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Protocol - Lung Function - Lung Volume

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Description:

The American Thoracic Society (ATS) and the European Respiratory Society (ERS) Task Force recommendations for standardisation of the measurement of lung volume testing outline how to obtain measurement of functional residual capacity (FRC) using body plethysmography, nitrogen washout, helium dilution, and imaging techniques. In addition, this source contains details regarding the assessment of total lung capacity (TLC), vital capacity (VC), reserve volume (RV), expiratory reserve volume (ERV), and inspiratory capacity (IC).

These recommendations for standardization of the measurement of lung volume testing are part of a series of recommendations by the ATS/ERS Task Force for the standardization of lung function testing, which can be found on the ATS website at www.thoracic.org/statements/pulmonary-function.php. Detailed information regarding patient preparation is included in the general considerations document for lung function testing in this series.

Specific Instructions:

A comprehensive evaluation of lung function requires investigation of various aspects of the lung, such as lung volumes and diffusion capacity. Hence, the American Thoracic Society (ATS) and the European Respiratory Society (ERS) Task Force have published a series of documents regarding pulmonary function testing. The Sickle Cell Disease: Cardiovascular, Pulmonary, and Renal Working Group recommends researchers access the ATS website (www.thoracic.org/) to view other documents in this series that may apply to their area of research.

Additionally, although there are various methods to measure functional residual capacity (FRC), the Working Group views body plethysmography as the most accurate, particularly when airflow obstruction is a possible underlying condition.

Protocol:

Lung Function Testing: Measurement of Lung Volume

The American Thoracic Society (ATS) and the European Respiratory Society (ERS) Task Force recommendations for standardisation of the measurement of lung volumes can be found here as well as on the ATS website here.

Protocol Name from Source:

Availability:

Publicly available

Personnel and Training Required

Certified respiratory therapist

Equipment Needs

Equipment needed for the calculation of lung volumes are outlined in the American Thoracic Society (ATS) and the European Respiratory Society (ERS) Task Force recommendations for standardisation of the measurement of lung volumes can be found here as well as on the ATS website here.

Requirements
Requirement CategoryRequired
Major equipment Yes
Specialized training Yes
Specialized requirements for biospecimen collection No
Average time of greater than 15 minutes in an unaffected individual No
Mode of Administration

Clinical assessment

Life Stage:

Child, Adolescent, Adult, Senior, Pregnancy

Participants:

Individuals age 8 years old and older.

Selection Rationale

The Sickle Cell Disease Cardiovascular, Pulmonary, and Renal Working Group recommends the American Thoracic Society (ATS) and the European Respiratory Society (ERS) Task Force 2005 recommendations for standardisation of the measurement of lung volumes because this document integrates and consolidates the task force recommendations and the recommendations from various National Heart, Lung, and Blood Institute (NHLBI) workshops.

Language

English

Standards
StandardNameIDSource
Common Data Elements (CDE) Lung Forced Expiratory Volume 1 Test Value 2629105 CDE Browser
Human Phenotype Ontology Restrictive ventilatory defect HP:0002091 HPO
Derived Variables

None

Process and Review

Not applicable.

Source

Wanger, J., Clausen, J. L., Coates, A., Pedersen, O. F., Brusasco, V., Burgos, F., Casaburi, R., Crapo, R., Enright, P., van der Grinten, C. P. M., Gustafsson, P., Hankinson, J., Jensen, R., Johnson, D., MacIntyre, N., McKay, R., Miller, M. R., Navajas, D., Pellegrino, R., & Viegi, G. (2005). Standardisation of the measurement of lung volumes. European Respiratory Journal, 26, 511-522. doi: 10.1183/09031936.05.00035005

General References

Arteta, M., Campbell, A., Nouraie, M., Rana, S., Onyekwere, O. C., Ensing, G., Sable, C., Dham, N., Darbari, D., Luchtman-Jones, L., Kato, G. J., Gladwin, M. T., Castro, O. L., Minniti, C. P., & Gordeuk, V. R. (2014). Abnormal pulmonary function and associated risk factors in children and adolescents with sickle cell anemia. Journal of Pediatric Hematology/Oncology, 36(3), 185-189.

