Protocol - Intelligence Scale - 16 to 90 years
Wechsler Adult Intelligence Scale®, Fourth Edition (WAIS®-IV), is a standardized tool designed to assess an individual’s cognitive abilities. The WAIS®-IV consists of a battery of tests that allow an investigator to conduct a comprehensive cognitive evaluation of IQ. The WAIS®-IV is a proprietary instrument and is available online from Pearson at www.pearsonclinical.com.
The Wechsler Adult Intelligence Scale®, Fourth Edition (WAIS®-IV) is a proprietary instrument and is available online from Pearson at www.pearsonclinical.com.
The Sickle Cell Disease Neurology, Quality of Life, and Health Services Working Group recognizes that there is an age overlap between the WAIS®-IV and the Wechsler Intelligence Scale for Children®-Fifth Edition (WISC®-V). The Working Group recommends providers use their clinical judgment, consider the purpose of testing participants, and refer to the frequently asked questions section of the Pearson website for the WAIS®-IV and the WISC®-V for guidance on selecting an age-appropriate test for individuals.
Wechsler Adult Intelligence Scale®, Fourth Edition (WAIS®-IV), is a tool designed to assess an individual’s cognitive abilities and is administrated by a trained psychologist using a combination of verbal and performance tasks. The WAIS®-IV consists of a core battery of 10 subtests, which focus on specific intelligence domains (perceptual reasoning, processing speed, verbal comprehension, and working memory).
The WAIS®-IV is a proprietary instrument and is available online from Pearson at www.pearsonclinical.com.
Personnel and Training Required
The interviewer should be a licensed professional (or someone directly supervised by a licensed professional) who has been trained and is competent in the administration, scoring, and interpretation of standardized psychometric assessment tools, such as the Wechsler Adult Intelligence Scale®, Fourth Edition (WAIS®-IV), and meets the requirements of Qualification Level C for test use and administration.
Per the Pearson website, a test with a qualification of C, "require(s) a high level of expertise in test interpretation, and can be purchased by individuals with the following:
A doctorate degree in psychology, education, or closely related field with formal training in the ethical administration, scoring, and interpretation of clinical assessments related to the intended use of the assessment.
Licensure or certification to practice in your state in a field related to the purchase.
Certification by or full active membership in a professional organization (such as APA, NASP, NAN, INS) that requires training and experience in the relevant area of assessment.
The interviewer will require the Wechsler Adult Intelligence Scale®, Fourth Edition (WAIS®-IV). The Sickle Cell Disease Neurology, Quality of Life, and Health Services Working Group acknowledges the WAIS®-IV can be scored in a computerized format or a paper-and-pencil instrument. Computer software is necessary to develop computer-assisted instruments. The interviewer will require a laptop computer/handheld computer to administer a computer-assisted questionnaire.
|Specialized requirements for biospecimen collection||No|
|Average time of greater than 15 minutes in an unaffected individual||Yes|
Mode of Administration
Individuals from 16 to 90 years old
The Sickle Cell Disease Neurology, Quality of Life, and Health Services Working Group selected the Wechsler Adult Intelligence Scale®, Fourth Edition (WAIS®-IV), because it is a well-validated tool that yields IQ and various functional index scores.
|caDSR Common Data Elements (CDE)||Adult Intelligence Quotient Questionnaire Assessment Scale||4922474||CDE Browser|
|Human Phenotype Ontology||Sickle Cell Anemia||ORPHA:232||HPO|
|Human Phenotype Ontology||Anemia||OMIM:603903||HPO|
Process and Review
Protocol Name from Source
Wechsler Adult Intelligence Scale, 4th ed., (WAIS-IV)
Wechsler, D. (2008). Wechsler Adult Intelligence Scale®, Fourth Edition (WAIS®-IV). Pearson Assessments.
The Wechsler Adult Intelligence Scale®, Fourth Edition (WAIS®-IV) is proprietary instrument and can be obtained through
Hijmans, C, T., Fijnvandraat, K., Grootenhuis, M. A., van Geloven, N., Heijboer, H., Peters, M., & Oosterlaan, J. (2011). Neurocognitive deficits in children with sickle cell disease: a comprehensive profile. Pediatric Blood & Cancer 56(5), 783-788.
Mackin, R. S., Insel, P., Truran, D., Vichinsky, E. P., Neumayr, L. D., Armstrong, F. D., Gold, J.I., Kesler, K., Brewer, J., Weiner, M.W., Neuropsychological Dysfunction and Neuroimaging Adult Sickle Cell Anemia Study Group. (2014). Neuroimaging abnormalities in adults with sickle cell anemia: associations with cognition. Neurology, 82(10), 835-841.
Tarazi, R. A., Grant, M. L., Ely, E., & Barakat, L. P. (2007). Neuropsychological functioning in preschool-age children with sickle cell disease: The role of illness-related and psychosocial factors. Child Neuropsychology 13(2), 155-172.
Vichinsky, E. P., Neumayr, L. D., Gold, J. I., Weiner, M. W., Rule, R. R., Truran, D., Kasten, J., Eggleston, B., Kesler, K., McMahon, L., Orringer, E.P., Harrington, T., Kalinyak, K., De Castro, L.M., Kutlar, A., Rutherford, C.J., Johnson, C., Bessman, J.D., Jordan, L.B., Armstrong, F.D; Neuropsychological Dysfunction and Neuroimaging Adult Sickle Cell Anemia Study Group. (2010). Neuropsychological dysfunction and neuroimaging abnormalities in neurologically intact adults with sickle cell anemia. Journal of the American Medical Association 303(18), 1823-1831
|Variable Name||Variable ID||Variable Description||dbGaP Mapping|
|PX820501000000||Protocol 820501 - proprietary. Check DCW for more||N/A|
July 30, 2015
This measure provides an estimate of an individual’s overall global intellectual function.
Impairments in general cognitive function, as measured by the intelligence quotient (IQ), are associated with some genetic diseases (e.g., Down’s syndrome, Fragile X syndrome, sickle cell disease [SCD]), stroke, prematurity, nutritional deficiencies, and use of drugs and alcohol.
Bayley Scales of Infant and Toddler Development®, Third Edition, Bayley-III®, Wechsler Preschool and Primary Scale of Intelligence™-Fourth Edition, WPPSI™-IV, Wechsler Intelligence Scale for Children®-Fifth Edition, WISC®-V, Wechsler Adult Intelligence Scale®, Fourth Edition, WAIS®-IV, Infant, Child, Toddler, Adolescent, Teen, Elderly, Developmental delay, Cognitive development, Cognitive ability, Cognitive decline, Learning disability, Psychological disability, Global intelligence, IQ, Sickle cell disease, SCD, Traumatic brain injury, TBI, Brain injury, Autism, Autism Spectrum Disorders, ASD, Alzheimer’s disease, Dementia, Senility, Neurology, Academically gifted, Intellectual giftedness, Intelligence scale, Down’s syndrome, Fragile X syndrome, FXS, Prematurity, Nutritional deficiencies, "Neurology, Quality of Life, and Health Services"
|Protocol ID||Protocol Name|
|820501||Intelligence Scale - 16 to 90 years|
|820502||Intelligence Scale - 2 years, 6 months to 7 years, 7 months|
|820503||Intelligence Scale - 6 to 16 years 11 months|
|820504||Intelligence Scale - Birth to 3.5 years|
There are no publications listed for this protocol.