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Research Domain - Diabetes


	Autoimmune Diseases Related to Type 1 Diabetes National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) Affected Sib-Pair Exam Form
	Diabetic Peripheral Neuropathy Feldman, EL, Stevens, MJ, Thomas, PK, Brown, MB, Canal, N & Greene, DA. (1994). A practical two-step quantitative clinical and electrophysiological assessment for the diagnosis and staging of diabetic neuropathy. Diabetes Care, 17(11), 1281-1289.
	Diabetic Retinopathy Los Angeles Latino Eye Study (LALES) Section D: Ocular Disease History
	Family History of Diabetes Multi-Ethnic Study of Arthrosclerosis (MESA) Exam 2, Family History
	Fasting C-peptide - Assay National Health and Nutrition Examination Survey (NHANES) Laboratory Procedures Manual
	Fasting Plasma Glucose - Blood Draw [link[phenxtoolkit.org/toolkit_content/supplemental_info/diabetes/additional_info/NHANES_OGTT.pdf\|2007-2008 National Health and Nutrition Examination Survey (NHANES) Oral Glucose Tolerance Test Manual]]
	Fasting Plasma Glucose - Glucometer 2005-06 National Health and Nutrition Examination Survey (NHANES) Oral Glucose Tolerance Test (OGTT) Procedures Manual
	Fasting Serum Insulin 2007 National Health and Nutrition Examination Survey (NHANES) Laboratory Procedures Manual
	Glycosylated Hemoglobin - Assay [link[phenxtoolkit.org/toolkit_content/supplemental_info/diabetes/additional_info/NHANES_OGTT.pdf\|2007-2008 National Health and Nutrition Examination Survey (NHANES) Oral Glucose Tolerance Test Manual]]
	Medication Inventory 2000 Multi-Ethnic Study of Arthrosclerosis (MESA), Medications
	Oral Glucose Tolerance Test [link[phenxtoolkit.org/toolkit_content/supplemental_info/diabetes/additional_info/NHANES_OGTT.pdf\|2007-2008 National Health and Nutrition Examination Survey (NHANES) Oral Glucose Tolerance Test Manual]]
	Personal History of Kidney Failure Strong Heart Study, Phase IV-Family Study, Medical History Form
	Personal History of Type 1 and Type 2 Diabetes 2001 Multi-Ethnic Study of Arthrosclerosis (MESA), Exam 1, Medical History
	Serum Creatinine - Assay 2007 National Health and Nutrition Examination Survey (NHANES) Laboratory Procedures Manual
	Urinary Creatinine - Assay 2007 National Health and Nutrition Examination Survey (NHANES) Laboratory Procedures Manual, University of Minnesota Laboratory Procedures Manual for Urinary Creatinine
	Urinary Microalbumin - Assay 2007 National Health and Nutrition Examination Survey (NHANES) Laboratory Procedures Manual, University of Minnesota Laboratory Procedures Manual for Urinary Albumin

Release Date:

May 12, 2010; reviewed October 1, 2015

Scope of Domain:

Scope Elements	Final Measures To Toolkit
Blood Glucose	Fasting Plasma Glucose for Diabetes Screening Glycosylated Hemoglobin Assay that Reflects Long-Term Glucose Concentration Oral Glucose Tolerance Test
Cystatin C
Complications Associated with Diabetes	Diabetic Peripheral Neuropathy Diabetic Retinopathy Personal History of Kidney Failure
Drug Treatments and Pharmaceuticals	Medication Inventory
Family History	Family History of Diabetes
History of Diabetes (Types 1 & 2)	Autoimmune Diseases Related to Type 1 Diabetes Personal History of Type 1 and Type 2 Diabetes
Proinsulin
Urinary Albumin	Urinary Microalbumin Assay for Kidney Function Urinary Creatinine Assay for Kidney Function
Serum Creatinine	Serum Creatinine Assay for Kidney Function
Serum Insulin	Fasting Serum Insulin Fasting C-peptide Assay for Residual Beta Cell Function