Lunt, A., Desai, S. R., Wells, A. U., Hansell, D. M., Mushemi, S., Melikian, N., Shah, A. M., Thein, S. L., & Greenough, A. (2014). Pulmonary function, CT and echocardiographic abnormalities in sickle cell disease, Thorax 69(8), 746-751.

Protocol ID:

810401

Variables:
Export Variables
Variable Name Variable IDVariable DescriptiondbGaP Mapping
PX810401_Standardisation_LungVolumeMeasurement_BodyPleth_Calibration
PX810401390105 If body plethysmography method is used to more
measure FRC, was the mouth pressure transducer and plethysmograph signal calibrated within the past 24 hours? show less
N/A
PX810401_Standardisation_LungVolumeMeasurement_BodyPleth_Calibration_Controls
PX810401390106 If body plethysmography method is used to more
measure FRC, at least once a month or whenever plethysmographic errors are suspected, was the plethysmograph recalibrated with two reference subjects (biological controls)? show less
N/A
PX810401_Standardisation_LungVolumeMeasurement_BodyPleth_ConstantPressure
PX810401390301 If volume-displacement plethysmograph, what more
is the volume within the constant-pressure chambler? show less
N/A
PX810401_Standardisation_LungVolumeMeasurement_BodyPleth_ConstantPressure_Airflow
PX810401390101 If flow plethysmograph, what is the airflow more
rate in and out of the constant-pressure chamber? show less
N/A
PX810401_Standardisation_LungVolumeMeasurement_BodyPleth_ConstantVolume
PX810401390201 If variable-pressure plethysmograph, what is more
the pressure within the constant-volume chamber? show less
N/A
PX810401_Standardisation_LungVolumeMeasurement_BodyPleth_Frc
PX810401390104 If body plethysmography method is used to more
measure FRC, what is the reported FRC value? show less
N/A
PX810401_Standardisation_LungVolumeMeasurement_BodyPleth_Measurement_Technique
PX810401390103 If body plethysmography method is used to more
measure FRC, does the measurement technique adhere to the following steps? 1) Equipment should be turned on and allowed an adequate time to warm up; 2) Equipment is set up for testing, including calibration, according to manufacturer's instructions; 3) Equipment is adjusted so that the patient can sit comfortably in the chamber and reach the mouthpiece without having to flex or extend the neck; 4) Patient is seated comfortably with no need to remove dentures; 5) The plethysmograph door is closed and time is allowed for the thermal transients to stabilize and the patient to relax; 6) The patient is instructed to attach to the mouthpiece and breathe quietly until a stable end-expiratory level is achieved (usually 3-10 tidal breaths); 7) When the patient is at or near FRC, the shutter is closed at end-expiration for ~2-3 seconds and the patient is instructed to perform a series of gentle pants (~+/- kPa) at a frequency between 0.5 and 1.0 Hertz; 8) A series of 3-5 technically satisfactory panting manuevers should be recorded; 9) For those unable to perform appropriate panting manuevers, an alternative is to perform a rapid inspiratory manuever against the closed shutter; 10) At least three FRC values that agree within 5% (i.e. difference between the highest and value divided by the mean <= 0.05) should be obtained and mean value reported show less
N/A
PX810401_Standardisation_LungVolumeMeasurement_BodyPleth_Transducer
PX810401390102 If body plethysmography method is used to more
measure FRC, is the transducer capable of measure mouth pressure greater than +/- 5kPa? show less
N/A
PX810401_Standardisation_LungVolumeMeasurement_BodyPleth_Type
PX810401390000 If body plethysmography method is used to more
measure FRC, which type of plethysmograph is used to track changes in thoracic volume? show less
N/A
PX810401_Standardisation_LungVolumeMeasurement_Current_BarometricPressure
PX810401150000 What is the current barometric pressure? Variable Mapping
PX810401_Standardisation_LungVolumeMeasurement_Current_Temperature
PX810401140000 What is the current ambient temperature? Variable Mapping
PX810401_Standardisation_LungVolumeMeasurement_Current_Time
