
Availability
Protocol
A baseline assessment of how the person feels may be obtained prior to alcohol administration by using the following instructions:
Please rate the extent to which these words describe your feelings at the present time (circle the appropriate number for each word).
To measure responses following alcohol consumption, the following instructions are used:
The following adjectives describe feelings that some people have after drinking alcohol. Please rate the extent to which drinking alcohol has produced these feelings in you at the present time (circle the appropriate number for each word).
| Not at all | Extremely | |||||||||||||
| 1. Difficulty concentrating | 0 | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | |||
| 2. Down | 0 | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | |||
| 3. Elated | 0 | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | |||
| 4. Energized | 0 | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | |||
| 5. Excited | 0 | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | |||
| 6. Heavy head | 0 | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | |||
| 7. Inactive | 0 | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | |||
| 8. Sedated | 0 | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | |||
| 9. Slow thoughts | 0 | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | |||
| 10. Sluggish | 0 | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | |||
| 11. Stimulated | 0 | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | |||
| 12. Talkative | 0 | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | |||
| 13. Up | 0 | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | |||
| 14. Vigorous | 0 | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | |||
Scoring Procedures and Interpretation
The Sedation and Stimulation subscales are calculated by summing the following items (for the 14-point scale):
Stimulation: = BAES3 + BAES4 + BAES5 + BAES11 + BAES12 + BAES13 +BAES14
Sedation: = BAES1 + BAES2 + BAES6 + BAES7 + BAES8 + BAES9 + BAES10
Personnel and Training Required
None
Equipment Needs
None
Requirements
| Requirement Category | Required |
|---|---|
| Major equipment | No |
| Specialized training | No |
| Specialized requirements for biospecimen collection | No |
| Average time of greater than 15 minutes in an unaffected individual | No |
Mode of Administration
Self-administered questionnaire
Lifestage
Adult, Senior
Participants
Adults aged 18 years and older
Selection Rationale
The 14-item Biphasic Alcohol Effects Scale (BAES) was selected because it is one of the most widely used subjective alcohol assessment tools in studies involving actual administration of alcohol. It is sensitive to the stimulant and sedative effects of alcohol observed during the ascending and descending limbs of the blood alcohol curve. It is reliable, has good test psychometric properties, and can be used repeatedly within a session. A brief six-item version of the BAES has also been developed (Rueger et al., 2009).
Language
English
Standards
| Standard | Name | ID | Source |
|---|---|---|---|
| Human Phenotype Ontology | Addictive behavior | HP:0030858 | HPO |
| caDSR Form | PhenX PX520102 - Acute Subjective Resp To Substcurrentspecificalcoho | 6216779 | caDSR Form |
Derived Variables
None
Process and Review
The Expert Review Panel #3 (ERP 3) reviewed the measures in Alcohol, Tobacco and Other Substances, and Substance Abuse and Addiction domains.
Guidance from ERP 3 includes:
• Revised descriptions of the measure
Back-compatible: NA no changes to Data Dictionary
Previous version in Toolkit archive (link)
Protocol Name from Source
Biphasic Alcohol Effects Scale (BAES)
Source
Martin, C. S., Earleywine, M., Musty, R. E., Perrine, M. W., & Swift R. M. (1993). Development and validation of the Biphasic Alcohol Effects Scale. Alcoholism: Clinical and Experimental Research, 17(1), 140-146.
General References
Earleywine, M, & Erblich, J. (1996). A confirmed factor structure for the Biphasic Alcohol Effects Scale. Experimental and Clinical Psychopharmacology, 4(1), 107-113.
Morean, M. E., & Corbin, W. R. (2010). Subjective response to alcohol: A critical review of the literature. Alcoholism: Clinical and Experimental Research, 34(3), 385-395.
Quinn, P. D., & Fromme, K. (2011). Subjective response to alcohol challenge: A quantitative review. Alcoholism: Clinical and Experimental Research, 35(10), 1-12.
