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Research Domain - Respiratory

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Davis, M.D., et al. AARC clinical practice guideline: Blood gas analysis and hemoximetry. Respir Care, 2013
#090202

Schneider, NG, et al. Saliva cotinine levels as a function of collection method. Addiction, 1997
#091702

National Health and Nutrition Examination Survey (NHANES), Cotinine Analysis, 2011-2012
#091703

Man, C. N., et al, Simple, rapid and sensitive assay method for simultaneous quantification of urinary nicotine and cotinine using gas chromatography-mass spectrometry, J CHROMATOGR, 2006
#091701

National Institutes of Health (NIH), COPDGene Study Clinical Center Manual of Procedures, 2009
#090301

 Genetic Epidemiology of COPD Clinical Center Manual of Procedures, 2014
#090402

Six-Minute Walk Test (6MWT)
#090602

Williams, P. B., et al, Analytic precision and accuracy of commercial immunoassays for specific IgE: Establishing a standard, J ALLERGY CLIN IMMUN, 2000
#090701

Miller, M. R., et al, Standardization of spirometry. Series “ATS/ERS task force: Standardization of lung function testing.”, EUR RESPIR J, 2005
#090801

American Thoracic Society-Division of Lung Diseases Questionnaire (ATS-DLD 78) & Genetic Epidemiology of COPD Study (COPDGene)
#090901

International Study of Asthma and Allergies in Childhood (ISAAC) Manual
#090902

AARC Clinical Practice Guideline: Exercise Testing for Evaluation of Hypoxemia and/or Desaturation: revision & update. Resp Care, 2001
#091001

World Health Organization (WHO), Pulse oximetry training manual, 2011
#091102

St. George’s Respiratory Questionnaire (SGRQ)
#091301

Potter, P. A., et al. Fundamentals of Nursing, 1985
#091403

Wallis, L. A., Healy, et al, Age related reference ranges for respiration rate and heart rate from 4 to 16 years, ARCH DIS CHILD, 2005
#091402

Fleming, S, et al. Normal ranges of heart rate and respiratory rate in children from birth to 18 years of age: A systemic review of observational studies. Lancer, 2011
#091404

Berlin Questionnaire
#091501

The Pediatric Sleep Questionnaire (PSQ), Version 070424
#091502

Miller, M. R., et al, Standardization of spirometry. Series “ATS/ERS task force: Standardization of lung function testing.”, EUR RESPIR J, 2005
#091601

Beydon, N., et al, An official American Thoracic Society/European Respiratory Society statement: Pulmonary function testing in preschool children, AM J RESP CRIT CARE, 2007
#091602
Release Date:

January 29, 2010; reviewed November 17, 2017

Scope of Domain:
Scope Elements Final Protocols To Toolkit (39)
Personal History of Conditions and Symptoms
Pneumonia, sarcoidoses Personal and Family History of Respiratory Symptoms/Diseases (Adult and Child)
Chronic obstructive pulmonary disease (COPD) Personal and Family History of Respiratory Symptoms/Diseases (Adult and Child)
Lung cancer
Symptoms, such as wheezing, shortness of breath Quality of Life as Affected by Respiratory Disease
Trauma (acute respiratory disorder)
Allergic reactions to drugs
Anemia
Bronchitis, pleurisy Personal and Family History of Respiratory Symptoms/Diseases (Adult and Child)
Asthma Personal and Family History of Respiratory Symptoms/Diseases (Adult and Child)
Sleep apnea, sleep Sleep Apnea
History of prematurity and early respiratory infections Personal and Family History of Respiratory Symptoms/Diseases (Adult and Child)
Pediatric lung diseases, newborn
Risk factors (past and present)
Exposures Cotinine
Geographic history of patient (histoplasmosis)
Institutional residence (prisoner, nursing home)
Family history (see Personal history of conditions and symptoms) Personal and Family History of Respiratory Symptoms/Diseases (Adult and Child)
Biologic and physiologic assessments
Infectious organisms (pneumococci, staphylococci, gram-negative bacilli
Opportunistic microbes (candida, aspergillus, cytomegalovirus)
Manifestations (dyspnea, cough, hemoptysis [blood in sputum], abnormal production of sputum, cyanosis [bluish discoloration of skin], thoracic pain [pleuritic, pulmonary, chest wall, cardiac], fever)
Blood dyscrasia
Lipoid pneumonia caused by nose drops
Klebsiella pneumonia in chronic alcoholics
Pulmonary function tests (PFT) for: obstructive disease of the airways; restrictive lung disease; alveolar hypoventilation due to malfunctioning of the chest bellows or control mechanisms; and obliterative vascular disease. Original element broken into three specific measures: Spirometry, Peak Expiratory Flow Rate (PEFR), and Bronchodilator Responsiveness (BDR)
Pulmonary embolism
Treatments and procedures (past and present)
Radiologic evaluation (chest X-ray or CXR)
Drug treatments
Chest Computed Tomography (CT)
Cotinine
Immunoglobulin E (Total and Specific)
Pulse Oximetry (rest)
Pulse Oximetry (exercise)
Included as a supplemental measure
Arterial Blood Gas (ABG)
Exercise Capacity/Six-Minute Walk Test
Allergy Skin Prick Test (Supplmental)
Working Group Roster:

WG Members:

Edwin (Ed) K. Silverman, MD, PhD, Chair
Brigham and Women's Hospital
Harvard Medical School (Channing Laboratory)
Boston, MA
F. Sessions Cole, III, MD
Washington University in St. Louis
School of Medicine, Department of Pediatrics
St. Louis, MO
Jason D. Christie, MD
University of Pennsylvania
Philadelphia, PA
Gang Dong, MD, PhD
National Institute of Allergy and Infectious Diseases (NIAID)
Division of Allergy, Immunology, and Transplantation (DAIT)
Bethesda, MD
James (Jim) E. Loyd, MD
Vanderbilt University
School of Medicine (Division of Pulmonology)
Nashville, TN
Geoffrey McLennan, MB, BS, FRACP, PhD
University of Iowa
Iowa City, IA
Gail G. Weinmann, MD
National Heart, Lung, and Blood Institute (NHLBI)
Division of Lung Diseases
Bethesda, MD

SC Liaison, WG Manager and WG Supervisor:

Terri H. Beaty, PhD, SC Liaison
Johns Hopkins University
School of Public Health
Baltimore, MD
Jennifer Lyden, MPH, WG Manager
RTI International
Statistics and Epidemiology Division
Research Triangle Park, NC
Lisa Strader, MPH, WG Supervisor
RTI International
Research Triangle Park, NC
Expert Review Panel 6 - Respiratory domain:

ERP Members:

David M. Mannino, MD
University of Kentucky College of Public Health
Lexington, KY
Stephanie D. Davis, MD
Indiana University School of Medicine
Indianapolis, IN

SC Liaison, ERP Manager and ERP Supervisor:

Daniel R. Masys, MD, FACMI, SC Liaison
University of Washington
School of Medicine
Seattle, WA
Stacie White, BS, ERP Manager
RTI International
Research Triangle Park, NC
Michael Phillips, MS, ERP Supervisor
RTI International
Research Triangle Park, NC
Respiratory Supplemental Information includes:
Additional Information for Respiratory Measures: