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Research Domain - Diabetes

Autoimmune Diseases Related to Type 1 Diabetes

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) Affected Sib-Pair Exam Form

Diabetic Peripheral Neuropathy

Feldman, EL, Stevens, MJ, Thomas, PK, Brown, MB, Canal, N & Greene, DA. (1994). A practical two-step quantitative clinical and electrophysiological assessment for the diagnosis and staging of diabetic neuropathy. Diabetes Care, 17(11), 1281-1289.

Diabetic Retinopathy

Los Angeles Latino Eye Study (LALES) Section D: Ocular Disease History

Family History of Diabetes

Multi-Ethnic Study of Arthrosclerosis (MESA) Exam 2, Family History

Fasting C-peptide - Assay

National Health and Nutrition Examination Survey (NHANES) Laboratory Procedures Manual

Fasting Plasma Glucose - Blood Draw

[link[phenxtoolkit.org/toolkit_content/supplemental_info/diabetes/additional_info/NHANES_OGTT.pdf|2007-2008 National Health and Nutrition Examination Survey (NHANES) Oral Glucose Tolerance Test Manual]]

Fasting Plasma Glucose - Glucometer

2005-06 National Health and Nutrition Examination Survey (NHANES) Oral Glucose Tolerance Test (OGTT) Procedures Manual

Fasting Serum Insulin

2007 National Health and Nutrition Examination Survey (NHANES) Laboratory Procedures Manual

Glycosylated Hemoglobin - Assay

[link[phenxtoolkit.org/toolkit_content/supplemental_info/diabetes/additional_info/NHANES_OGTT.pdf|2007-2008 National Health and Nutrition Examination Survey (NHANES) Oral Glucose Tolerance Test Manual]]

Medication Inventory

2000 Multi-Ethnic Study of Arthrosclerosis (MESA), Medications

Oral Glucose Tolerance Test

[link[phenxtoolkit.org/toolkit_content/supplemental_info/diabetes/additional_info/NHANES_OGTT.pdf|2007-2008 National Health and Nutrition Examination Survey (NHANES) Oral Glucose Tolerance Test Manual]]

Personal History of Kidney Failure

Strong Heart Study, Phase IV-Family Study, Medical History Form

Personal History of Type 1 and Type 2 Diabetes

2001 Multi-Ethnic Study of Arthrosclerosis (MESA), Exam 1, Medical History

Serum Creatinine - Assay

2007 National Health and Nutrition Examination Survey (NHANES) Laboratory Procedures Manual

Urinary Creatinine - Assay

2007 National Health and Nutrition Examination Survey (NHANES) Laboratory Procedures Manual, University of Minnesota Laboratory Procedures Manual for Urinary Creatinine

Urinary Microalbumin - Assay

2007 National Health and Nutrition Examination Survey (NHANES) Laboratory Procedures Manual, University of Minnesota Laboratory Procedures Manual for Urinary Albumin

Release Date:

May 12, 2010; reviewed October 1, 2015

Scope of Domain:
Scope Elements Final Measures To Toolkit
Blood Glucose Fasting Plasma Glucose for Diabetes Screening
Glycosylated Hemoglobin Assay that Reflects Long-Term Glucose Concentration
Oral Glucose Tolerance Test
Cystatin C
Complications Associated with Diabetes Diabetic Peripheral Neuropathy
Diabetic Retinopathy
Personal History of Kidney Failure
Drug Treatments and Pharmaceuticals Medication Inventory
Family History Family History of Diabetes
History of Diabetes (Types 1 & 2) Autoimmune Diseases Related to Type 1 Diabetes
Personal History of Type 1 and Type 2 Diabetes
Proinsulin
Urinary Albumin Urinary Microalbumin Assay for Kidney Function
Urinary Creatinine Assay for Kidney Function
Serum Creatinine Serum Creatinine Assay for Kidney Function
Serum Insulin Fasting Serum Insulin
Fasting C-peptide Assay for Residual Beta Cell Function
Working Group Roster:

