Protocol - Lung Function - Diffusion Capacity

Description

The American Thoracic Society (ATS) and the European Respiratory Society (ERS) Task Force recommendations for standardisation of the single-breath determination of carbon monoxide uptake in the lung outlines principles for performing high-quality single-breath carbon monoxide diffusing capacity (D_LCO) testing. Topics covered include necessary equipment (e.g., gas analyzers), standardization issues associated with single-breath testing technique, and how to evaluate the quality of measurements of D_LCO, calculations, definitions and abbreviations.

These recommendations for the single-breath determination of carbon monoxide uptake in the lung are part of a series of recommendations by the ATS/ERS Task Force for the standardization of lung function testing, which can be found on the ATS website at www.thoracic.org/statements/pulmonary-function.php. Detailed information regarding patient preparation is included in the general considerations section of the recommendations for lung function testing in this series.

Specific Instructions

A comprehensive evaluation of lung function requires investigation of various aspects of the lung, such as diffusion capacity and lung volume. Hence, the American Thoracic Society (ATS) and the European Respiratory Society (ERS) Task Force have published a series of documents regarding pulmonary function testing. The Sickle Cell Disease: Cardiovascular, Pulmonary, and Renal Working Group recommends researchers access the ATS website (www.thoracic.org/) to view other documents in this series that may apply to their area of research.

Also please note, per www.thoracic.org/statements/resources/pft/pft4.pdf: If clinically acceptable, the subject should not breathe supplemental oxygen for 10 minutes prior to a standard test.

At least 4 minutes should be allowed between tests to allow an adequate elimination of test gas from the lungs. The subject should remain seated during this interval. In patients with obstructive airway disease, a longer period (e.g., 10 minutes) should be considered.

The average of at least two acceptable tests should be reported (i.e., outliers excluded).The report should always include the unadjusted measured carbon monoxide diffusing capacity (D_LCO), the predicted D_LCO for the subject, and percent predicted D_LCO achieved. Additionally, the alveolar volume (VA) should be obtained and the D_LCO/VA (predicted and percent predicted) should be reported. Any adjustments (e.g., for Hb, COHb, PI, or O₂,) should also be reported along with the data used to make the adjustment.

The Sickle Cell Disease Curative Therapy Working Group recommends that diffusion capacity be performed in sickle cell patients undergoing hematopoietic cell transplant at one time point pre-transplant (baseline) and 100 days, six months, and annually post- transplant.

Availability

Available

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Protocol

Lung Function Testing: Single-breath carbon monoxide diffusing capacity (D_LCO)

Personnel and Training Required

Certified respiratory therapist who is also certified in the proper use of equipment for single-breath carbon monoxide diffusing capacity (D_LCO).

Equipment Needs

A source of test gas (such as bag-in-box, spirometer, compressed gas cylinder)

A method for measuring inspired and expired volume over time (such as spirometers with kymographs, pneumotachometers near the mouthpiece or near a bag-in-box)

Gas analysers (single-sample analysers or continuous high-speed analysers)

Requirements

Requirement Category	Required
Major equipment	Yes
Specialized training	Yes
Specialized requirements for biospecimen collection	No
Average time of greater than 15 minutes in an unaffected individual	No

Mode of Administration

Clinical assessment

Lifestage

Child, Adolescent, Adult, Senior, Pregnancy

Participants

Individuals age 8 years old and older.

Selection Rationale

Although there are various methods to measure carbon monoxide diffusing capacity (D_LCO) of the lung (such as steady-state, intra-breath, and rebreathing techniques), the single-breath technique is most commonly used worldwide.

Language

English

Standards

Standard	Name	ID	Source
Human Phenotype Ontology	Abnormal DLCO	HP:0045049	HPO
caDSR Form	PhenX PX810301 - Lung Function Diffusion Capacity	6251980	caDSR Form

Derived Variables

None

Process and Review

Not applicable.

Protocol Name from Source

MacIntyre, N., et al. Standardization of the single-breath determination of carbon monoxide uptake in the lung. EUR RESPIR J, 2005

Source

MacIntyre, N., Crapo, R. O., Viegi, G., Johnson, D.C., van der Grinten, C.P.M., Brusasco, V., Burgos, F., Casaburi, R., Coates, A., Enright, P., Gustafsson, P., Hankinson, J., Jensen, R., McKay, R., Miller, M.R., Navajas, D., Pedersen, O.F., Pellegrino, R. & Wanger, J. (2005). Standardisation of the single-breath determination of carbon monoxide uptake in the lung. European Respiratory Journal, 26, 720-735. doi:10.1183/09031936.05.00034905

General References

Arteta, M., Campbell, A., Nouraie, M., Rana, S., Onyekwere, O. C., Ensing, G., Sable, C., Dham, N., Darbari, D., Luchtman-Jones, L., Kato, G. J., Gladwin, M. T., Castro, O. L., Minniti, C. P., & Gordeuk, V. R. (2014). Abnormal pulmonary function and associated risk factors in children and adolescents with sickle cell anemia. Journal of Pediatric Hematology/Oncology, 36(3), 185-189.

Lunt, A., Desai, S. R., Wells, A. U., Hansell, D. M., Mushemi, S., Melikian, N., Shah, A. M., Thein, S. L., & Greenough, A. (2014). Pulmonary function, CT and echocardiographic abnormalities in sickle cell disease, Thorax 69(8), 746-751.