PX810401160000 What is the current time? N/A
PX810401_Standardisation_LungVolumeMeasurement_Equipment_Closed_Circuit
PX810401230000 Since the previous subject, if a more
closed-circuit technique was used, were volume-based spirometers flushed with room air at least five times over the entire volume range? show less
N/A
PX810401_Standardisation_LungVolumeMeasurement_Equipment_OpenCircuit_Mouthpiece
PX810401250000 Since the previous subject, if an more
open-circuit technique was used, were volume- and flow-based spirometers used without inspiration from the measuring system had their outhpieces replaced/sterilized? show less
N/A
PX810401_Standardisation_LungVolumeMeasurement_Equipment_OpenCircuit_Replacement
PX810401240000 Since the previous subject, if an more
open-circuit technique was used and the subject only expires into the spirometer, was the portion of the circuit which rebreathing occurs properly decontaminated? show less
N/A
PX810401_Standardisation_LungVolumeMeasurement_Equipment_Reusable_Components
PX810401220000 Has reusable equipment (such as mouthpieces, more
breathing tubes, valves and manifolds or any other equipment showing visible condensation from expired air) been disinfected/sterilized? show less
N/A
PX810401_Standardisation_LungVolumeMeasurement_FirstMethod_Erv
PX810401370202 If first method, what is the reported value more
for the (technically satisfactory) expiratory reserve volume (ERV)? show less
N/A
PX810401_Standardisation_LungVolumeMeasurement_FirstMethod_Frc
PX810401370201 If first method, what is the reported value more
for the functional residual capacity (mean of technically satisfactory FRC measurements)? show less
N/A
PX810401_Standardisation_LungVolumeMeasurement_FirstMethod_Ivc
PX810401370203 If first method, what is the reported value more
for the (technically satisfactory) inspiratory vital capacity (IVC)? show less
N/A
PX810401_Standardisation_LungVolumeMeasurement_Helium_Analyzer_Flow
PX810401410900 If helium dilution method is used to measure more
FRC, does the helium analyzer allow a flow of >=200 mL/min? show less
N/A
PX810401_Standardisation_LungVolumeMeasurement_Helium_Analyzer_Range
PX810401410600 If helium dilution method is used to measure more
FRC, does the helium analyzer have a range of ~0-10% helium, a resolution of <= 0.01% helium over the entire range, and a 95% response time of <15seconds to a 2% step change in helium concentration? show less
N/A
PX810401_Standardisation_LungVolumeMeasurement_Helium_Analyzer_Stability
PX810401410700 If helium dilution method is used to measure more
FRC, is the meter stable with a drift of <= 0.02% for measurement periods up to 10 minutes? show less
N/A
PX810401_Standardisation_LungVolumeMeasurement_Helium_Analyzer_Type
PX810401410400 If helium dilution method is used to measure more
FRC, what type of analyzer is being used? show less
N/A
PX810401_Standardisation_LungVolumeMeasurement_Helium_Analyzer_TypeOther
PX810401410500 If helium dilution method is used to measure more
FRC, what type of analyzer is being used? Other show less
N/A
PX810401_Standardisation_LungVolumeMeasurement_Helium_CalibrationStep
PX810401410200 If helium dilution method is used to measure more
FRC, before measurements are taken, was enough 100% helium added to the system where the helium reading was ~10%? show less
N/A
PX810401_Standardisation_LungVolumeMeasurement_Helium_Calibration_Control
PX810401411800 If helium dilution method is used to measure more
FRC, was testing of biological controls performed at least once in the past month? show less
N/A
PX810401_Standardisation_LungVolumeMeasurement_Helium_CarbonDioxide
PX810401411000 If helium dilution method is used to measure more
FRC, is the breathing-circuit CO2 levels during testing below 0.5%? show less
N/A
PX810401_Standardisation_LungVolumeMeasurement_Helium_DeadSpace
PX810401411300 If helium dilution method is used to measure more
FRC, does the breathing valve and mouthpiece have a combined dead space <100mL? show less
N/A