Rueger, S. Y., McNamara, P. J., & King, A. C. (2009). Expanding the utility of the Biphasic Alcohol Effects Scale (BAES) and initial psychometric support for the Brief-BAES (B-BAES). Alcoholism: Clinical and Experimental Research, 33(5), 916-924.
Rueger, S. Y., & King, A. C. (2013). Validation of the Brief Biphasic Alcohol Effects Scale (B-BAES). Alcoholism: Clinical and Experimental Research, 37(3),470-476
Protocol ID
520102
Variables
Export Variables| Variable Name | Variable ID | Variable Description | dbGaP Mapping | |
|---|---|---|---|---|
| PX520102._Difficulty_Concentrating | ||||
| PX520102010000 | The following adjectives describe feelings more | N/A | ||
| PX520102_Down | ||||
| PX520102020000 | The following adjectives describe feelings more | N/A | ||
| PX520102_Elated | ||||
| PX520102030000 | The following adjectives describe feelings more | N/A | ||
| PX520102_Energized | ||||
| PX520102040000 | The following adjectives describe feelings more | N/A | ||
| PX520102_Excited | ||||
| PX520102050000 | The following adjectives describe feelings more | N/A | ||
| PX520102_Heavy_Head | ||||
| PX520102060000 | The following adjectives describe feelings more | N/A | ||
| PX520102_Inactive | ||||
| PX520102070000 | The following adjectives describe feelings more | N/A | ||
| PX520102_Sedated | ||||
| PX520102080000 | The following adjectives describe feelings more | N/A | ||
| PX520102_Slow_Thoughts | ||||
| PX520102090000 | The following adjectives describe feelings more | N/A | ||
| PX520102_Sluggish | ||||
| PX520102100000 | The following adjectives describe feelings more | N/A | ||
| PX520102_Stimulated | ||||
| PX520102110000 | The following adjectives describe feelings more | N/A | ||
| PX520102_Talkative | ||||
| PX520102120000 | The following adjectives describe feelings more | N/A | ||
| PX520102_Up | ||||
| PX520102130000 | The following adjectives describe feelings more | N/A | ||
| PX520102_Vigorous | ||||
| PX520102140000 | The following adjectives describe feelings more | N/A | ||
Measure Name
Acute Subjective Response to Substances - Current
Release Date
February 24, 2012
Definition
Instruments used separately to assess current acute subjective responses to substances that the respondent has recently ingested or used.
Purpose
This measure is to assess a respondent’s feelings after recently smoking cigarettes, ingesting alcohol, or using drugs. The protocol is used to obtain subjective responses to the tobacco, alcohol, or drug administered. The Working Group recommends that investigators use the primary protocol to obtain general information on a variety of substances. The secondary protocols can then be used to obtain detailed information on a specific substance.
Keywords
Addiction Research Center Inventory, Adjective Checklist, alcohol, Amphetamine, ARCI, BAES, Benzedrine, Biphasic Alcohol Effects Scale, Buzz, cigarettes, dizziness, DEQ, Drug Effects Questionnaire, Early Response, Irritable, LSD, marijuana, mCEQ, modified Cigarette Evaluation Questionnaire, Morphine-Benzedrine, National Institute of Mental Health Addiction Research Center, Nausea, Pentobarbital-Chlorpromazine-Alcohol, Rush, SAA, smoking, substance abuse, Substance-specific Intermediate Phenotypes
Measure Protocols
| Protocol ID | Protocol Name |
|---|---|
| 520101 | Acute Subjective Response to Substances - Current - Specific - Drugs |
| 520102 | Acute Subjective Response to Substances - Current - Specific - Alcohol |
| 520103 | Acute Subjective Response to Substances - Current - General |
| 520104 | Acute Subjective Response to Substances - Current - Specific - Tobacco |
Publications
Lisdahl, K. M., et al. (2018) Adolescent brain cognitive development (ABCD) study: Overview of substance use assessment methods. Dev Cogn Neurosci. 2018 August; 32: 80-96. doi: 10.1016/j.dcn.2018.02.007