Protocol ID

810301

Variables

Export Variables

Variable Name	Variable ID	Variable Description	dbGaP Mapping
PX810301_SingleBreath_CarbonMonoxide_DiffusingCapacity_Concentration_TestGas
	PX810301060000	What is the gas concentration of the test gas?	N/A
PX810301_SingleBreath_CarbonMonoxide_DiffusingCapacity_DeadSpace_Adult
	PX810301170000	For adults, is the dead space volume more consisting of the volume from the valve, filter, and mouthpiece under 0.35 Liters? show less	N/A
PX810301_SingleBreath_CarbonMonoxide_DiffusingCapacity_DeadSpace_AlveolarSample
	PX810301160100	What is the dead space volume measurement more for the alveolar sample? show less	N/A
PX810301_SingleBreath_CarbonMonoxide_DiffusingCapacity_DeadSpace_Volume
	PX810301150100	What is the dead space volume measurement more for the inspired test gas? show less	N/A
PX810301_SingleBreath_CarbonMonoxide_DiffusingCapacity_DeadSpace_VolumeMetric
	PX810301150200	How is this metric used in the more data-computation above? show less	N/A
PX810301_SingleBreath_CarbonMonoxide_DiffusingCapacity_DeadSpace_VolumeMetric2
	PX810301160200	How is this metric used in the more data-computation above? show less	N/A
PX810301_SingleBreath_CarbonMonoxide_DiffusingCapacity_Device_CoolGas
	PX810301380000	Does the device allow exhaled gases to cool more (e.g. volume to contract)? show less	N/A
PX810301_SingleBreath_CarbonMonoxide_DiffusingCapacity_Device_RemoveCo2
	PX810301360000	Does the device remove CO2 from the exhaled gas?	N/A
PX810301_SingleBreath_CarbonMonoxide_DiffusingCapacity_Device_RemoveH2o
	PX810301370000	Does the device remove H20 from the exhaled gas?	N/A
PX810301_SingleBreath_CarbonMonoxide_DiffusingCapacity_Equipment_CalibratedAccuracy
	PX810301040100	Is the device calibrated to accurately more detect the exhaled carbon monoxide and the tracer gas concentrations, which is calculated between the inhaled (test gas concentrations) and zero measurement (no CO or tracer gas present in the device)? show less	N/A
PX810301_SingleBreath_CarbonMonoxide_DiffusingCapacity_Equipment_CalibratedDeviations
	PX810301040200	If so, are the deviations from the true more measurement within 0.5% of the full scale? (for example, if 0.3% CO is used for the test gas, then the maximum error on any dilution should be no more than +/- 0.0015%) show less	N/A
PX810301_SingleBreath_CarbonMonoxide_DiffusingCapacity_Equipment_CalibratedVolume
	PX810301030000	Regardless of the method being used, does more the device maintain the required volume accuracy, regardless of the gas mixture, direction of gas flow (e.g. inhaled or exhaled), or pulsatile flow pattern? show less	N/A
PX810301_SingleBreath_CarbonMonoxide_DiffusingCapacity_Equipment_Method
	PX810301020100	Which of the following best describes the more method for measuring inspired and expired volumes over time? show less	N/A
PX810301_SingleBreath_CarbonMonoxide_DiffusingCapacity_Equipment_Method_Other
	PX810301020200	Which of the following best describes the more method for measuring inspired and expired volumes over time? Other show less	N/A
PX810301_SingleBreath_CarbonMonoxide_DiffusingCapacity_Equipment_Regulator
	PX810301110100	Is a demand-flow regulator being used on a more compressed test gas cylinder? show less	N/A
PX810301_SingleBreath_CarbonMonoxide_DiffusingCapacity_Equipment_Resistance
	PX810301110200	If no, is the circuit resistance of the more device <1.5 cm*H20/L/s at 6 L/s flow? show less	N/A
PX810301_SingleBreath_CarbonMonoxide_DiffusingCapacity_Equipment_Resistance2
	PX810301110300	If yes, is the circuit resistance of the more device <10cm H20 at 6L/s inspiratory flow? show less	N/A
PX810301_SingleBreath_CarbonMonoxide_DiffusingCapacity_Equipment_Timing
	PX810301120000	Is the timing device accurate to within 1% more (100ms over 10s)? show less	N/A
PX810301_SingleBreath_CarbonMonoxide_DiffusingCapacity_Equipment_TimingTechnique
	PX810301130000	What timing technique was used for more calibration and/or testing? show less	N/A
PX810301_SingleBreath_CarbonMonoxide_DiffusingCapacity_InspiredCO
	PX810301310000	Is the inspired CO around 0.3% of the more collected volume? show less	N/A
PX810301_SingleBreath_CarbonMonoxide_DiffusingCapacity_MeasuredConcentration_TestGas
	PX810301070000	What is the measured gas concentration of more the test gas? show less	N/A
PX810301_SingleBreath_CarbonMonoxide_DiffusingCapacity_Observed_Drift
	PX810301080000	Is significant drift observed over the time more scale of the test (~30 sec)? show less	N/A
PX810301_SingleBreath_CarbonMonoxide_DiffusingCapacity_Quality_Accuracy
	PX810301210100	Within the last 3 months, was the accuracy more of the measured gas readings assessed? show less	N/A
PX810301_SingleBreath_CarbonMonoxide_DiffusingCapacity_Quality_AccuracyDate
	PX810301210200	If no, what is today's date (test date)?	Variable Mapping
PX810301_SingleBreath_CarbonMonoxide_DiffusingCapacity_Quality_Calibration
	PX810301200000	Was the calibration test performed with a more 'standard subject' (biological control) or simulator? show less	N/A
PX810301_SingleBreath_CarbonMonoxide_DiffusingCapacity_Quality_Leaks
	PX810301180000	Within the last week, was the device tested more to be leak-free? show less	N/A
PX810301_SingleBreath_CarbonMonoxide_DiffusingCapacity_Quality_VolumeCalibration
	PX810301190000	Was the volume calibration test with the 3L more syringe performed? show less	N/A
PX810301_SingleBreath_CarbonMonoxide_DiffusingCapacity_ReadingStability_CO
	PX810301090000	Is the reading stable +/- 0.001% absolute for CO?	N/A
PX810301_SingleBreath_CarbonMonoxide_DiffusingCapacity_ReadingStability_Tracer
	PX810301100000	Is the reading stable +/- 0.5% of the full more scale reading for the tracer gas? show less	N/A
PX810301_SingleBreath_CarbonMonoxide_DiffusingCapacity_Results_Carboxyhemoglobin
	PX810301430000	Are carboxyhemoglobin levels < 2%? If not, more needs to be considered in interpretation show less	N/A
PX810301_SingleBreath_CarbonMonoxide_DiffusingCapacity_Standardization
	PX810301230000	Did the subject breathe supplemental oxygen more for 10 min prior to this test? show less	N/A
PX810301_SingleBreath_CarbonMonoxide_DiffusingCapacity_Standardization_Broncodilator
	PX810301330000	Was a bronchodilator used?	N/A
PX810301_SingleBreath_CarbonMonoxide_DiffusingCapacity_Standardization_Exercise
	PX810301240100	Was the subject involved in any exercise more prior to this test? show less	N/A
PX810301_SingleBreath_CarbonMonoxide_DiffusingCapacity_Standardization_ExerciseIntensity
	PX810301240200	If so, please describe the intensity level more of the exercise. show less	N/A
PX810301_SingleBreath_CarbonMonoxide_DiffusingCapacity_Standardization_LastCigarette
	PX810301270000	What time did the subject smoke his/her last more cigarette? show less	Variable Mapping
PX810301_SingleBreath_CarbonMonoxide_DiffusingCapacity_Standardization_SampleGasVolume
	PX810301290000	Is the sample gas volume collected between more 0.5-1.0L? show less	N/A
PX810301_SingleBreath_CarbonMonoxide_DiffusingCapacity_Standardization_SubjectDemonstration
	PX810301260000	Has a demonstration of the manuevers more involved in the test and instructions been provided to the subject? show less	N/A
PX810301_SingleBreath_CarbonMonoxide_DiffusingCapacity_Standardization_Supine
	PX810301250100	Was the subject in a supine position prior more to this test? show less	N/A
PX810301_SingleBreath_CarbonMonoxide_DiffusingCapacity_Standardization_SupineDuration
	PX810301250200	If so, please provide the duration of the more patient in the supine position? show less	N/A
PX810301_SingleBreath_CarbonMonoxide_DiffusingCapacity_Standardization_TotalExhalation
	PX810301280100	What length of time did the subject need for more total exhalation? show less	N/A
PX810301_SingleBreath_CarbonMonoxide_DiffusingCapacity_Standardization_TotalExhalationPlus
	PX810301280200	If total exhalation time > 4sec, please note more the expiratory time in seconds show less	N/A
PX810301_SingleBreath_CarbonMonoxide_DiffusingCapacity_Standardization_TracerType
	PX810301300100	What type of tracer gas was used?	N/A
PX810301_SingleBreath_CarbonMonoxide_DiffusingCapacity_Standardization_TracerTypeOther
	PX810301300200	What type of tracer gas was used? Other	N/A
PX810301_SingleBreath_CarbonMonoxide_DiffusingCapacity_Subject_Age
	PX810301390000	What is the age of the subject?	Variable Mapping
PX810301_SingleBreath_CarbonMonoxide_DiffusingCapacity_Subject_Height
	PX810301410000	What is the height of the subject?	Variable Mapping
PX810301_SingleBreath_CarbonMonoxide_DiffusingCapacity_Subject_Oad
	PX810301320100	Does the subject have obstructive airway disease?	N/A
PX810301_SingleBreath_CarbonMonoxide_DiffusingCapacity_Subject_OadRest
	PX810301320200	If so, were at least 10 minutes allowed more between tests? show less	N/A
PX810301_SingleBreath_CarbonMonoxide_DiffusingCapacity_Subject_Race
	PX810301420000	What racial/ethnic group does the subject more identify with? show less	Variable Mapping
PX810301_SingleBreath_CarbonMonoxide_DiffusingCapacity_Subject_Rest
	PX810301340000	Were at least 4 minutes allowed between tests?	N/A
PX810301_SingleBreath_CarbonMonoxide_DiffusingCapacity_Subject_Seated
	PX810301350000	Did the subject remain seated during that more interval? show less	N/A
PX810301_SingleBreath_CarbonMonoxide_DiffusingCapacity_Subject_Sex
	PX810301400000	What is the sex of the subject?	Variable Mapping
PX810301_SingleBreath_CarbonMonoxide_DiffusingCapacity_TestGas
	PX810301010100	Which of the following best describes the more source of test gas? show less	N/A
PX810301_SingleBreath_CarbonMonoxide_DiffusingCapacity_TestGasOther
	PX810301010200	Which of the following best describes the more source of test gas? Other show less	N/A
PX810301_SingleBreath_CarbonMonoxide_DiffusingCapacity_Testing_NewTest
	PX810301220000	Was the device tared to zero after the last test?	N/A
PX810301_SingleBreath_CarbonMonoxide_DiffusingCapacity_Timing_AutomatedComputation
	PX810301140100	Does the timing equipment rely on automated more data computation? show less	N/A
PX810301_SingleBreath_CarbonMonoxide_DiffusingCapacity_Timing_AutomatedComputationAccuracy
	PX810301140200	If so, how accurate is the breath-hold time more computation? show less	N/A
PX810301_SingleBreath_CarbonMonoxide_DiffusingCapacity_Zero_Measurement
	PX810301050000	What is the measured gas concentration at zero?	N/A

SCD Cardiovascular, Pulmonary, and Renal

Measure Name

Lung Function - Diffusion Capacity

Release Date

July 30, 2015

Definition

Clinical assessment to determine the capacity of an individual’s lung to exchange gases (e.g., oxygen and carbon dioxide) across the alveolar-capillary interface.