PX810401_Standardisation_LungVolumeMeasurement_Helium_Flow
PX810401410300 If helium dilution method is used to measure more
FRC, does the device have a flow of ~50 L/min? show less
N/A
PX810401_Standardisation_LungVolumeMeasurement_Helium_Leak_Check
PX810401411600 If helium dilution method is used to measure more
FRC, for systems that can be pressurized, were leaks checked for at least once in the past 24 hours and/or after every tubing or canister changes? show less
N/A
PX810401_Standardisation_LungVolumeMeasurement_Helium_Measurement_Technique
PX810401411400 If helium dilution method is used to measure more
FRC, does the measurement technique adhere to the following steps? 1) Equipment is turned on and allowed an adequate warm-up time, with calibration as instructed by manufacturer; 2) The equipment should be set up for testing, including calibration, according to manufacturer's instructions; 3) Patient should be asked if he/she has a perforated eardrum (if so, earplug should be used); 4) Patient is seated comfortable with no need to remove dentures. The procedure is explained, emphasizing the need to avoid leaks around the mouthpiece during the washout and using a nose clip; 5) The patient breathes for ~30-60 seconds on the mouthpiece to become accustomed to the apparatus and to ensure a stable end-tidal expiratory level; 6) The patient is turned 'in' (i.e. connected to the test gas) at the end of a normal tidal expiration; 7) The patient is instructed to breathe regular tidal breathes; 8) The O2 flow is adjusted to compensate for O2 consumption (significant errors in the calculation of FRC can result in O2 consumption is not adequately accounted for); 9) The helium concentration is noted ever 15s; 10) Helium equilibration is considered to be complete when the change in helium concentration is <0.02% for 30 seconds. The test rarely exceeds 10 minutes, even in patients with severe gas-exchange abnormalities; 11) Once the helium equilibration is complete, the patient is turned 'out' (i.e. disconnected from the test gas) of the system; 12) At least one technically satisfactory measurement should be obtained. Due to extra costs and time in making multiple measurements, and the relatively good inter-day variability in adults, two or more measurements of FRC need to be made only when necessitated by clinical or research need. For younger children, it is recommeneded that at least two technically satisfactory measurements of FRC to be carried out. show less
N/A
PX810401_Standardisation_LungVolumeMeasurement_Helium_Oxygen_Recalibration
PX810401410800 If helium dilution method is used to measure more
FRC, for systems in which O2 concentration changes substantially, was the helium analyzer recalibrated over the range of O2 concentrations encountered? show less
N/A
PX810401_Standardisation_LungVolumeMeasurement_Helium_Quality_Control
PX810401411500 If helium dilution method is used to measure more
FRC, before the subject was tested, were the following items checked? Water level of water-sealed spirometer; status of all CO2 and water absorbers; operation of the circuit fan; baseline stability of helium and volume signals show less
N/A
PX810401_Standardisation_LungVolumeMeasurement_Helium_Spirometer_QualityControl
PX810401410100 If helium dilution method is used to measure more
FRC, is the capacity of the spirometer at least 7 liters and is the device equipped with a mixing fan, CO2 absorber, O2 and helium supply, a gas inlet and outlet, and a water vapour absorber in the line to the helium analyzer? show less
N/A
PX810401_Standardisation_LungVolumeMeasurement_Helium_Stability_Temperature
PX810401411700 If helium dilution method is used to measure more
FRC, was the stability (<0.02% drift in 10 min) and temperature of the helium meter checked at least once in the past week? show less
N/A
PX810401_Standardisation_LungVolumeMeasurement_Helium_Temperature
PX810401411100 If helium dilution method is used to measure more
FRC, what is the temperature of the gas in the breathing circuit? show less
