Protocol - Sex Assigned at Birth
Participants (or proxy) indicate the biological sex assigned at birth. It can be self-administered or interviewer administered.
What was your biological sex assigned at birth?
[ ] Female
[ ] Male
[ ] Intersex
[ ] None of these describe me (optional free text)
[ ] Prefer not to answer
Personnel and Training Required
The PhenX Steering Committee acknowledges these questions can be administered in a computerized or noncomputerized format (i.e., paper-and-pencil instrument). Computer software is necessary to develop computer-assisted instruments. The interviewer will require a laptop computer/handheld computer to administer a computer-assisted questionnaire.
|Specialized requirements for biospecimen collection||No|
|Average time of greater than 15 minutes in an unaffected individual||No|
Mode of Administration
Self-administered or interviewer-administered questionnaire
Adults 18 years and older
This protocol was selected because it is both the most up-to-date and in use by the national All of Us research program.
English, Other languages available at source
Process and Review
The NIH Sexual and Gender Minority Research Office (SGMRO) reviewed this protocol in August 2023.
- Changed Biological Sex Assigned at Birth protocol name to Sex Assigned at Birth
- Made Gender Identity and Sex Assigned at Birth protocols “essential” to one another
- Added NASEM report reference
- Removed The Precision Medicine Initiative Cohort Program, Collins, F.S. and Varmus, H., and National Research Council references
- Updated Specific Instructions
- Updated Protocol Definition
- Updated Purpose
- Updated Keywords
Protocol Name from Source
All of Us Research Program, Participant Provided Information (PPI), 2018
All of Us Research Program Participant Provided Information (PPI) Version: December 17, 2018
National Academies of Sciences, Engineering, and Medicine; Division of Behavioral and Social Sciences and Education; Committee on National Statistics; Committee on Measuring Sex, Gender Identity, and Sexual Orientation. Measuring Sex, Gender Identity, and Sexual Orientation. Becker T, Chin M, Bates N, editors. Washington (DC): National Academies Press (US); 2022 Mar 9. PMID: 35286054.
The GenIUSS Group. (2014). Best Practices for Asking Questions to Identify Transgender and Other Gender Minority Respondents on Population-Based Surveys. J.L. Herman (Ed.). Los Angeles, CA: The Williams Institute.
|Variable Name||Variable ID||Variable Description||dbGaP Mapping|
|PX011601010100||What was your biological sex assigned at birth?||N/A|
|PX011601010200||What was your biological sex assigned at more||N/A|
Biological sex assigned at birth
June 4, 2019
The indication of the sex assigned to an individual at the time of birth, typically assigned based on visual inspection of infant anatomy. If sex assigned at birth and gender identity are different, it may indicate that a person is transgender.
Sex assigned at birth is intended to record sex at birth, often based on visual inspection of an infant. Sex assigned at birth is intended to be used in conjunction with the Gender Identity protocol.
biological sex assigned at birth, female, male, Intersex, gender, Demographics-Populations with HD
|Protocol ID||Protocol Name|
|11601||Sex Assigned at Birth|
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