Purpose

This measure is used to assess the structural and functional properties of the lung and can detect and quantify symptoms associated with conditions that impact the lung, such as sickle cell disease, cystic fibrosis, and obstructive airways disease.

Keywords

Lung function, lung volume, lung physiology, diffusion capacity, D_LCO, functional residual capacity, FRC, sickle cell disease, SCD, emphysema, Cystic fibrosis, CF, asbestosis, lupus, arthritis, smoking, sarcoidosis, carbon monoxide, obstructive airway disease, Pulmonary, asthma, sleep apnea, breathing, sickle cell disease, SCD, "Cardiovascular, Pulmonary, and Renal"

Measure Protocols

Protocol ID	Protocol Name
810301	Lung Function - Diffusion Capacity

Publications

There are no publications listed for this protocol.

Mapping for PX810301_SingleBreath_CarbonMonoxide_DiffusingCapacity_Quality_AccuracyDate

dbGAP Study	dbGAP Variable	dbGAP Variable Description
CARDIA Cohort	phv00119634	DATE OF EXAM 2
CARDIA Cohort	phv00117591	DATE OF EXAM 4
CARDIA Cohort	phv00117590	DATE OF EXAM 3
CARDIA Cohort	phv00117589	DATE OF EXAM 2
CARDIA Cohort	phv00116541	DATE OF EXAM
CARDIA Cohort	phv00116389	DATE OF EXAM 3
CARDIA Cohort	phv00116388	DATE OF EXAM 2
CARDIA Cohort	phv00115318	DATE OF EXAM
CARDIA Cohort	phv00115117	DATE OF EXAM 2
CARDIA Cohort	phv00118300	DATE OF EXAM
CARDIA Cohort	phv00119257	DATE OF EXAM
CARDIA Cohort	phv00119628	DATE OF EXAM 5
CARDIA Cohort	phv00119635	DATE OF EXAM 3
CARDIA Cohort	phv00119636	DATE OF EXAM 4
CARDIA Cohort	phv00119727	DATE OF EXAM
CARDIA Cohort	phv00119780	DATE OF EXAM-FORM 5
CARDIA Cohort	phv00120011	DATE OF EXAM-FORM 9BCP
CARDIA Cohort	phv00120023	DATE OF EXAM-FORM 9
CARDIA Cohort	phv00120035	DATE OF EXAM-FORM 9TB
CARDIA Cohort	phv00120737	DATE OF EXAM 5
CARDIA Cohort	phv00120742	DATE OF EXAM 2
CARDIA Cohort	phv00120743	DATE OF EXAM 3
CARDIA Cohort	phv00120744	DATE OF EXAM 4
CARDIA Cohort	phv00120745	DATE OF EXAM 6
DCCT-EDIC Clinical Trial and Follow-up of Persons with Type 1 Diabetes	phv00032148	Date of examination
Framingham Cohort	phv00010826	What is the date today? (month, day, year)
Framingham Cohort	phv00072583	What is the date today? (month, day, year)
Framingham Cohort	phv00010807	What is the date today? (month, day, year)
Framingham Cohort	phv00010845	What is the date today? (month, day, year)
Framingham Cohort	phv00010864	What is the date today? (month, day, year)
Framingham Cohort	phv00010883	What is the date today? (month, day, year)
Framingham Cohort	phv00010902	What is the date today? (month, day, year)
Framingham Cohort	phv00010921	What is the date today? (month, day, year)
Framingham Cohort	phv00010940	What is the date today? (month, day, year)
Framingham Cohort	phv00010959	What is the date today? (month, day, year)
Framingham Cohort	phv00010978	What is the date today? (month, day, year)
Framingham Cohort	phv00010997	What is the date today? (month, day, year)
Framingham Cohort	phv00011018	What is the date today? (month, day, year)
Framingham Cohort	phv00011037	What is the date today? (month, day, year)
Framingham Cohort	phv00011056	What is the date today? (month, day, year)
Framingham Cohort	phv00072602	What is the date today? (month, day, year)
IMSGC Genome Wide Association Study of Multiple Sclerosis	phv00065554	Date of exam
The Genomics and Randomized Trials Network (GARNET) Vitamin Intervention Stroke Prevention (VISP) trial	phv00180273	What is today's date?
The Genomics and Randomized Trials Network (GARNET) Vitamin Intervention Stroke Prevention (VISP) trial	phv00180314	Date of exam
The Genomics and Randomized Trials Network (GARNET) Vitamin Intervention Stroke Prevention (VISP) trial	phv00180446	Today's date

Mapping for PX810301_SingleBreath_CarbonMonoxide_DiffusingCapacity_Standardization_LastCigarette

dbGAP Study	dbGAP Variable	dbGAP Variable Description
Atherosclerosis Risk in Communities (ARIC) Cohort	phv00207121	[Smoking]. When did you smoke your last cigarette? Q46 [Health/Medical History, exam 2]
Atherosclerosis Risk in Communities (ARIC) Cohort	phv00208999	[Smoking]. When did you smoke your last cigarette? Q28 [Personal History Form, exam 3]
Atherosclerosis Risk in Communities (ARIC) Cohort	phv00209074	[Smoking]. When did you smoke your last cigarette? Q9 [Personal History form, exam 4]
GENEVA: The Atherosclerosis Risk in Communities (ARIC) Study	phv00080714	When did you smoke last cigarette (visit 3)
GENEVA: The Atherosclerosis Risk in Communities (ARIC) Study	phv00080724	When did you smoke last cigarette (visit 4)

Mapping for PX810301_SingleBreath_CarbonMonoxide_DiffusingCapacity_Subject_Age

dbGAP Study	dbGAP Variable	dbGAP Variable Description
Alcohol Dependence GWAS in European- and African Americans	phv00164978	Age of participant
Asian Indian Diabetic Heart Study (AIDHS)	phv00190531	Age of participant
Autism post-mortem brain RNA-sequencing	phv00225016	Age of subject
Autosomal recessive PGM3 mutations cause a new Congenital Disorder of Glycosylation	phv00219151	Subject age
Autosomal recessive TPP2 mutations cause a new human immunodeficiency	phv00221155	Subject age
Characterization of Human Transcriptome by Computational and HTS Approaches	phv00224899	Subject age
Chromothripsis in Patient WHIM-09	phv00222544	Subject age
Ciliopathies Exome Sequencing Initiative	phv00165081	Age of subject
DCCT-EDIC Clinical Trial and Follow-up of Persons with Type 1 Diabetes	phv00033518	Patient's age (years) at baseline
DCCT-EDIC Clinical Trial and Follow-up of Persons with Type 1 Diabetes	phv00030755	Patient's age (form 001)
DCCT-EDIC Clinical Trial and Follow-up of Persons with Type 1 Diabetes	phv00030341	Patient's age
DCCT-EDIC Clinical Trial and Follow-up of Persons with Type 1 Diabetes	phv00030100	Patient's age (years) at baseline
DCCT-EDIC Clinical Trial and Follow-up of Persons with Type 1 Diabetes	phv00028592	Subject's age
DCCT-EDIC Clinical Trial and Follow-up of Persons with Type 1 Diabetes	phv00027984	Patient's age (form 001)
DNA Methylation Analysis of Prostate Cancer	phv00181135	Age of the subject
Drug Resistant Hypertension in African Americans' Exome	phv00164736	Age of Subject
Exome Sequencing of Esophageal Adenocarcinoma	phv00190856	Participant age
GDNF and Anxiety	phv00217717	Subject age
Genetic Measurement of Memory B-cell Recall Using Antibody Repertoire Sequencing	phv00195585	Subject age
Genetic Variation and Signatures of Natural Selection in Diverse Africans	phv00171015	Age of participant
Genetics of Lipid Lowering Drugs and Diet Network (GOLDN) Lipidomics Study	phv00202104	Age of participant
Genome-Wide Association Study of Neuroblastoma	phv00158906	Age of subject in days
Genomic Sequencing of Pediatric Rhabdoid Cancers	phv00171413	Participant age
Ghana Prostate Study	phv00226957	Subject age
HIV-1 Host Genetics Among Injection Drug Users	phv00167742	Reported age of participant
Immunosenescence: Immunity in the Young and Aged	phv00217652	Subject age
Joint Genome-Wide Gene Expression and GWAS Mapping in the MGS Dataset	phv00202327	Subject age
Melanoma Exome Sequencing	phv00226765	Subject age
Metagenomic Study of the Human Skin Microbiome Associated with Acne	phv00090398	Age of subject
NCI GWAS of Lung Cancer in Never Smokers	phv00201635	Subject age
NCI Non-Hodgkin Lymphoma GWAS	phv00225219	Subject age
NCI Non-Hodgkin Lymphoma GWAS	phv00225229	Subject age
NEI Age-Related Eye Disease Study (AREDS) - Genetic Variation in Refractive Error Substudy	phv00164694	Age of participant
NHLBI GO-ESP: Lung Cohorts Exome Sequencing Project (Asthma)	phv00181857	Age of participant at baseline
NINDS Parkinson's Disease	phv00024004	Age of subject
NINDS Parkinson's Disease	phv00023938	Age of subject
PAGE: Epidemiologic Architecture for Genes Linked to Environment (EAGLE) - BioVU Cancer Project	phv00196393	Age of participant
POLYGEN	phv00160480	Age of participant
POPRES: Population Reference Sample	phv00066601	Age of Subject
Responses to Varicella Zoster Virus Vaccination	phv00221180	Subject age
Sensitivity to the subjective effects of amphetamine	phv00221226	Age of participant
Sequence Analysis of Mutations and Translocations Across Breast Cancer Subtypes	phv00167356	Participant's age
Small Intestine Neuroendocrine Tumors (Carcinoid Tumors)	phv00190467	Participant's age [NR - not registrated]
Somatic Mutations in Variant and IGHV4-34 Expressing Hairy Cell Leukemia	phv00195930	Subject age
The Human Gut Microbiome and Recurrent Abdominal Pain in Children	phv00091113	Age of Participant
The Mutational Landscape of Head and Neck Squamous Cell Carcinoma	phv00163063	Participant's age
The Placenta Harbors a Unique Microbiome	phv00201428	Subject Age
VESPA: Genome Wide Study of Vancomycin	phv00225884	Age of participant
Whole Exome and Transcriptome Sequencing in Sporadic ALS	phv00201704	Subject age
Whole Exome Sequencing of Diffuse Large B-Cell Lymphoma	phv00165115	Participant's age