N/A
PX810401_Standardisation_LungVolumeMeasurement_Helium_Temperature_Sensor
PX810401411200 If helium dilution method is used to measure more
FRC, does the temperature sensor have an accuracy of better than 0.5 degrees Celsius over the range of 12-30 degrees Celsius and have a 90% response time of <30 seconds to a 5 degree Celsius step change of temperature of the gas inside the breathing circuit? show less
N/A
PX810401_Standardisation_LungVolumeMeasurement_Imaging_Technique
PX810401420200 If the subject has limited ability to more
cooperate, which imaging technique method will be used to measure his/her lung volume? show less
N/A
PX810401_Standardisation_LungVolumeMeasurement_Imaging_Technique_Other
PX810401420300 If the subject has limited ability to more
cooperate, which imaging technique method will be used to measure his/her lung volume? Other show less
N/A
PX810401_Standardisation_LungVolumeMeasurement_Inline_Filtered
PX810401280000 If in-line filters are being used, does the more
measuring system meet the minimum recommendations for accuracy, precision (reproducibility), flow resistance, and back pressure with the filter installed? show less
N/A
PX810401_Standardisation_LungVolumeMeasurement_MethodOf_Measurement
PX810401370100 Which method from lung volume measurement is more
being used? show less
N/A
PX810401_Standardisation_LungVolumeMeasurement_Method_Frc
PX810401380000 Which method is used for measuring forced more
residual capacity (FRC)? show less
N/A
PX810401_Standardisation_LungVolumeMeasurement_Myocardial_Infarction
PX810401020000 Has the subject suffered from myocardial more
infarction within the last month? show less
N/A
PX810401_Standardisation_LungVolumeMeasurement_Nitrogen_BreathingValve
PX810401400400 If nitrogen washout method is used to more
measure FRC, does the breathing valve for switching the patient from breathing room air to pure oxygen have a dead space of less than 100mL for adults and <2mL/kg in smaller children? show less
N/A
PX810401_Standardisation_LungVolumeMeasurement_Nitrogen_Calibration
PX810401400200 If nitrogen washout method is used to more
measure FRC, were pneumotachographs and other flow-measuring devices calibrated within the last 24 hours by discharging a 3-liter syringe at least 3 times giving a flow range of 0-6L/s? show less
N/A
PX810401_Standardisation_LungVolumeMeasurement_Nitrogen_Calibration_Controls
PX810401400900 If nitrogen washout method is used to more
measure FRC, was the performance of the device tested with biological controls at least once in the past month? show less
N/A
PX810401_Standardisation_LungVolumeMeasurement_Nitrogen_Calibration_Day
PX810401400800 If nitrogen washout method is used to more
measure FRC, before use, was the accuracy of the flow and volume output measured by the device confirmed within the past 24 hours with a calibrating syringe? show less
N/A
PX810401_Standardisation_LungVolumeMeasurement_Nitrogen_Calibration_Zero
PX810401400600 If nitrogen washout method is used to more
measure FRC, was the N2 analyzer tared to zero using 100% O2 and then exposed to room air to confirm calibration? The percentage of N2 for room air should be within 0.5% of the expected reading for room air show less
N/A
PX810401_Standardisation_LungVolumeMeasurement_Nitrogen_Measurement_Technique
PX810401400500 If nitrogen washout method is used to more
measure FRC, does the measurement technique adhere to the following steps? 