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Protocol - Acute Subjective Responses to Substances - Retrospective - Tobacco

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Description

This instrument uses a set of self-administered questions to assess early response to tobacco smoking, and it may also be used for marijuana smoking. Seven items inquire about pleasant and unpleasant experiences and ask respondents if they encountered various effects while smoking a tobacco cigarette for the first time. Pleasurable and unpleasant sensations are rated on a scale ranging from 1 for "none" to 4 for "intense." Pleasurable rush or buzz, relaxation, nausea, cough, and dizziness are checked "yes" or "no," depending on the respondent’s experience.

Specific Instructions

These questions are only asked if a respondent had affirmatively answered one of the questions in the "Tobacco - Smoking Status" measure. This questionnaire provides a qualitative description of the nature of early smoking experiences, so there are no specific scoring instructions.

The Substance Abuse and Addiction Working Group acknowledges that the following questions may gather sensitive information relating to the use of substances and/or illegal conduct. If the information is released, it might be damaging to an individual’s employability, lead to social stigmatization, or lead to other consequences.

Most researchers assure confidentiality as part of their informed consent process, as required by their institutional review boards. Further assurance of confidentiality may be obtained by applying to the National Institutes of Health (NIH) for a Certificate of Confidentiality, which helps researchers protect the privacy of human research participants. The procedures for the Certificate of Confidentiality can be found at the Grants Policy website of NIH: http://grants1.nih.gov/grants/policy/coc/index.htm.

Availability

Available

Protocol

Please rate the extent to which these words describe your feelings the very first time you smoked a cigarette. The number 1 indicates none, and 4 represents intense.

1. While smoking your very first cigarette, did you have pleasurable sensations?

1[ ]None

2[ ]

3[ ]

4[ ]Intense

2. While smoking your very first cigarette, did you have unpleasant sensations?

1[ ]None

2[ ]

3[ ]

4[ ]Intense

Please answer yes or no to the following questions about the very first cigarette you smoked.

3. While smoking your very first cigarette, did you have a pleasurable buzz or rush?

[ ] Yes

[ ] No

4. While smoking your very first cigarette, did you feel relaxed?

[ ] Yes

[ ] No

5. While smoking your very first cigarette, did you feel dizzy?

[ ] Yes

[ ] No

6. While smoking your very first cigarette, did you have nausea?

[ ] Yes

[ ] No

7. While smoking your very first cigarette, did you cough?

[ ] Yes

[ ] No

8. Were you alone the first time you experimented with cigarettes?

[ ] Yes

[ ] No

Personnel and Training Required

None

Equipment Needs

None

Requirements
Requirement CategoryRequired
Major equipment No
Specialized training No
Specialized requirements for biospecimen collection No
Average time of greater than 15 minutes in an unaffected individual No
Mode of Administration

Self-administered questionnaire

Lifestage

Adult, Senior

Participants

Adults aged 18 years and older

Selection Rationale

This adjective checklist has been widely adopted and validated for tobacco use. An adjective checklist is also available for marijuana, but its application is limited as compared to this adjective checklist being recommended for tobacco.

Language

English

Standards
StandardNameIDSource
Human Phenotype Ontology Addictive behavior HP:0030858 HPO
caDSR Form PhenX PX520201 - Acute Subj Responses To Substretrospectivetobacco 6217190 caDSR Form
Derived Variables

None

Process and Review

The Expert Review Panel #3 (ERP 3) reviewed the measures in Alcohol, Tobacco and Other Substances, and Substance Abuse and Addiction domains.

Guidance from ERP 3 includes:

• No significant changes to measure

Back-compatible: NA no changes to Data Dictionary

Protocol Name from Source

Pomerleau et al, Early experiences with tobacco among women smokers, ex-smokers, and never-smokers, ADDICTION, 1998

Source

Pomerleau, O. F., Pomerleau, C. S., & Namenek, R. J. (1998). Early experiences with tobacco among women smokers, ex-smokers, and never-smokers. Addiction, 93(4), 595-599.

General References

Fergusson, D. M., Horwood, J. L., Lynskey, M. T., & Madden, P. A. (2003). Early reactions to cannabis predict later dependence. Archives of General Psychiatry, 60(10), 1033-1039.

Haberstick, B. C., Ehringer, M. A., & Lessem, J. M. (2011). Dizziness and the genetic influences on subjective experiences to initial cigarette use. Addiction, 106(2), 391-399.

Perkins, K. A., Lerman, C., Coddington, S., & Karelitz, J. L. (2008). Association of retrospective early smoking experiences with prospective sensitivity to nicotine via nasal spray in nonsmokers. Nicotine and Tobacco Research, 10(8), 1335-1345.

Protocol ID

520201

Variables
Export Variables
Variable Name Variable IDVariable DescriptiondbGaP Mapping
PX520201_First_Cigarette_Alone
PX520201080000 Were you alone the first time you more
experimented with cigarettes? show less
N/A
PX520201_First_Cigarette_Buzz_Or_Rush
PX520201030000 While smoking your very first cigarette, did more
you have a pleasurable buzz or rush? show less
N/A
PX520201_First_Cigarette_Cough
PX520201070000 While smoking your very first cigarette, did more
you cough? show less
N/A
PX520201_First_Cigarette_Feel_Dizzy
PX520201050000 While smoking your very first cigarette, did more
you feel dizzy? show less
N/A
PX520201_First_Cigarette_Feel_Relaxed
PX520201040000 While smoking your very first cigarette, did more
you feel relaxed? show less
N/A
PX520201_First_Cigarette_Nausea
PX520201060000 While smoking your very first cigarette, did more
you have nausea? show less
N/A
PX520201_First_Cigarette_Pleasurable_Sensations
PX520201010000 While smoking your very first cigarette, did more
you have pleasurable sensations? show less
N/A
PX520201_First_Cigarette_Unpleasant_Sensations
PX520201020000 While smoking your very first cigarette, did more
you have unpleasant sensations? show less
N/A
Substance-specific Intermediate Phenotypes
Measure Name

Acute Subjective Responses to Substances - Retrospective

Release Date

February 24, 2012

Definition

Instruments used separately to assess acute subjective response to substances in the past.

Purpose

The purpose of this measure is to assess acute subjective response to substances (namely, tobacco and alcohol) in the past. Although individual researchers have designed and used their own measures to assess effects of other drugs (e.g., opiates, methamphetamine, and cocaine), at the time the measures were selected for inclusion in the Toolkit, this Working Group was unable to identify a retrospective measure for other drugs that was well-established and broadly applicable.

Keywords

Acute Subjective Response to Drugs, Adjective Checklist, Alcoholism, Buzz, dizziness, Early Response, Level of Response, Nausea, Pass Out, Prediction, Relaxation, Rush, SAA, Self-Rating of the Effects of Alcohol, smoking, SRE, Stumbling, Tolerance, Substance-specific Intermediate Phenotypes

Measure Protocols
Protocol ID Protocol Name
520201 Acute Subjective Responses to Substances - Retrospective - Tobacco
520202 Acute Subjective Responses to Substances - Retrospective - Alcohol
Publications

There are no publications listed for this protocol.