Mapping for PX810301_SingleBreath_CarbonMonoxide_DiffusingCapacity_Subject_Height

dbGAP Study	dbGAP Variable	dbGAP Variable Description
CARDIA Cohort	phv00116480	PATIENT DATA: HEIGHT (CM)
Columbia University Study of Caribbean Hispanics and Late Onset Alzheimer's disease	phv00180593	Height of subject
CPTAC Proteogenomic Confirmatory Study	phv00225400	Provide the height of the participant in centimeters.
DCCT-EDIC Clinical Trial and Follow-up of Persons with Type 1 Diabetes	phv00029374	Patient's height
DCCT-EDIC Clinical Trial and Follow-up of Persons with Type 1 Diabetes	phv00034113	Patient's height (cm)
DCCT-EDIC Clinical Trial and Follow-up of Persons with Type 1 Diabetes	phv00030689	Patient's height (cm) at baseline
DCCT-EDIC Clinical Trial and Follow-up of Persons with Type 1 Diabetes	phv00030103	Patient's height (cm) at baseline
DCCT-EDIC Clinical Trial and Follow-up of Persons with Type 1 Diabetes	phv00027262	Patient's height
eMERGE Genome-Wide Association Studies of Obesity	phv00163599	Height of subject.
eMERGE Genome-Wide Association Studies of Obesity (Metabochip)	phv00163770	Height of subject.
Genetic Variation and Signatures of Natural Selection in Diverse Africans	phv00171914	Height of participant
Genomic Wide Scans for Female Osteoporosis Genes	phv00161536	Height of study subject.
Jackson Heart Study (JHS) Cohort	phv00181213	Standing height in centimeters at first participant visit
NHLBI GO-ESP: Lung Cohorts Exome Sequencing Project (Asthma)	phv00181864	Height of participant at baseline
POLYGEN	phv00160481	Height of participant
Sensitivity to the subjective effects of amphetamine	phv00221231	Height of participant
Sequencing of Targeted Genomic Regions Associated with Smoking	phv00217970	Participant height in inches
The CARDIA-GENEVA Study	phv00129521	Participant's height, CM at Exam 1

Mapping for PX810301_SingleBreath_CarbonMonoxide_DiffusingCapacity_Subject_Race

dbGAP Study	dbGAP Variable	dbGAP Variable Description
A Family-Based Study of Genes and Environment in Young-Onset Breast Cancer	phv00196063	Self-identified race/ethnicity
A Multiethnic GWAS of Prostate Cancer	phv00142486	Self reported race/ethnicity
A Multiethnic GWAS of Prostate Cancer	phv00142465	Self reported race/ethnicity
A Multiethnic GWAS of Prostate Cancer	phv00124440	Self reported race/ethnicity
ADGC Genome Wide Association Study	phv00171928	Self-reported race of participant
Cholesterol and Pharmacogenetics (CAP) Study	phv00167791	Self-reported ethnicity (>=3 of 4 grandparents)
CIDR: Collaborative Study on the Genetics of Alcoholism (COGA)	phv00044650	Self-reported ethnicity
CIDR: NGRC Parkinson's Disease Study	phv00075998	Self report of ethnicity, per NIH classification.
CIDR: NGRC Parkinson's Disease Study	phv00075999	Self report of race, per NIH classification.
Copy Number Variation in Congenital Kidney Malformations	phv00174499	Self-identified ethnicity of participant
Epi4K: Gene Discovery in 4,000 Epilepsy Genomes: Genetic Analyses in Epileptic Encephalopathies	phv00195522	Self-declared ethnicity of participant
Epi4K: Gene Discovery in 4,000 Epilepsy Genomes: Genetic Analyses in Epileptic Encephalopathies	phv00201602	Self-declared ethnicity of participant
Framingham Cohort	phv00182405	Self report race
Genes and Blood Clotting Study (GABC)	phv00124355	Self reported ethnicity
Genes and Blood Clotting Study (GABC)	phv00124357	Self reported description of ethnicity
Genetic Discovery and Application in a Clinical Setting: Continuing a Partnership (eMERGE Phase II)	phv00252023	Self reported race
Genetic Predictors of Adverse Radiotherapy Effects (Gene-PARE)	phv00202678	Self-reported race/ethnicity of participant [Black, Asian, Caucasian, Hispanic]
GENEVA Genetics of Early Onset Stroke (GEOS) Study	phv00111931	Participant's self-reported ethnicity
GENEVA Genetics of Early Onset Stroke (GEOS) Study	phv00111928	Self-reported race
Genome-Wide Association Study of Schizophrenia	phv00034929	Self-identified ethnic ancestry
Genome-Wide Association Study of Schizophrenia	phv00020115	Self-identified ethnic ancestry
Genomic Predictors of Combat Stress Vulnerability and Resilience	phv00222715	Self Reported race of participant
Genomic Predictors of Combat Stress Vulnerability and Resilience	phv00222716	Self Reported ethnicity of participant
HIV-1 Host Genetics Among Injection Drug Users	phv00167741	Self-reported ancestry of participant
IgA Nephropathy GWAS (IGANGWAS)	phv00218100	Self-identified ethnicity of participant
IgA Nephropathy GWAS (IGANGWAS)	phv00164713	Self-identified ethnicity of participant
Jackson Heart Study (JHS) Cohort	phv00181206	Self report race
Multiethnic Cohort (MEC) Breast Cancer Genetics	phv00173160	Self reported race/ethnicity
National Children's Study Vanguard Study Formative Research Study (NCS)	phv00196031	Self-reported subject race
National Children's Study Vanguard Study Formative Research Study (NCS)	phv00196030	Self-reported subject ethnicity
NHGRI ClinSeq	phv00252432	Self-reported race of subject
NHGRI ClinSeq	phv00252433	Self-reported ethnicity of subject
NHLBI GO-ESP: Heart Cohorts Exome Sequencing Project (CHS)	phv00181176	Self report race
NHLBI GO-ESP: Heart Cohorts Exome Sequencing Project (ISGS)	phv00179586	Self reported Race
NHLBI GO-ESP: Heart Cohorts Exome Sequencing Project (ISGS)	phv00179585	Self reported Ethnicity
NHLBI GO-ESP: Heart Cohorts Exome Sequencing Project (MESA)	phv00178025	Self report race
NHLBI GO-ESP: Heart Cohorts Exome Sequencing Project (SWISS)	phv00174110	SELF REPORTED RACE OF PARTICIPANT
NHLBI GO-ESP: Women's Health Initiative Exome Sequencing Project (WHI) - WHISP	phv00161366	SELF REPORTED RACE OF PARTICIPANT
NIDCR Sjogren's International Collaborative Clinical Alliance (SICCA)	phv00226851	Self-reported ethnicity of participant
NIDDK IBD Genetics Consortium Ulcerative Colitis Genome-Wide Association Study	phv00162978	Race (self-report)
NIDDK IBDGC Crohn's Disease Genome-Wide Association Study	phv00057993	Race (self-report)
NINDS Stroke Genetics Network (SiGN)	phv00190675	Self reported ethnicity
NINDS Stroke Genetics Network (SiGN)	phv00190674	Self reported race
Resource for Genetic Epidemiology Research on Aging (GERA)	phv00196837	Self-reported race.
Sensitivity to the subjective effects of amphetamine	phv00221229	Self reported ethnicity participant
Sensitivity to the subjective effects of amphetamine	phv00221230	Self reported race of participant
Sequencing of Targeted Genomic Regions Associated with Smoking	phv00217968	Participant's self-identified race
Study of Addiction: Genetics and Environment (SAGE)	phv00022893	Participant's self-identified race
T1DGC: Genome-Wide Association Study in Type 1 Diabetes, 2008	phv00073466	Self-reported ethnicity
The Genetic Architecture of Smoking and Smoking Cessation	phv00162953	Participant's self-identified race
The Genetic Architecture of Smoking and Smoking Cessation	phv00162807	Participant's self-identified race
The Genomics and Randomized Trials Network (GARNET) Vitamin Intervention Stroke Prevention (VISP) trial	phv00159329	Patient's self-reported race category
The Sea Islands Genetic Network (SIGNET)	phv00163536	Self-reported race
UIC ACE Exome Sequencing Analysis	phv00200145	Array Ancestry and Self-Reported Race/Ethnicity as a single variable (array taking precedent)
UIC ACE Exome Sequencing Analysis	phv00200147	Reported Race
UIC ACE Exome Sequencing Analysis	phv00200146	Reported Ethnicity
Urethral Microbiome of Adolescent Males	phv00090535	Description of participant's self-reported race
Whole Exome Sequence of Hearing Loss Family	phv00252649	Ethnicity of participant
Whole Genome Association Study of Bipolar Disorder	phv00016943	Cover race. Self-reported race. DIGS4
Whole Genome Association Study of Bipolar Disorder	phv00013850	Subject's self-reported race. DIGS2
Whole-genome sequencing in multiplex epilepsy families	phv00196482	Self-declared ethnicity of participant