1) Equipment is turned on and allowed an adequate warm-up time, with calibration as instructed by manufacturer; 2) Patient should be asked if he/she has a perforated eardrum (if so, earplug should be used); 3) Patient is seated comfortable with no need to remove dentures. The procedure is explained, emphasizing the need to avoid leaks around the mouthpiece during the washout and using a nose clip; 4) Patient breathes on the mouthpieces for ~30-60 seconds to become accustomed to the apparatus and to assure a stable end-tidal expiratory level; 5) when breathing is stable and consistent with the end-tidal volume being at FRC, the patient is switched into the circuit so that 100% oxygen is inspired instead of room air; 6) The nitrogen concentration is monitored during the washout. A change in inspired N2 of >1% or sudden large increases in expiratory N2 concentrations indicate a leak; hence the test should be stopped and repeated after a 15-minute period of breathing room air. The washout is considered to be complete when the N2 concentration is less than 1.5% for at least three successive breaths; 8) At least one technically satisfactory measurement should be obtained. If additional washouts are performed, a waiting period of >= 15 minutes is recommended between trials. In patients with severe obstructive or bullous disease, the time between trials should be >= 1 hour. If more than one measurement of FRCN2 is made, the value reported for FRCN2 should be the mean of technically acceptable results that agree within 10%. If only one measurement of FRCN2 is made, caution should be used in the interpretation. show less
N/A
PX810401_Standardisation_LungVolumeMeasurement_Nitrogen_Quality_Control
PX810401400100 If nitrogen washout method is used to more
measure FRC, does the N2 analyzer have an inaccuracy <= 0.2% of full range throughout the entire measuring range (0-80%), have a resolution of <= 0.01%, and have a 95% analyzer response time of <= 60 milliseconds to a 10% step change in nitrogen concentration? show less
N/A
PX810401_Standardisation_LungVolumeMeasurement_Nitrogen_Recalibration
PX810401400700 If nitrogen washout method is used to more
measure FRC, before initial use and once every 6 months thereafter, was the linearity of the N2 analyzer confirmed by measuring the N2 percentage of a calibration gas mixture, where the expected N2 concentration is ~40% and observed values are within 0.5% of the expected concentration? show less
N/A
PX810401_Standardisation_LungVolumeMeasurement_Nitrogen_SamplingRate
PX810401400300 If nitrogen washout method is used to more
measure FRC, for flow and nitrogen signals, does the system have a sampling rate of >= 40 samples/sec? show less
N/A
PX810401_Standardisation_LungVolumeMeasurement_Personnel_Competency
PX810401310000 For personnel directly involved in pulmonary more
function testing, have they established competency in pulmonary function testing? (familiarity with theory and practical aspects of all commonly applied techniques, measurements, calibrations, hygiene, quality control, basic knowledge in lung physiology and pathology) show less
N/A
PX810401_Standardisation_LungVolumeMeasurement_Personnel_CompetencyExam
PX810401330000 Has personnel passed a written and practical more
examination in the presence of an experienced instructor? show less
N/A
PX810401_Standardisation_LungVolumeMeasurement_Personnel_FormalTraining
PX810401300000 For personnel directly involved in pulmonary more
function testing, do they have formal training emphasis in health-related sciences (such as nursing, medical assistant, respiratory therapy, etc)? show less
N/A
PX810401_Standardisation_LungVolumeMeasurement_Personnel_NotebookOf_Records
PX810401350000 Are personnel maintaining a notebook of more
recoreds including but not limited to: calibration procedures, test-performance procedures, calculations, criteria, reference values source, and action to be taken when 'panic' values are observed? show less
N/A
PX810401_Standardisation_LungVolumeMeasurement_Personnel_Notebook_Detail
PX810401360000 Are there detailed statements and/or more
publications on the selection of references values and interpretation of lung function tests along with an assessment of the reliability of the data? show less
N/A
PX810401_Standardisation_LungVolumeMeasurement_Personnel_Qualifications
PX810401290000 Do personnel have the sufficient education more
(2 years college education) and training to understand the fundamentals of the test, know the common signs of pulmonary disease, and be able to manage acquired pulmonary function data? show less
