Protocol - Intelligence Scale - Birth to 3.5 years
The Bayley Scales of Infant and Toddler Development®, Third Edition (Bayley-III®) is a standardized tool designed to assess a child’s development as compared to same-age peers. The Bayley-III® has components that involve both direct observation and interaction with a child as well as caregiver questionnaires. The Bayley-III® is a proprietary instrument and is available online from Pearson at www.pearsonclinical.com.
The Bayley Scales of Infant and Toddler Development®, Third Edition (Bayley-III®) is a proprietary instrument and is available on line from Pearson at www.pearsonclinical.com. A fee is associated with the Bayley-III®, and this fee is dependent upon various factors, such as if the Bayley-III® is purchased as a kit (i.e., questionnaires, manuals, or forms) or in individual components.
The Sickle Cell Disease Neurology, Quality of Life, and Health Services Working Group recognizes that there is an age overlap between the Bayley-III® and the Wechsler Preschool and Primary Scale of Intelligence™-Fourth Edition (WPPSI™ - IV). The Working Group recommends that providers use their clinical judgment, consider the purpose of testing participants, and refer to the frequently asked questions section of the Pearson website for Bayley-III® and the WPPSI™-IV for guidance on selecting an age-appropriate test.
The Bayley Scales of Infant and Toddler Development®, Third Edition (Bayley-III®) consists of five domains (cognitive, motor, language, social-emotional, and adaptive behavior).
The Bayley-III® is a proprietary instrument and is available on line from Pearson at www.pearsonclinical.com. A fee is associated with the Bayley-III®, and this fee is dependent upon various factors, such as if the Bayley-III® is purchased as a kit (i.e., questionnaires, manuals, or forms) or in individual components.
Personnel and Training Required
The interviewer should be a licensed professional (or someone directly supervised by a licensed professional) who has been trained and is competent in the administration, scoring, and interpretation of standardized psychometric assessment tools such as the Bayley-III® and who meets the requirements of Qualification Level C for test use and administration.
These skills are typically part of the skill set of an individual with at least a master’s degree. Professionals with the required training are usually speech and language therapists, early interventionists, social workers, occupational and physical therapists specializing in early intervention, developmental pediatricians, pediatric nurse practitioners, psychologists, and psychiatrists.
The Bayley-III® has a qualification level of C. Per the Pearson website, tests with a qualification of C "require a high level of expertise in test interpretation, and can be purchased by individuals with the following:
A doctorate degree in psychology, education, or closely related field with formal training in the ethical administration, scoring, and interpretation of clinical assessments related to the intended use of the assessment.
Licensure or certification to practice in your state in a field related to the purchase.
Certification by or full active membership in a professional organization (such as APA, NASP, NAN, INS) that requires training and experience in the relevant area of assessment.
The interviewer will require the Bayley Scales of Infant and Toddler Development®, Third Edition (Bayley-III®). The Sickle Cell Disease Neurology, Quality of Life, and Health Services Working Group acknowledges that the Bayley-III® can be scored in a computerized format or as a paper-and-pencil instrument. Computer software is necessary to develop computer-assisted instruments. The interviewer will require a laptop computer/handheld computer to administer a computer-assisted questionnaire.
|Specialized requirements for biospecimen collection||No|
|Average time of greater than 15 minutes in an unaffected individual||Yes|
Mode of Administration
Infant, Toddler, Child
Children from birth to age 3 years, 6 months
The Sickle Cell Disease Neurology, Quality of Life, and Health Services Working Group selected the Bayley Scales of Infant and Toddler Development®, Third Edition (Bayley-III®) because it is a well-validated, widely used instrument with an objective, age-normed evaluation of developmental function.
|caDSR Common Data Elements (CDE)||Infant Intelligence Quotient Questionnaire Assessment Scale||4922483||CDE Browser|
|Human Phenotype Ontology||Sickle Cell Anemia||ORPHA:232||HPO|
|Human Phenotype Ontology||Anemia||OMIM:603903||HPO|
Process and Review
Protocol Name from Source
Bayley, N. (2005). Bayley Scales of Infant and Toddler Development®, Third Edition (Bayley-III®). Pearson Assessments.