Mapping for PX810301_SingleBreath_CarbonMonoxide_DiffusingCapacity_Subject_Sex

dbGAP Study	dbGAP Variable	dbGAP Variable Description
A Genome-Wide Association Study of Peripheral Arterial Disease	phv00076111	Gender of participant
A Novel Recurrent Mutation in MITF Predisposes to Familial and Sporadic Melanoma	phv00164876	Gender of participant
Abundant Quantitative Trait Loci Exist for DNA Methylation and Gene Expression in Human Brain	phv00121765	Gender of subject
Acquired Copy Number Alterations in Adult Acute Myeloid Leukemia Genomes	phv00076146	Gender of participant
ADGC Genome Wide Association Study	phv00171927	Gender of participant
African American Breast Cancer GWAS	phv00226032	Gender of participant
Alcohol Dependence GWAS in European- and African Americans	phv00164977	Gender of participant
AMD-MMAP Cohort Study: A Joint Genome Wide Association Study	phv00073523	Gender of participant
Antigen Discovery in Melanoma	phv00253333	Sex of subject
ARRA Autism Sequencing Collaboration	phv00167339	Gender of participant
Asian Indian Diabetic Heart Study (AIDHS)	phv00190530	Gender of participant
Autopsy-Confirmed Parkinson Disease GWAS Consortium (APDGC)	phv00167765	Gender of participant
Autosomal recessive PGM3 mutations cause a new Congenital Disorder of Glycosylation	phv00219152	Gender of participant
Autosomal recessive TPP2 mutations cause a new human immunodeficiency	phv00221156	Gender of participant
B and T Cell Determinants of Influenza Vaccine Responses in the Elderly	phv00196119	Gender of participant
Benign Ethnic Neutropenia/Leukopenia (BEN) in African-Americans	phv00173359	Sex of participant
Biology and Molecular Analysis of Human Hematopoiesis Genetics	phv00168002	Gender of participant
Bladder Cancer Clinical Cohorts	phv00202613	Gender of participant
BrainCloud: Data from Human Postmortem Brain Across the Lifespan	phv00163196	Gender of subject
Breakpoint Detection Using Long Insert Whole Genome Sequencing	phv00193968	Gender of participant
Breast Cancer Study	phv00220928	Gender of participant [Female]
Building on GWAS for NHLBI-Diseases : the U.S. CHARGE Consortium (CHARGE-S): ARIC	phv00217501	Gender of participant
Building on GWAS for NHLBI-Diseases : the U.S. CHARGE Consortium (CHARGE-S): ARIC	phv00217516	Gender of participant
Building on GWAS for NHLBI-Diseases : the U.S. CHARGE Consortium (CHARGE-S): ARIC	phv00217489	Gender of participant
Bulgarian Schizophrenia Trio Sequencing Study	phv00197315	Gender of participant
BWH MS Genetic Collection	phv00173776	Gender of the participant
Cancer Genetic Markers of Susceptibility for Bladder Cancer (CGEMS Bladder)	phv00159001	Gender of participant [ FEMALE, MALE]
CCDG: Dental Caries and CL/P in Guatemala	phv00164848	Gender of participant.
CCHMC - eMERGE Data	phv00171343	Gender of participant
CD4+ cell transcriptional profiling by RNA sequencing	phv00193953	Gender of participant
Cebu Longitudinal Health and Nutrition Survey (CLHNS)	phv00173303	Gender of participant
CGEMS Breast Cancer GWAS	phv00066640	Gender of participant [FEMALE, MALE]
CGEMS Prostate Cancer GWAS - Stage 1 - PLCO	phv00082617	Gender of participant
Characterization of a Metastatic Cervical Cancer Using NGS	phv00195732	Gender of participant
Characterization of Human Transcriptome by Computational and HTS Approaches	phv00224900	Gender of participant
Characterization of Pancreatic Adenocarcinoma Patients Using NGS	phv00179509	Gender of participant
Characterization of X Chromosome Inactivation by high-throughput sequencing	phv00219126	Gender of participant
Chinese Alternating Hemiplegia of Childhood (AHC) Disease Study	phv00195755	Gender of participant
CHOP Control CNV Study	phv00076212	Gender of participant
Chromothripsis in Patient WHIM-09	phv00222541	Gender of participant
CIDR Whole Exome Sequencing in Joubert Syndrome	phv00161522	Gender of participant
CIDR: NGRC Parkinson's Disease Study	phv00075993	Self reported male or female.
Ciliopathies Exome Sequencing Initiative	phv00165082	Gender of subject
CIP: Differential Response to Hydroxyurea and Incidence of Stroke in Sickle Cell Disease	phv00196901	Gender of participant
CIP: Obesity-Diabetes Familial Risk	phv00191155	Gender of participant
Clonal Evolution of Pre-Leukemic HSC Precedes Human AML	phv00173910	Gender of participant
Cohort-Based Genome-Wide Association Study of Glioma (GliomaScan)	phv00195374	Gender of participant [FEMALE, MALE]
Colon Cancer Clinical Cohorts	phv00224966	Gender of participant
Consanguinity and Rare Mutations Outside of MCCC Genes Underlie Non-Specific Phenotypes of MCC Deficiency	phv00202353	Gender of participant
Copy Number Variation in Congenital Kidney Malformations	phv00174498	Gender of participant
CPTAC Proteogenomic Confirmatory Study	phv00225292	Participant gender using the defined categories. [Male; Female; Unknown; Unspecified]
CPTAC Proteogenomic Confirmatory Study	phv00225344	Participant gender using the defined categories. [Male; Female; Unknown; Unspecified]
CSER-MedSeq	phv00252786	Gender of subject
Cutaneous Microbiome in Psoriasis (HMP Demonstration Study)	phv00090655	Gender of participant
DCCT-EDIC Clinical Trial and Follow-up of Persons with Type 1 Diabetes	phv00024957	Patient's gender
DCCT-EDIC Clinical Trial and Follow-up of Persons with Type 1 Diabetes	phv00025695	Patient's gender
DCCT-EDIC Clinical Trial and Follow-up of Persons with Type 1 Diabetes	phv00026039	Patient's gender
DCCT-EDIC Clinical Trial and Follow-up of Persons with Type 1 Diabetes	phv00027102	Subject's gender
DCCT-EDIC Clinical Trial and Follow-up of Persons with Type 1 Diabetes	phv00027796	Patient's gender (coded m or f)
DCCT-EDIC Clinical Trial and Follow-up of Persons with Type 1 Diabetes	phv00028718	Patient's gender (form 001)
DCCT-EDIC Clinical Trial and Follow-up of Persons with Type 1 Diabetes	phv00028966	Patient's gender
DCCT-EDIC Clinical Trial and Follow-up of Persons with Type 1 Diabetes	phv00029309	Patient's gender (from form 001)
DCCT-EDIC Clinical Trial and Follow-up of Persons with Type 1 Diabetes	phv00030102	Patient's gender (0=male,1=female)
DCCT-EDIC Clinical Trial and Follow-up of Persons with Type 1 Diabetes	phv00030340	Patient's gender
DCCT-EDIC Clinical Trial and Follow-up of Persons with Type 1 Diabetes	phv00030687	Patient's gender
DCCT-EDIC Clinical Trial and Follow-up of Persons with Type 1 Diabetes	phv00030750	Patient's gender (form 001)
DCCT-EDIC Clinical Trial and Follow-up of Persons with Type 1 Diabetes	phv00030936	Patient's gender (from form 001)
DCCT-EDIC Clinical Trial and Follow-up of Persons with Type 1 Diabetes	phv00034144	Patient's gender
DCEG Lung Cancer Study	phv00159402	Gender of participant [FEMALE, MALE]
DFCI Brown Lab CLL Sequencing Study	phv00253297	Gender of participant
DFCI Colorectal Cancer Cohorts	phv00201985	Gender of participant
Diabetes Prevention Program Genetics (DPPG)	phv00201854	Gender of participant
Discovery of Non-ETS Gene Fusions using RNA Sequencing	phv00142652	Gender of participant
DNA Methylation Analysis of Prostate Cancer	phv00181136	Gender of subject
Dobyns DBD	phv00167279	Gender of participant
