Research Domain - Respiratory
Research Domains:
Alcohol, Tobacco and Other Substances Anthropometrics Cancer Cardiovascular Demographics Diabetes Environmental Exposures Gastrointestinal Geriatrics Infectious Diseases and Immunity Neurology Nutrition and Dietary Supplements Obesity Ocular Oral Health Physical Activity and Physical Fitness Pregnancy Psychiatric Psychosocial Rare Genetic Conditions Reproductive Health Respiratory
Skin, Bone, Muscle and Joint Social Environments Speech and Hearing
Release Date:
January 29, 2010; reviewed November 17, 2017
Scope of Domain:
| Scope Elements | Final Measures To Toolkit |
|---|---|
| Personal History of Conditions and Symptoms | |
| Pneumonia, sarcoidoses | Personal and Family History of Respiratory Symptoms/Diseases (Adult and Child) |
| Chronic obstructive pulmonary disease (COPD) | Personal and Family History of Respiratory Symptoms/Diseases (Adult and Child) |
| Lung cancer | |
| Symptoms, such as wheezing, shortness of breath | Quality of Life as Affected by Respiratory Disease |
| Trauma (acute respiratory disorder) | |
| Allergic reactions to drugs | |
| Anemia | |
| Bronchitis, pleurisy | Personal and Family History of Respiratory Symptoms/Diseases (Adult and Child) |
| Asthma | Personal and Family History of Respiratory Symptoms/Diseases (Adult and Child) |
| Sleep apnea, sleep | Sleep Apnea |
| History of prematurity and early respiratory infections | Personal and Family History of Respiratory Symptoms/Diseases (Adult and Child) |
| Pediatric lung diseases, newborn | |
| Risk factors (past and present) | |
| Exposures | Cotinine |
| Geographic history of patient (histoplasmosis) | |
| Institutional residence (prisoner, nursing home) | |
| Family history (see Personal history of conditions and symptoms) | Personal and Family History of Respiratory Symptoms/Diseases (Adult and Child) |
| Biologic and physiologic assessments | |
| Infectious organisms (pneumococci, staphylococci, gram-negative bacilli | |
| Opportunistic microbes (candida, aspergillus, cytomegalovirus) | |
| Manifestations (dyspnea, cough, hemoptysis [blood in sputum], abnormal production of sputum, cyanosis [bluish discoloration of skin], thoracic pain [pleuritic, pulmonary, chest wall, cardiac], fever) | |
| Blood dyscrasia | |
| Lipoid pneumonia caused by nose drops | |
| Klebsiella pneumonia in chronic alcoholics | |
| Pulmonary function tests (PFT) for: obstructive disease of the airways; restrictive lung disease; alveolar hypoventilation due to malfunctioning of the chest bellows or control mechanisms; and obliterative vascular disease. | Original element broken into three specific measures: Spirometry, Peak Expiratory Flow Rate (PEFR), and Bronchodilator Responsiveness (BDR) |
| Pulmonary embolism | |
| Treatments and procedures (past and present) | |
| Radiologic evaluation (chest X-ray or CXR) | |
| Drug treatments | |
| Chest Computed Tomography (CT) | |
| Cotinine | |
| Immunoglobulin E (Total and Specific) | |
| Pulse Oximetry (rest) | |
| Pulse Oximetry (exercise) | |
| Included as a supplemental measure | |
| Arterial Blood Gas (ABG) | |
| Exercise Capacity/Six-Minute Walk Test | |
| Allergy Skin Prick Test (Supplmental) |
Working Group Roster:
WG Members:
|
Edwin (Ed) K. Silverman, MD, PhD, Chair Brigham and Women's Hospital Harvard Medical School (Channing Laboratory) Boston, MA |
F. Sessions Cole, III, MD Washington University in St. Louis School of Medicine, Department of Pediatrics St. Louis, MO |
|
Jason D. Christie, MD University of Pennsylvania Philadelphia, PA |
Gang Dong, MD, PhD National Institute of Allergy and Infectious Diseases (NIAID) Division of Allergy, Immunology, and Transplantation (DAIT) Bethesda, MD |
|
James (Jim) E. Loyd, MD Vanderbilt University School of Medicine (Division of Pulmonology) Nashville, TN |
Geoffrey McLennan, MB, BS, FRACP, PhD University of Iowa Iowa City, IA |
|
Gail G. Weinmann, MD National Heart, Lung, and Blood Institute (NHLBI) Division of Lung Diseases Bethesda, MD |
SC Liaison, WG Manager and WG Supervisor:
|
Terri H. Beaty, PhD, SC Liaison Johns Hopkins University School of Public Health Baltimore, MD |
Jennifer Lyden, MPH, WG Manager RTI International Statistics and Epidemiology Division Research Triangle Park, NC |
|
Lisa Strader, MPH, WG Supervisor RTI International Research Triangle Park, NC |
Expert Review Panel 6 - Respiratory domain:
ERP Members:
|
David M. Mannino, MD University of Kentucky College of Public Health Lexington, KY |
Stephanie D. Davis, MD Indiana University SChool of Medicine Indianapolis, IN |
SC Liaison, ERP Manager and ERP Supervisor:
|
Daniel R. Masys, MD, FACMI, SC Liaison University of Washington, Seattle School of Medicine Seattle, WA |
Stacie White, BS, ERP Manager RTI International Research Triangle Park, NC |
|
Michael Phillips, MS, ERP Supervisor RTI International Research Triangle Park, NC |
Respiratory Supplemental Information includes:
Additional Information for Respiratory Measures:
| Protocol Name | Status | DCW | DD | DD Mapping |
|---|---|---|---|---|
| Arterial Blood Gas (ABG) | updated | DCW | DD | DD Mapping |
| Biomarker of exposure to nicotine-containing products - Urine | minor edits | N/A | N/A | N/A |
| Chest Computed Tomography (CT) | updated | DCW | DD | N/A |
| Exercise Capacity/Six-Minute Walk Test | updated | DCW | DD | DD Mapping |
| Pulse Oximetry (Rest) | replaced | DCW | DD | DD Mapping |
| Respiratory Rate - Child | minor edits | N/A | N/A | N/A |
| Respiratory Rate - Infant | replaced | DCW | DD | DD Mapping |
| Sleep Apnea - Adult | minor edits | N/A | N/A | N/A |
| Sleep Apnea - Child | minor edits | N/A | N/A | N/A |
| Spirometry - Adult | minor edits | N/A | N/A | N/A |
| SI-Allergy_Skin_Prick_Test | replaced | N/A | N/A | N/A |
| SI-Pulse_Oximetry_Sleep | replaced | N/A | N/A | N/A |