Working Group Roster:

WG Members:

Craig Hanis, PhD, Chair University of Texas, Houston Houston, TX	Alain Bertoni, MD, MPH Wake Forest University Winston-Salem, NC
Mercedes Carnethon, PhD Northwestern University Evanston, IL	Catherine Cowie, PhD, MPH National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) Bethesda, MD
Linda Kao, PhD, MHS Johns Hopkins University Baltimore, MD	James Meigs, MD, MPH Harvard University Belmont, MA
Steve Rich, PhD University of Virginia Charlottesville, VA	Charles Rotimi, PhD National Human Genome Research Institute (NHGRI) Bethesda, MD

SC Liaison, WG Manager and WG Supervisor:

William R. Harlan, MD, SC Liaison National Institutes of Health Bethesda, MD	Anne-Lyne McCalla, MPH, RD, WG Manager RTI International Research Triangle Park, NC
Wayne Huggins, PhD, WG Supervisor RTI International Research Triangle Park, NC

Expert Review Panel 1 - Anthropometrics, Diabetes, Nutrition and Dietary Supplements, & Physical Activity and Physical Fitness domains:

ERP Members:

Rick Troiano, PhD, Co-Lead National Cancer Institute (NCI) Risk Factor Monitoring & Methods Branch Rockville, MD	John Hines, PhD, Co-Lead University of Minnesota School of Public Health Minneapolis, MN
Craig Hanis, PhD University of Texas, Houston Houston, TX	Bill Lowe, MD Northwestern University Evanston, IL
Mary Hediger, PhD Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) Rockville, MD	James Pivarnik, PhD Michigan State Univeristy East Lansing, MI
Patrick J. Stover, PhD Cornell University Ithaca, NY	Laura Caulfield, PhD Johns Hopkins Bloomberg School of Public Health Baltimore, MD

SC Liaison, ERP Manager and ERP Supervisor:

Catherine A. McCarty, PhD, SC Liaison Essentia Institute of Rural Health Duluth, MN	Violet Devairakkam, ERP Manager RTI International Rockville, MD
Michael Phillips, MS, ERP Supervisor RTI International Research Triangle Park, NC

Diabetes Supplemental Information includes:

Additional Information for Diabetes Measures:

Protocol Name	Status	DCW	DD	DD Mapping
Autoimmune Diseases Related to Type 1 Diabetes	minor edits	N/A	N/A	N/A
Diabetic Peripheral Neuropathy	minor edits	N/A	N/A	N/A
Diabetic Retinopathy	minor edits	N/A	N/A	N/A
Family History of Diabetes	minor edits	N/A	N/A	N/A
Fasting C-peptide - Assay	minor edits	N/A	N/A	N/A
Fasting Plasma Glucose - Blood Draw	minor edits	N/A	N/A	N/A
Fasting Plasma Glucose - Glucometer	minor edits	N/A	N/A	N/A
Fasting Serum Insulin	minor edits	N/A	N/A	N/A
Glycosylated Hemoglobin - Assay	minor edits	N/A	N/A	N/A
Medication Inventory	minor edits	N/A	N/A	N/A
Oral Glucose Tolerance Test	minor edits	N/A	N/A	N/A
Personal History of Type 1 and Type 2 Diabetes	minor edits	N/A	N/A	N/A
Serum Creatinine - Assay	minor edits	N/A	N/A	N/A
Urinary Creatinine - Assay	minor edits	N/A	N/A	N/A
Urinary Microalbumin - Assay	minor edits	N/A	N/A	N/A
SI_Cystatin_C_Assay_for_Kidney_Function	minor edits	N/A	N/A	N/A
SI_Cystatin_C_Assay_for_Kidney_Function	updated	N/A	N/A	N/A
SI_Fasting_Serum_Proinsulin_Assay_for_Pancreas_Activity	minor edits	N/A	N/A	N/A
SI_Fasting_Serum_Proinsulin_Assay_for_Pancreas_Activity	updated	N/A	N/A	N/A