N/A
PX810401_Standardisation_LungVolumeMeasurement_Personnel_RefreshTraining
PX810401340000 If it has been more than 3 years since more
his/her last competency exam or if lung function standards have been recently updated, have personnel taken a spirometry refresher training course? show less
N/A
PX810401_Standardisation_LungVolumeMeasurement_Personnel_TrainingProgram
PX810401320000 Has personnel completed training similar to more
the National Institute for Occupational Safety and Health (NIOSH)-approved spirometry program? show less
N/A
PX810401_Standardisation_LungVolumeMeasurement_SecondMethod_Approach_Ic
PX810401370306 If second method, and using the slow EVC more
approach, what is the mean of technically satisfactory inspiratory capacity (IC) measurements? show less
N/A
PX810401_Standardisation_LungVolumeMeasurement_SecondMethod_Approach_Ivc
PX810401370304 If second method, and using the IVC/ERV more
approach, what is the reported value for the (technically satisfactory) inspiratory vital capacity (IVC)? show less
N/A
PX810401_Standardisation_LungVolumeMeasurement_SecondMethod_Approach_Tlc
PX810401370307 If second method, what is the calculated more
value for total lung capacity (TLC)? (mean of three largest sums of technically acceptable FRC values and linked IC manuevers) show less
N/A
PX810401_Standardisation_LungVolumeMeasurement_SecondMethod_Approach_Vc
PX810401370303 If second method, which approach is used to more
derive the value for vital capacity? show less
N/A
PX810401_Standardisation_LungVolumeMeasurement_SecondMethod_Approach_Vc
PX810401370305 If second method, and using the IVC/ERV more
approach, what is the largest measurement obtained for the vital capacity (VC)? show less
N/A
PX810401_Standardisation_LungVolumeMeasurement_SecondMethod_Erv
PX810401370302 If second method, what is the reported value more
for the (technically satisfactory) expiratory reserve volume (ERV)? show less
N/A
PX810401_Standardisation_LungVolumeMeasurement_SecondMethod_Frc
PX810401370301 If second method, what is the reported value more
for the functional residual capacity (mean of technically satisfactory FRC measurements)? show less
N/A
PX810401_Standardisation_LungVolumeMeasurement_Spirometer_Recalibration
PX810401260000 If the spirometer was disassembled and more
cleaned, was the device re-calibrated? show less
N/A
PX810401_Standardisation_LungVolumeMeasurement_Subjects_Infected_Precautions
PX810401270000 For subjects with transmissible infectious more
diseases, were any of the following precautions taken? Reserving equipment for the sole purpose of testing infected patients, testing such patients at the end of the day to allow time for spirometer disassembly and disinfection, testing patients in their own rooms with adequate ventilation and appropriate protection for the technician show less
N/A
PX810401_Standardisation_LungVolumeMeasurement_Subject_AbilityTo_Cooperate
PX810401200000 Does the subject show signs of limited more
ability to cooperate? show less
N/A
PX810401_Standardisation_LungVolumeMeasurement_Subject_Activities
PX810401040000 Was the subject involved in any of the more
following activities? Smoke within at least 1 hour of testing, consuming alcohol within 4 hours of testing, performing vigorous exercise within 30 minutes of testing, wearing clothing that substantially restricts full chest and abdominal expansion, eating a large meal within 2 hours of testing show less
N/A
PX810401_Standardisation_LungVolumeMeasurement_Subject_Age
PX810401060000 What is the subject's age? Variable Mapping
PX810401_Standardisation_LungVolumeMeasurement_Subject_Arm_Span
PX810401080200 If so, what is the subject's arm span from more
fingertip to fingertip? show less
N/A
PX810401_Standardisation_LungVolumeMeasurement_Subject_Bmi
PX810401110000 What is the subject's body mass index? Variable Mapping
PX810401_Standardisation_LungVolumeMeasurement_Subject_Conditions
PX810401030000 Does the subject suffer from any of the more