Drug Resistant Hypertension in African Americans' Exome	phv00164734	Gender of participant
Effect of Crohn's Disease Risk Alleles on Enteric Microbiota	phv00090595	Gender of participant
eMERGE Genome-Wide Association Studies of Obesity	phv00163596	Gender of subject.
eMERGE Genome-Wide Association Studies of Obesity (Metabochip)	phv00163767	Gender of subject.
eMERGE Network Combined Dataset	phv00182445	Gender of participant
eMERGE Network Study of Resistant Hypertension	phv00163159	Gender of participant.
Epi4K: Gene Discovery in 4,000 Epilepsy Genomes: Genetic Analyses in Epileptic Encephalopathies	phv00195521	Self-declared gender of participant
Epi4K: Gene Discovery in 4,000 Epilepsy Genomes: Genetic Analyses in Epileptic Encephalopathies	phv00201601	Self-declared gender of participant
Epigenetic and Genetic Profiling in Lymphoma	phv00226818	Gender of participant
Epigenetic Marks as Peripheral Biomarkers of Autism	phv00191073	Gender of participant
Epigenetic Profiling of Human Colorectal Cancer	phv00161708	Gender of participant
Exome Chip Study of NIMH Controls	phv00192229	Gender of participant
Exome Sequencing in Schizophrenia Families	phv00201670	Gender of participant
Exome sequencing of a family with thrombocytopenia and leukemia	phv00224938	Gender of participant
Exome Sequencing of arPEO	phv00162961	Gender of Participant
Exome Sequencing of Esophageal Adenocarcinoma	phv00190857	Participant gender as Male or Female
Exome Sequencing of Pleuropulmonary Blastoma	phv00173412	Participant's gender as 'Male' or 'Female'
Familial Exome Sequencing in Rare Pediatric Phenotypes	phv00179539	Gender of participant
Foregut Microbiome in Development of Esophageal Adenocarcinoma	phv00090620	Gender of subject
Framingham Cohort	phv00177929	Participant gender
FusionSeq: Finding Fusions with Paired-End RNA-Seq	phv00156548	Gender of participant
GDNF and Anxiety	phv00217716	Gender of participant
GEI Studies - Psoriasis	phv00202295	Gender of participant
Geisinger eMERGE - Abdominal Aortic Aneurysm Project (AAAP)	phv00163633	Gender of subject.
Geisinger eMERGE - MyCode Project	phv00163391	Gender of subject.
GenADA/LONG/Imaging (Genetic Alzheimer's Disease Associations)	phv00081063	Reported gender of participant
Gene Mutation and Rescue in Congenital Diaphragmatic Hernia	phv00167961	Gender of participant
Genentech Lung Cancer Sequencing	phv00112391	Gender of participant
Genentech Whole Genome Sequencing of Four Hepatocellular Carcinoma Patients	phv00163921	Gender of participant
Genes and Blood Clotting Study (GABC)	phv00124352	Participant gender
Genetic Analysis of Hirschsprung Disease	phv00168116	Gender of participant
Genetic Associations in Idiopathic Talipes Equinovarus (GAIT)	phv00141836	Gender of participant
Genetic Basis of Pulmonary Non-tuberculous Mycobacterial Infections	phv00200422	Gender of participant
Genetic Basis of XMEN Disease	phv00160299	Gender of participant
Genetic Defects in Familial Renal Disorders	phv00167981	Gender of participant
Genetic Measurement of Memory B-cell Recall Using Antibody Repertoire Sequencing	phv00195584	Gender of participant
Genetic Modifiers of Huntington's Disease	phv00173894	Gender of participant
Genetic Variation and Signatures of Natural Selection in Diverse Africans	phv00171014	Gender of participant
Genetic Variation and Signatures of Natural Selection in Diverse Africans	phv00171913	Gender of participant
Genetics of High HDL Cholesterol	phv00171948	Gender of participant
Genetics of Human Developmental Brain Disorders	phv00168106	Gender of participant
Genetics of Inherited Muscle Disease	phv00195631	Gender of participant
Genetics of Inherited Muscle Disease	phv00220881	Gender of participant
Genetics of Lipid Lowering Drugs and Diet Network (GOLDN) Lipidomics Study	phv00202103	Gender of participant
Genetics of Neuropsychiatric and Neurodevelopmental Disorders	phv00196236	Gender of participant
Genetics of Schizophrenia in an Ashkenazi Jewish Case-Control Cohort	phv00165039	Gender of participant
Genome Sequencing of Hepatocellular Carcinoma	phv00218134	Gender of participant
Genome Sequencing of Pancreatic Ductal Adenocarcinoma	phv00171496	Gender of participant
Genome Variations Among the Aboriginals in Malaysia	phv00195915	Gender of participant
Genome Wide Association Study in Familial Crohn's Disease	phv00190285	Gender of participant
Genome wide association study of 24 hour urine composition in the Nurses' Health Study, Nurses' Health Study II, and the Health Professionals Follow-Up Study	phv00165551	Gender of participant
Genome, Epigenome and RNA Sequences of MZ Twins Discordant for MS	phv00090329	Gender of participant
Genome-Wide Analysis of Chronic Lymphocytic Leukemia	phv00160276	Gender of participant
Genome-Wide Association Studies in Upper Gastrointestinal Cancers (Asian)	phv00159417	Gender of participant [FEMALE, MALE]
Genome-Wide Association Study of Amyotrophic Lateral Sclerosis in Finland	phv00158892	Gender of participant
Genome-Wide Association Study of Beh+ºet's Disease (Turkish)	phv00124464	Subject gender
Genome-Wide Association Study of Celiac Disease	phv00091144	Gender of Participant
Genome-wide Association Study of Myasthenia Gravis	phv00200998	Gender of participant
Genome-Wide Association Study of Neuroblastoma	phv00158908	Gender of the subject [Female, Male, Unknown]
Genomic Analysis of Pediatric Low Grade Gliomas	phv00190510	Gender of participant
Genomic Characterization of Meningiomas	phv00174205	Gender of participant
Genomic Origins and Admixture in Latinos (GOAL)	phv00202272	Gender of participant
Genomic Predictors of Combat Stress Vulnerability and Resilience	phv00222718	Gender of participant
Genomic Sequencing of Cervical Cancers	phv00182022	Gender of participant
Genomic Sequencing of Pediatric Rhabdoid Cancers	phv00171414	Participant gender as male or female [Male, Female]
Genomic Sequencing of Pediatric Rhabdomyosarcoma	phv00201888	Patient gender
Genomic Sequencing of Solitary Fibrous Tumors	phv00179053	Gender of participant
Genotyping 400 Samples from the NIGMS Human Variation Panels	phv00076466	Gender of participant
Genotyping NIGMS CEPH Samples from the United States, Venezuela, and France	phv00158856	Gender of participant
Genotyping NIGMS Chromosomal Aberration and Inherited Disorder Samples	phv00110716	Gender of participant
Ghana Prostate Study	phv00226956	Gender of participant
GWAS for Genetic Determinants of Bone Fragility	phv00065502	Gender of participant
GWAS in Fibrosing Interstitial Lung Disease	phv00201842	Gender of participant
GWAS of Breast Cancer in the African Diaspora	phv00172015	Gender of participant
GWAS of Familial Lung Cancer	phv00192256	Gender of participant
GWAS of Lung Cancer Susceptibility in Never-Smoking Women in Asia	phv00200111	Gender of participant [FEMALE, MALE]
GWAS on Cataract and HDL in the PMRP	phv00071870	Gender of participant
GWAS on Cataract and HDL in the PMRP	phv00077312	Gender of participant
Health and Retirement Study (HRS)	phv00167516	Gender of respondent
HeLa S3 (CCL-2.2) HiC Sequencing	phv00196373	Gender of participant [F]
High Density SNP Association Analysis of Lung Cancer	phv00201874	Gender of participant [Male, Female]
