Protocol - Biological Sex Assigned at Birth
Participants (or proxy) indicate the biological sex assigned at birth. It can be self-administered or interviewer administered.
This protocol can be used in conjunction with the Gender Identity protocol. This use of the protocol may be preferred to allow a research participant to differentiate their biological sex assigned at birth with how they currently define their gender.
What was your biological sex assigned at birth?
[ ] Female
[ ] Male
[ ] Intersex
[ ] None of these describe me (optional free text)
[ ] Prefer not to answer
Personnel and Training Required
The PhenX Steering Committee acknowledges these questions can be administered in a computerized or noncomputerized format (i.e., paper-and-pencil instrument). Computer software is necessary to develop computer-assisted instruments. The interviewer will require a laptop computer/handheld computer to administer a computer-assisted questionnaire.
|Specialized requirements for biospecimen collection||No|
|Average time of greater than 15 minutes in an unaffected individual||No|
Mode of Administration
Self-administered or interviewer-administered questionnaire
Adults 18 years and older
This protocol was selected because it is both the most up-to-date and in use by the national All of Us research program.
English, Other languages available at source
|caDSR Common Data Elements (CDE)||Person Gender Text Type||2200604||CDE Browser|
Process and Review
Protocol Name from Source
All of Us Research Program, Participant Provided Information (PPI), 2018
All of Us Research Program Participant Provided Information (PPI) Version: December 17, 2018
The Precision Medicine Initiative Cohort Program – Building a Research Foundation for 21st Century Medicine Precision Medicine Initiative (PMI) Working Group Report to the Advisory Committee to the Director, NIH September 17, 2015
Collins, F. S. and Varmus, H. (2015). A New Initiative on Precision Medicine. N Engl J Med, 372, 793-795
National Research Council. Toward precision medicine: building a knowledge network for biomedical research and a new taxonomy of disease. Washington, DC: National Academies Press, 2011 (http://www.nap.edu/catalog/13284/toward-precision-medicine-building-a-knowledge-network-for-biomedical-research).
The GenIUSS Group. (2014). Best Practices for Asking Questions to Identify Transgender and Other Gender Minority Respondents on Population-Based Surveys. J.L. Herman (Ed.). Los Angeles, CA: The Williams Institute.
|Variable Name||Variable ID||Variable Description||dbGaP Mapping|
|PX011601010100||What was your biological sex assigned at birth?||N/A|
|PX011601010200||What was your biological sex assigned at more||N/A|
Biological sex assigned at birth
June 4, 2019
The indication of the biological sex assigned to an individual at the time of birth. This usually aligns with a person’s anatomical sex, chromosomal sex, and phenotype.
Biological sex is an important piece of demographic information impacting many health outcomes.
biological sex assigned at birth, female, male, Intersex, gender, Demographics-Populations with HD
|Protocol ID||Protocol Name|
|11601||Biological Sex Assigned at Birth|
- Joint Effects of PON1 Polymorphisms and Vegetable Intake on Ischemic Stroke: A Family-Based Case Control Study
- Perceived Discrimination as a Risk Factor for Use of Emerging Tobacco Products: More Similarities Than Differences Across Demographic Groups and Attributions for Discrimination