WG Members:

Craig Hanis, PhD, Chair
University of Texas, Houston
Houston, TX
Alain Bertoni, MD, MPH
Wake Forest University
Winston-Salem, NC
Mercedes Carnethon, PhD
Northwestern University
Evanston, IL
Catherine Cowie, PhD, MPH
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Bethesda, MD
Linda Kao, PhD, MHS
Johns Hopkins University
Baltimore, MD
James Meigs, MD, MPH
Harvard University
Belmont, MA
Steve Rich, PhD
University of Virginia
Charlottesville, VA
Charles Rotimi, PhD
National Human Genome Research Institute (NHGRI)
Bethesda, MD

SC Liaison, WG Manager and WG Supervisor:

William R. Harlan, MD, SC Liaison
National Institutes of Health
Bethesda, MD
Anne-Lyne McCalla, MPH, RD, WG Manager
RTI International
Research Triangle Park, NC
Wayne Huggins, PhD, WG Supervisor
RTI International
Research Triangle Park, NC
Expert Review Panel 1 - Anthropometrics, Diabetes, Nutrition and Dietary Supplements, & Physical Activity and Physical Fitness domains:

ERP Members:

Rick Troiano, PhD, Co-Lead
National Cancer Institute (NCI)
Risk Factor Monitoring & Methods Branch
Rockville, MD
John Hines, PhD, Co-Lead
University of Minnesota School of Public Health
Minneapolis, MN
Craig Hanis, PhD
University of Texas, Houston
Houston, TX
Bill Lowe, MD
Northwestern University
Evanston, IL
Mary Hediger, PhD
Eunice Kennedy Shriver National Institute
of Child Health and Human Development (NICHD)
Rockville, MD
James Pivarnik, PhD
Michigan State Univeristy
East Lansing, MI
Patrick J. Stover, PhD
Cornell University
Ithaca, NY
Laura Caulfield, PhD
Johns Hopkins Bloomberg School of Public Health
Baltimore, MD

SC Liaison, ERP Manager and ERP Supervisor:

Catherine A. McCarty, PhD, SC Liaison
Essentia Institute of Rural Health
Duluth, MN
Violet Devairakkam, ERP Manager
RTI International
Rockville, MD
Michael Phillips, MS, ERP Supervisor
RTI International
Research Triangle Park, NC
Protocol Name Status DCW DD DD Mapping
Autoimmune Diseases Related to Type 1 Diabetes minor edits N/A N/A N/A
Diabetic Peripheral Neuropathy minor edits N/A N/A N/A
Diabetic Retinopathy minor edits N/A N/A N/A
Family History of Diabetes minor edits N/A N/A N/A
Fasting C-peptide - Assay minor edits N/A N/A N/A
Fasting Plasma Glucose - Blood Draw minor edits N/A N/A N/A
Fasting Plasma Glucose - Glucometer minor edits N/A N/A N/A
Fasting Serum Insulin minor edits N/A N/A N/A
Glycosylated Hemoglobin - Assay minor edits N/A N/A N/A
Medication Inventory minor edits N/A N/A N/A
Oral Glucose Tolerance Test minor edits N/A N/A N/A
Personal History of Type 1 and Type 2 Diabetes minor edits N/A N/A N/A
Serum Creatinine - Assay minor edits N/A N/A N/A
Urinary Creatinine - Assay minor edits N/A N/A N/A
Urinary Microalbumin - Assay minor edits N/A N/A N/A
SI_Cystatin_C_Assay_for_Kidney_Function minor edits N/A N/A N/A
SI_Cystatin_C_Assay_for_Kidney_Function updated N/A N/A N/A
SI_Fasting_Serum_Proinsulin_Assay_for_Pancreas_Activity minor edits N/A N/A N/A
SI_Fasting_Serum_Proinsulin_Assay_for_Pancreas_Activity updated N/A N/A N/A