HIV-Resistant People with Hemophilia	phv00165018	Gender of participant
Human Autism Genetics and Activity Dependent Gene Activation	phv00226789	Gender of subject
Human Gut Microbiome in Amish Obesity	phv00090513	Gender of participant
Hypertriglyceridemia Study in Mexicans	phv00190652	Gender of participant
ICPCG Genome Wide Association Study of Familial Prostate Cancer	phv00201571	Gender of participant
Identification of Genes Involved in Familial Coronary Artery Disease	phv00171554	Gender of participant
Identification of Recurrent SMO and BRAF Mutations in Ameloblastomas	phv00201612	Sex of subject
IgA Nephropathy GWAS (IGANGWAS)	phv00218099	Gender of participant
IgA Nephropathy GWAS (IGANGWAS)	phv00164712	Gender of participant
Immunosenescence: Immunity in the Young and Aged	phv00217650	Gender of participant
Indianapolis-Ibadan, Nigeria Comparative Epidemiological Study of Dementia	phv00161465	Gender of subject
Integration of Genomics and Transcriptomics in unselected Twins and in Major Depression	phv00171371	Gender of participant
IPM BioBank GWAS	phv00162679	Gender of subject
Ischemic Stroke Genetics Study (ISGS)	phv00024265	Gender of the subject
Ischemic Stroke Genetics Study (ISGS)	phv00034499	Gender of participant (male or female)
Italian PBC Study	phv00168044	Gender of participant
Jackson Heart Study (JHS) Cohort	phv00125546	GENDER OF PARTICIPANT (M,F) Q18
Jackson Heart Study (JHS) Cohort	phv00125635	GENDER OF PARTICIPANT (M,F) Q18
Jackson Heart Study (JHS) Cohort	phv00125724	GENDER OF PARTICIPANT (M,F) Q18
Jackson Heart Study (JHS) Cohort	phv00125811	GENDER OF PARTICIPANT (M,F) Q18
Jackson Heart Study (JHS) Cohort	phv00126012	Gender of participant
Jackson Heart Study (JHS) Cohort	phv00127524	4: Participant's gender
Jackson Heart Study (JHS) Cohort	phv00172142	Gender of participant
Joint Genome-Wide Gene Expression and GWAS Mapping in the MGS Dataset	phv00202325	Gender of participant
L1-seq and genome-wide SNP genotyping in a multiethnic Asian population	phv00201446	Gender of participant
Longitudinal Genome-Wide Analysis of Patients with Chronic Lymphocytic Leukemia	phv00218111	Gender of participant
Megabase-scale Haplotyped Genomic Analysis of Normal and Cancer Genomes	phv00225801	Gender of participant
Melanoma Exome Sequencing	phv00226764	Gender of participant
Melanoma Genome Sequencing Project	phv00167383	Gender of patient [Male, Female]
Metabolism and Genetics of Hypobetalipoproteinemia	phv00174227	Gender of participant
Metagenomic Study of the Human Skin Microbiome Associated with Acne	phv00090394	Gender of participant
Minnesota Center for Twin and Family Research (MCTFR)	phv00201962	Gender of participant
miRNA profiles in serum and CSF of Parkinson's and Alzheimer's patients	phv00201810	Gender of participant
MitoExome Sequencing of Mitochondrial OXPHOS Diseases (MGH)	phv00156596	Gender of participant
Molecular Defects in Pseudohypoparathyroidism or Related Disorders	phv00167913	Gender of participant
Molecular Genetic Analysis of Inherited Kidney Dysfunction	phv00167971	Gender of participant
Molecular Profiling of Cancer	phv00165136	Gender of participant
Multiethnic Cohort (MEC) Breast Cancer Genetics	phv00173161	Gender of participant
N.C. Clinical Genomic Evaluation by NextGen Exome Sequencing (NCGENES)	phv00222601	Gender of participant
NCI Genome-Wide Association Study of Renal Cell Carcinoma	phv00159249	Gender of participant
NCI GWAS of Lung Cancer in Never Smokers	phv00201633	Gender of participant
NCI GWAS of Renal Cell Carcinoma in African Americans	phv00226593	Gender of participant [MALE, FEMALE]
NCI Non-Hodgkin Lymphoma GWAS	phv00225228	Gender of participant [MALE, FEMALE]
NCI Non-Hodgkin Lymphoma GWAS	phv00225218	Gender of participant
NEI Ocular Hypertension Treatment Study (OHTS)	phv00160401	Gender of participant
Neurodevelopmental Genomics: Trajectories of Complex Phenotypes	phv00194003	Gender of participant as identified by survey of patient/patient's parent
Neurodevelopmental Genomics: Trajectories of Complex Phenotypes	phv00194909	Subject's gender
Next Generation Mendelian Genetics: Familial Hemophagocytic Lymphohistiocytosis	phv00174188	Gender of participant
NGS in Advanced Cancers	phv00195642	Gender of participant
NHGRI Tumor Sequencing Project (Lung Adenocarcinoma)	phv00071771	Gender of participant
NHLBI GO-ESP: Family Studies (Aortic Disease)	phv00179491	Gender of participant
NHLBI GO-ESP: Family Studies (Atypical Cystic Fibrosis)	phv00179565	Gender of participant
NHLBI GO-ESP: Family Studies (Dilated Cardiomyopathy)	phv00181166	Gender of participant
NHLBI GO-ESP: Family Studies (Familial Interstitial Pneumonia)	phv00182046	Gender of participant
NHLBI GO-ESP: Family Studies (Hematological Cancers)	phv00196142	Gender of participant
NHLBI GO-ESP: Family Studies (Mendelian Lipid Disorders)	phv00195790	Gender of participant
NHLBI GO-ESP: Family Studies: (Familial Atrial Fibrillation)	phv00181914	Gender of participant
NHLBI GO-ESP: Heart Cohorts Exome Sequencing Project (SWISS)	phv00174111	GENDER OF PARTICIPANT
NHLBI GO-ESP: Lung Cohorts Exome Sequencing Project (Asthma)	phv00181856	Gender of participant
NHLBI GO-ESP: Lung Cohorts Exome Sequencing Project (Cystic Fibrosis)	phv00159434	Gender of participant
NHLBI GO-ESP: Lung Cohorts Exome Sequencing Project (Cystic Fibrosis)	phv00159440	Gender of participant
NHLBI GO-ESP: Women's Health Initiative Exome Sequencing Project (WHI) - WHISP	phv00161367	GENDER OF PARTICIPANT
NIDCR Sjogren's International Collaborative Clinical Alliance (SICCA)	phv00226846	Gender of participant
NIDDK Gene discovery in FSGS	phv00202568	Gender of participant
NIDDK Gene discovery in VUR	phv00202545	Gender of participant
NIH Exome Sequencing of Familial Amyotrophic Lateral Sclerosis Project	phv00200477	Gender of participant
NIH Exome Sequencing of Familial Amyotrophic Lateral Sclerosis Project	phv00088181	Gender of participant
NIH Exome Sequencing of Familial Amyotrophic Lateral Sclerosis Project	phv00158872	Gender of participant
NINDS Parkinson's Disease	phv00023939	Gender of subject
NINDS Parkinson's Disease	phv00024005	Gender of subject
NINDS Parkinsonism Study	phv00000187	Gender of the subject
NINDS Repository Cerebrovascular Disease/Stroke Study	phv00024079	Gender of the subject
NINDS Repository Motor Neuron Disease/ALS Study	phv00020520	Gender of the subject
NINDS Repository Neurologically Normal Control Collection	phv00000225	Gender of the subject
Northwestern NUgene Project: Type 2 Diabetes	phv00158808	Gender of participant
OMRF SLEGEN GWAS Data from European-American Women with Lupus	phv00076097	Gender of subject
Oncogenomics of Malignant Peripheral Nerve Sheath Tumors	phv00217577	Gender of participant
Osteosarcoma Genome-wide Association Study	phv00200964	Gender of participant [FEMALE, MALE]
Osteosarcoma Genomics	phv00220907	Gender of patient
PAGE: Epidemiologic Architecture for Genes Linked to Environment (EAGLE) - BioVU Cancer Project	phv00196394	Gender of participant
Paired AML Epigenetics Study on Clonality	phv00202812	Gender of participant
Pancreatic Cancer Case-Control Association Study	phv00226238	Gender