following conditions: chest or abdominal pain of any cause, oral or facial pain exacerbated by a mouthpiece, stress incontinence, dementia or confusional state? show less
N/A
PX810401_Standardisation_LungVolumeMeasurement_Subject_Denture
PX810401130000 Does the subject wear any denture or dental more
treatments that are loose and/or that may interfere with performance? show less
N/A
PX810401_Standardisation_LungVolumeMeasurement_Subject_DiseaseOr_Illness
PX810401190000 Does the subject currently suffer from upper more
respiratory or any other contagious disease or illness? show less
N/A
PX810401_Standardisation_LungVolumeMeasurement_Subject_Height
PX810401070000 What is the subject's height? (without more
shoes, feet together) show less
Variable Mapping
PX810401_Standardisation_LungVolumeMeasurement_Subject_Knee_Height
PX810401090200 If so, what is the subject's knee height? N/A
PX810401_Standardisation_LungVolumeMeasurement_Subject_Medications
PX810401120100 Is the subject currently taking any more
medication that may alter lung function? show less
N/A
PX810401_Standardisation_LungVolumeMeasurement_Subject_Medications_LastTime
PX810401120300 If so, when was the last time the drugs were more
administered? show less
N/A
PX810401_Standardisation_LungVolumeMeasurement_Subject_Medications_Type
PX810401120200 If so, what type of medication is the more
subject taking? show less
N/A
PX810401_Standardisation_LungVolumeMeasurement_Subject_OralSores
PX810401210000 Does the subject suffer from open oral sores more
or cuts? show less
N/A
PX810401_Standardisation_LungVolumeMeasurement_Subject_OtherHandicap
PX810401090100 Does the subject suffer from any handicap more
which prevents an accurate measurement from standing height or arm span length? show less
N/A
PX810401_Standardisation_LungVolumeMeasurement_Subject_Position
PX810401050100 Which position will the subject be in for more
the duration of the test? show less
N/A
PX810401_Standardisation_LungVolumeMeasurement_Subject_Position_Other
PX810401050200 Which position will the subject be in for more
the duration of the test? Other show less
N/A
PX810401_Standardisation_LungVolumeMeasurement_Subject_Repeat_EquipmentTester
PX810401170200 If so, is the equipment and operator from more
the previous session the same? show less
N/A
PX810401_Standardisation_LungVolumeMeasurement_Subject_Repeat_OrderConserved
PX810401180000 Is the planned order of lung function tests more
identical to previous tests? show less
N/A
PX810401_Standardisation_LungVolumeMeasurement_Subject_Repeat_TimeRestriction
PX810401170300 If so, is the current test time within 2 more
hours of the previous test time? show less
N/A
PX810401_Standardisation_LungVolumeMeasurement_Subject_Return_Testing
PX810401170100 Is the subject returning for repeat testing? N/A
PX810401_Standardisation_LungVolumeMeasurement_Subject_Thoracic_Deformity
PX810401080100 Does the subject suffer from any deformity more
of the thoracic cage, such as kyphoscoliosis? show less
Variable Mapping
PX810401_Standardisation_LungVolumeMeasurement_Subject_Weight
PX810401100000 What is the subject's weight? Variable Mapping
PX810401_Standardisation_LungVolumeMeasurement_VC
PX810401010000 Which of the following ways is the more
measurement for vital capacity taken? show less
N/A
Sickle Cell Disease
Measure Name:

Lung Function - Lung Volume

Release Date:

July 30, 2015

Definition

Clinical assessment to determine the volume of gas within an individual’s lung.

Purpose

This measure can be used to differentiate obstructive and restrictive pulmonary conditions and to detect and quantify symptoms associated with conditions that impact the lung, such as sickle cell disease, cystic fibrosis, and obstructive airway disease.

Keywords

Lung function, lung volume, lung physiology, diffusion capacity, DLCO, functional residual capacity, FRC, sickle cell disease, SCD, emphysema, cystic fibrosis, CF, asbestosis, lupus, arthritis, smoking, sarcoidosis, carbon monoxide, obstructive airway disease, pulmonary, asthma, sleep apnea, breathing