The Bayley Scales of Infant and Toddler Development®, Third Edition (Bayley-III®) is proprietary instrument and can be obtained through
Connolly, A. M., Florence, J. M., Cradock, M. M., Eagle, M., Flanigan, K. M., McDonald, C.M., Karachunski, P.I., Darras, B.T., Bushby, K., Malkus, E.C., Golumbek, P.T., Zaidman, C.M., Miller, J.P., Mendell, J.R.; MDA DMD Clinical Research Network. (2014). One year outcome of boys with Duchenne muscular dystrophy using the Bayley-III scales of infant and toddler development. Pediatric Neurology, 50(6), 557-563.
Hijmans, C. T., Fijnvandraat, K., Grootenhuis, M. A., van Geloven, N., Heijboer, H., Peters, M., & Oosterlaan, J. (2011). Neurocognitive deficits in children with sickle cell disease: a comprehensive profile. Pediatric Blood and Cancer 56(5), 783-788.
Mackin, R. S., Insel, P., Truran, D., Vichinsky, E. P., Neumayr, L. D., Armstrong, F. D., Gold, J.I., Kesler, K., Brewer, J., Weiner, M.W., Neuropsychological Dysfunction and Neuroimaging Adult Sickle Cell Anemia Study Group. (2014). Neuroimaging abnormalities in adults with sickle cell anemia: associations with cognition. Neurology, 82(10), 835-841.
Tarazi, R. A., Grant, M. L., Ely, E., & Barakat, L. P. (2007). Neuropsychological functioning in preschool-age children with sickle cell disease: The role of illness-related and psychosocial factors. Child Neuropsychology 13(2), 155-172.
Torras-Mañá, M., Guillamón-Valenzuela, M., Ramírez-Mallafré, A., Brun-Gasca, C., & Fornieles-Deu, A. (2014). Usefulness of the Bayley scales of infant and toddler development, 3rd edition, in the early diagnosis of language disorder. Psicothema, 26(3), 349-356.
Vichinsky, E. P., Neumayr, L. D., Gold, J. I., Weiner, M. W., Rule, R. R., Truran, D., Kasten, J., Eggleston, B., Kesler, K., McMahon, L., Orringer, E.P., Harrington, T., Kalinyak, K., De Castro, L.M., Kutlar, A., Rutherford, C.J., Johnson, C., Bessman, J.D., Jordan, L.B., Armstrong, F.D; Neuropsychological Dysfunction and Neuroimaging Adult Sickle Cell Anemia Study Group. (2010). Neuropsychological dysfunction and neuroimaging abnormalities in neurologically intact adults with sickle cell anemia. Journal of the American Medical Association, 303(18), 1823-1831.
|Variable Name||Variable ID||Variable Description||dbGaP Mapping|
|PX820504000000||Protocol 820504 - proprietary. Check DCW for more||N/A|
July 30, 2015
This measure provides an estimate of an individual’s overall global intellectual function.
Impairments in general cognitive function, as measured by the intelligence quotient (IQ), are associated with some genetic diseases (e.g., Down’s syndrome, Fragile X syndrome, sickle cell disease [SCD]), stroke, prematurity, nutritional deficiencies, and use of drugs and alcohol.
Bayley Scales of Infant and Toddler Development®, Third Edition, Bayley-III®, Wechsler Preschool and Primary Scale of Intelligence™-Fourth Edition, WPPSI™-IV, Wechsler Intelligence Scale for Children®-Fifth Edition, WISC®-V, Wechsler Adult Intelligence Scale®, Fourth Edition, WAIS®-IV, Infant, Child, Toddler, Adolescent, Teen, Elderly, Developmental delay, Cognitive development, Cognitive ability, Cognitive decline, Learning disability, Psychological disability, Global intelligence, IQ, Sickle cell disease, SCD, Traumatic brain injury, TBI, Brain injury, Autism, Autism Spectrum Disorders, ASD, Alzheimer’s disease, Dementia, Senility, Neurology, Academically gifted, Intellectual giftedness, Intelligence scale, Down’s syndrome, Fragile X syndrome, FXS, Prematurity, Nutritional deficiencies, "Neurology, Quality of Life, and Health Services"