Pancreatic Cancer Cohort and Case-Control Consortium (PanScan)	phv00076258	Gender of participant [MALE, FEMALE]
PGC: the PUWMa GWAS of ADHD	phv00159878	Gender of participant
PGRN-RIKEN: Rate Control Therapy in Patients with Atrial Fibrillation	phv00173383	Gender of participant
Pharmacogenomics of Anti-Platelet Intervention (PAPI) Study	phv00173925	Gender of participant
Pilocytic Astrocytoma in NF1	phv00174531	Gender of participant
POLYGEN	phv00160468	Gender of participant
POLYGEN	phv00160479	Gender of participant
Primary ER-positive Breast Cancer Treated with Neoadjuvant Letrozole	phv00222697	Gender of participant
Prostate Cancer Genome Sequencing Project	phv00167303	Gender of participant [Male, Female]
Rapid Whole Genome Sequencing for Genetic Disease Diagnosis in the NICU	phv00174357	Gender of participant
Resistance studies in Lung Cancer	phv00224917	Gender of participant
Responses to Varicella Zoster Virus Vaccination	phv00221179	Gender of participant
Retrotransposition in Colorectal Cancer	phv00173541	Gender of participant
RM Epigenomics Program - Broad_Alz_and_Age-Related	phv00191101	Gender of participant
RNA-Seq studies of Gene Expression in Cells and Networks in FI and ACC in Autism	phv00190495	Gender of participant
RNAseq analysis of posterior cingulate astrocytes in Alzheimer's disease	phv00201726	Gender of participant
San Francisco Bay Area Latina Breast Cancer Study	phv00226550	Gender of participant
Sensitivity to the subjective effects of amphetamine	phv00221225	Gender of participant
Sequence Analysis of Mutations and Translocations Across Breast Cancer Subtypes	phv00167357	Participant's gender as male or female [Male, Female]
Sequencing of Targeted Genomic Regions Associated with Smoking	phv00217965	Participant gender
Shanghai Breast Cancer Genetics Study (SBCGS)	phv00217898	Gender of participant [female, male]
Single Cell Analysis Program - Transcriptome (SCAP-T)	phv00219205	Gender of the subject
Skin Microbiome in Disease States: Atopic Dermatitis and Immunodeficiency	phv00090676	Gender of participant [Male; Female]
Small Intestine Neuroendocrine Tumors (Carcinoid Tumors)	phv00190468	Participant's gender as Male or Female
SNP Health Association Resource (SHARe) Asthma Resource Project (SHARP)	phv00070936	Gender of participant
SNP Health Association Resource (SHARe) Asthma Resource Project (SHARP)	phv00070997	Gender of participant
SNP Health Association Resource (SHARe) Asthma Resource Project (SHARP)	phv00071047	Gender of participant
SNP Health Association Resource (SHARe) Asthma Resource Project (SHARP)	phv00071105	Gender of participant
SNP Health Association Resource (SHARe) Asthma Resource Project (SHARP)	phv00071155	Gender of participant
SNP Health Association Resource (SHARe) Asthma Resource Project (SHARP)	phv00071213	Gender of participant
Somatic Mutations in Variant and IGHV4-34 Expressing Hairy Cell Leukemia	phv00195931	Gender of participant
Spectrum of Mutations in Myeloid Neoplasms	phv00202080	Gender of participant
Sporadic Amyotrophic Lateral Sclerosis (ALS): Sequencing Study	phv00252380	Biological gender of subject
STAMPEED: Northern Finland Birth Cohort 1966 (NFBC1966)	phv00129605	Gender of participant
Strabismus, CCDD and Other Anomalies	phv00167779	Gender of participant
Strong Activation of Retroviral LTRs in HCC	phv00225166	Gender of participant
Study of Adaptation to Hypoxia in Ethiopian Highlanders	phv00195533	Gender of participant
Sweden-Schizophrenia Population-Based Case-Control Exome Sequencing	phv00167461	Gender of participant
Targeted Sequencing of GWAS Loci in Cleft Lip and Palate	phv00201753	Gender of participant
The Detroit Neighborhood Health Study (DNHS)	phv00174401	Gender of participant.
The Gene Partnership (TGP) - eMERGE Data	phv00171962	Gender of Subject - as reported by participant
The Genetic Landscape of Mutations in Burkitt Lymphoma	phv00178124	Gender of participant
The Genomic Complexity of Primary Human Prostate Cancer	phv00154533	Gender of participant
The Human Gut Microbiome and Recurrent Abdominal Pain in Children	phv00091112	Gender of participant
The Human Virome and Febrile Illness in Children	phv00098405	Gender of participant
The Molecular Basis of Inherited Reproductive Disorders	phv00167992	Gender of participant
The Mutational Landscape of Head and Neck Squamous Cell Carcinoma	phv00163064	Participant's gender [Male, Female]
The Neonatal Microbiome and NEC	phv00091251	Sex of subject
The Neonatal Microbiome and NEC	phv00091258	Sex of subject
The Role of the Gut Microbiota in Ulcerative Colitis	phv00091161	Participant gender [Male or Female]
The UC San Diego Chronic Lymphocytic Leukemia (CLL) Study	phv00202243	Gender of participant
Treatment of Genetic Screening of Hypertriglyceridemia type I, III, and V - HTG Amsterdam	phv00171438	Gender of participant
Type 1 Diabetes Genetics Consortium (T1DGC): Copy Number Variant (CNV) Study	phv00226507	Gender of participant
Type 2 Diabetes in African Americans, GWAS and Exome Sequencing	phv00066340	Gender of participant has been confirmed with genotyping: 1 = Male, 2 = Female
Type 2 Diabetes in African Americans, GWAS and Exome Sequencing	phv00066354	Gender of participant has been confirmed with genotyping: 1 = Male, 2 = Female
Tyrosine Kinase Mutations in Endometrial Cancer	phv00221198	Gender of participant
University of Miami Study on Genetics of Autism and Related Disorders (AutismDisorders)	phv00171540	Gender of participant
University of Michigan Clinical Sequencing Exploratory Research (CSER)	phv00197132	Gender of participant
University of Washington CSF biomarker study for Parkinson disease	phv00225944	Gender of participant
Vanderbilt Genome-Electronic Records (VGER) Project: QRS Duration	phv00077277	Gender of participant
VESPA: Genome Wide Study of Vancomycin	phv00225885	Gender of participant
VitGene Generalized Vitiligo Genetics Study	phv00158991	Gender of participant
Whole Exome and Targeted Sequencing in Tourette Syndrome Multiplex Families	phv00163339	Gender of participant
Whole Exome and Transcriptome Sequencing in Sporadic ALS	phv00201705	Gender of participant
Whole Exome Sequence of Hearing Loss Family	phv00252647	Gender of participant
Whole Exome Sequencing for Colorectal Cancer	phv00163736	Gender of participant
Whole Exome Sequencing of Diffuse Large B-Cell Lymphoma	phv00165116	Participant's gender [Male or Female]
Whole Genome Association Twin Study of Myopia and Glaucoma Risk Factors	phv00066468	Gender of participant
Whole Genome Comparisons of Breast Cancers and their Xenotransplants	phv00195712	Subject's gender
Whole Genome Sequencing of Triple Negative Breast Cancer	phv00124471	Gender of participant
Whole Genome Sequencing of Two 22q11DS Trios	phv00222265	Gender of participant
Whole-Genome and Exome Sequencing in Clear-Cell Renal Cell Carcinoma	phv00168012	Gender of participant
Whole-genome sequencing in multiplex epilepsy families	phv00196481	Self-declared gender of participant
Whole-Genome Sequencing of Acute Myeloid Leukemia	phv00073670	Gender of participant
XPC and Non-XPC Cutaneous Squamous Cell Carcinoma Mutation Rate Study	phv00252611	Gender of participant